Baseline characteristics of the Health ABC study cohort stratified according to the 2 mg/L high-sensitivity C-reactive protein cut-off
| . | . | Health ABC (n = 2803) . | . | . |
|---|---|---|---|---|
| hsCRP range [mg/L] | Overall [0.15, 85.18] | [0.15, 2] (n = 1598) | [2, 85.18] (n = 1205) | P |
| Age, years | 72.6 (2.9) | 72.7 (2.9) | 72.4 (2.8) | 0.003 |
| Male sex, n (%) | 1327 (47.3) | 849 (53.1) | 478 (39.7) | <0.001 |
| Diabetes, n (%) | 410 (14.6) | 191 (12.0) | 219 (18.2) | <0.001 |
| Obesitya, n (%) | 504 (18.8) | 194 (12.6) | 310 (27.0) | <0.001 |
| Current or ex-smoker, n (%) | 1691 (60.3) | 941 (58.9) | 750 (62.2) | 0.079 |
| Regular drinker, n (%) | 1392 (49.7) | 822 (51.4) | 570 (47.3) | 0.033 |
| MI, n (%) | 294 (10.6) | 166 (10.5) | 128 (10.7) | 0.874 |
| Angina, n (%) | 294 (10.7) | 159 (10.1) | 135 (11.5) | 0.260 |
| Stroke, n (%) | 59 (2.1) | 27 (1.7) | 32 (2.7) | 0.101 |
| CKDb, n (%) | 745 (26.6) | 384 (24.0) | 361 (30.0) | <0.001 |
| COPD, n (%) | 114 (4.1) | 52 (3.3) | 62 (5.1) | 0.016 |
| . | . | Health ABC (n = 2803) . | . | . |
|---|---|---|---|---|
| hsCRP range [mg/L] | Overall [0.15, 85.18] | [0.15, 2] (n = 1598) | [2, 85.18] (n = 1205) | P |
| Age, years | 72.6 (2.9) | 72.7 (2.9) | 72.4 (2.8) | 0.003 |
| Male sex, n (%) | 1327 (47.3) | 849 (53.1) | 478 (39.7) | <0.001 |
| Diabetes, n (%) | 410 (14.6) | 191 (12.0) | 219 (18.2) | <0.001 |
| Obesitya, n (%) | 504 (18.8) | 194 (12.6) | 310 (27.0) | <0.001 |
| Current or ex-smoker, n (%) | 1691 (60.3) | 941 (58.9) | 750 (62.2) | 0.079 |
| Regular drinker, n (%) | 1392 (49.7) | 822 (51.4) | 570 (47.3) | 0.033 |
| MI, n (%) | 294 (10.6) | 166 (10.5) | 128 (10.7) | 0.874 |
| Angina, n (%) | 294 (10.7) | 159 (10.1) | 135 (11.5) | 0.260 |
| Stroke, n (%) | 59 (2.1) | 27 (1.7) | 32 (2.7) | 0.101 |
| CKDb, n (%) | 745 (26.6) | 384 (24.0) | 361 (30.0) | <0.001 |
| COPD, n (%) | 114 (4.1) | 52 (3.3) | 62 (5.1) | 0.016 |
Bold indicates statistically significant. BMI, body mass index; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; hsCRP, high-sensitivity C-reactive protein; MI, myocardial infarction.
aBody mass index ≥ 30 kg/m2.
beGFR < 60 mL/min/1.73 m2, as calculated with the CKD-EPI formula.
Baseline characteristics of the Health ABC study cohort stratified according to the 2 mg/L high-sensitivity C-reactive protein cut-off
| . | . | Health ABC (n = 2803) . | . | . |
|---|---|---|---|---|
| hsCRP range [mg/L] | Overall [0.15, 85.18] | [0.15, 2] (n = 1598) | [2, 85.18] (n = 1205) | P |
| Age, years | 72.6 (2.9) | 72.7 (2.9) | 72.4 (2.8) | 0.003 |
| Male sex, n (%) | 1327 (47.3) | 849 (53.1) | 478 (39.7) | <0.001 |
| Diabetes, n (%) | 410 (14.6) | 191 (12.0) | 219 (18.2) | <0.001 |
| Obesitya, n (%) | 504 (18.8) | 194 (12.6) | 310 (27.0) | <0.001 |
| Current or ex-smoker, n (%) | 1691 (60.3) | 941 (58.9) | 750 (62.2) | 0.079 |
| Regular drinker, n (%) | 1392 (49.7) | 822 (51.4) | 570 (47.3) | 0.033 |
| MI, n (%) | 294 (10.6) | 166 (10.5) | 128 (10.7) | 0.874 |
| Angina, n (%) | 294 (10.7) | 159 (10.1) | 135 (11.5) | 0.260 |
| Stroke, n (%) | 59 (2.1) | 27 (1.7) | 32 (2.7) | 0.101 |
| CKDb, n (%) | 745 (26.6) | 384 (24.0) | 361 (30.0) | <0.001 |
| COPD, n (%) | 114 (4.1) | 52 (3.3) | 62 (5.1) | 0.016 |
| . | . | Health ABC (n = 2803) . | . | . |
|---|---|---|---|---|
| hsCRP range [mg/L] | Overall [0.15, 85.18] | [0.15, 2] (n = 1598) | [2, 85.18] (n = 1205) | P |
| Age, years | 72.6 (2.9) | 72.7 (2.9) | 72.4 (2.8) | 0.003 |
| Male sex, n (%) | 1327 (47.3) | 849 (53.1) | 478 (39.7) | <0.001 |
| Diabetes, n (%) | 410 (14.6) | 191 (12.0) | 219 (18.2) | <0.001 |
| Obesitya, n (%) | 504 (18.8) | 194 (12.6) | 310 (27.0) | <0.001 |
| Current or ex-smoker, n (%) | 1691 (60.3) | 941 (58.9) | 750 (62.2) | 0.079 |
| Regular drinker, n (%) | 1392 (49.7) | 822 (51.4) | 570 (47.3) | 0.033 |
| MI, n (%) | 294 (10.6) | 166 (10.5) | 128 (10.7) | 0.874 |
| Angina, n (%) | 294 (10.7) | 159 (10.1) | 135 (11.5) | 0.260 |
| Stroke, n (%) | 59 (2.1) | 27 (1.7) | 32 (2.7) | 0.101 |
| CKDb, n (%) | 745 (26.6) | 384 (24.0) | 361 (30.0) | <0.001 |
| COPD, n (%) | 114 (4.1) | 52 (3.3) | 62 (5.1) | 0.016 |
Bold indicates statistically significant. BMI, body mass index; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; hsCRP, high-sensitivity C-reactive protein; MI, myocardial infarction.
aBody mass index ≥ 30 kg/m2.
beGFR < 60 mL/min/1.73 m2, as calculated with the CKD-EPI formula.
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