Table 2.

Uni- and multivariable analysis for progression-free survival (PFS).

CovariateUnivariable analysisMultivariable analysis
HR (95%CI)P-valuenHR (95%CI)P-value
Age10.98 (0.96-1.00).0161150.98 (0.96-1.00).098
Male sex0.62 (0.39-0.99).0441150.65 (0.37-1.15).14
CCI0.84 (0.63-1.10).201150.87 (0.66-1.16).34
ECOG150
 0-1Reference35
 2-31.98 (1.05-3.74).03515
Location of primary tumour.31115
 GEJ (Siewart I-III)Reference55Reference
 Esophagus0.81 (0.41-1.6).54110.83 (0.41-1.67).60
 Gastric1.30 (0.84-2.03).24491.16 (0.69-1.97).59
Tumour grade.034115
 G1Reference8
 G21.73 (0.62-4.28).3228
 G32.91 (1.14-7.47).0349
HER2 status0.78 (0.49-1.23).291150.69 (0.43-1.11).13
CovariateUnivariable analysisMultivariable analysis
HR (95%CI)P-valuenHR (95%CI)P-value
Age10.98 (0.96-1.00).0161150.98 (0.96-1.00).098
Male sex0.62 (0.39-0.99).0441150.65 (0.37-1.15).14
CCI0.84 (0.63-1.10).201150.87 (0.66-1.16).34
ECOG150
 0-1Reference35
 2-31.98 (1.05-3.74).03515
Location of primary tumour.31115
 GEJ (Siewart I-III)Reference55Reference
 Esophagus0.81 (0.41-1.6).54110.83 (0.41-1.67).60
 Gastric1.30 (0.84-2.03).24491.16 (0.69-1.97).59
Tumour grade.034115
 G1Reference8
 G21.73 (0.62-4.28).3228
 G32.91 (1.14-7.47).0349
HER2 status0.78 (0.49-1.23).291150.69 (0.43-1.11).13

PFS is defined as start of ram/pac to time of disease progression or last dose of ram/pac.

1At the time of starting rampac.

Table 2.

Uni- and multivariable analysis for progression-free survival (PFS).

CovariateUnivariable analysisMultivariable analysis
HR (95%CI)P-valuenHR (95%CI)P-value
Age10.98 (0.96-1.00).0161150.98 (0.96-1.00).098
Male sex0.62 (0.39-0.99).0441150.65 (0.37-1.15).14
CCI0.84 (0.63-1.10).201150.87 (0.66-1.16).34
ECOG150
 0-1Reference35
 2-31.98 (1.05-3.74).03515
Location of primary tumour.31115
 GEJ (Siewart I-III)Reference55Reference
 Esophagus0.81 (0.41-1.6).54110.83 (0.41-1.67).60
 Gastric1.30 (0.84-2.03).24491.16 (0.69-1.97).59
Tumour grade.034115
 G1Reference8
 G21.73 (0.62-4.28).3228
 G32.91 (1.14-7.47).0349
HER2 status0.78 (0.49-1.23).291150.69 (0.43-1.11).13
CovariateUnivariable analysisMultivariable analysis
HR (95%CI)P-valuenHR (95%CI)P-value
Age10.98 (0.96-1.00).0161150.98 (0.96-1.00).098
Male sex0.62 (0.39-0.99).0441150.65 (0.37-1.15).14
CCI0.84 (0.63-1.10).201150.87 (0.66-1.16).34
ECOG150
 0-1Reference35
 2-31.98 (1.05-3.74).03515
Location of primary tumour.31115
 GEJ (Siewart I-III)Reference55Reference
 Esophagus0.81 (0.41-1.6).54110.83 (0.41-1.67).60
 Gastric1.30 (0.84-2.03).24491.16 (0.69-1.97).59
Tumour grade.034115
 G1Reference8
 G21.73 (0.62-4.28).3228
 G32.91 (1.14-7.47).0349
HER2 status0.78 (0.49-1.23).291150.69 (0.43-1.11).13

PFS is defined as start of ram/pac to time of disease progression or last dose of ram/pac.

1At the time of starting rampac.

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