Table 4: Open in new tab Logistic...

Death

LCI

UCI

Hypernatremia

2.136

1.119

4.077

0.021*

Male sex

0.840

0.440

1.604

0.598

Weight

0.997

0.983

1.012

0.750

Height

14.78

0.466

468.1

0.127

Systolic pressure

1.006

0.993

1.019

0.305

Temperature

1.834

1.191

2.823

0.006*

Heart rate

1.015

1.000

1.029

0.038*

Fluid adjustment

4.289

1.452

12.67

0.008*

Antibiotic adjustment

1.852

0.825

4.154

0.135

Nutrition adjustment

5.548

0.264

116.2

0.270

Change to no hyperchloremic fluid

0.168

0.017

1.593

0.120

Urea

1.002

0.999

1.005

0.097

KRT

LCI

UCI

Hypernatremia

1.231

0.616

2.460

0.555

Male sex

0.892

0.393

1.748

0.623

Weight

0.995

0.978

1.012

0.597

Height

1.414

0.025

78.37

0.866

Systolic pressure

1.012

0.998

1.027

0.086

Temperature

1.542

0.984

2.418

0.059

Heart rate

1.027

1.011

1.044

0.001*

Fluid adjustment

3.991

1.213

13.13

0.023*

Antibiotic adjustment

3.470

1.532

7.857

0.003*

Nutrition adjustment

1.652

0.178

15.32

0.658

Change to no hyperchloremic fluid

0.822

0.120

5.631

0.842

Urea

1.005

1.002

1.009

0.001*

Decrease in eGFR

LCI

UCI

Hypernatremia

20.14

7.695

52.72

<0.001*

Male sex

0.005

0.001

0.018

<0.001*

Weight

0.979

0.954

1.006

0.130

Height

0.324

0.001

101.4

0.701

Systolic pressure

0.997

0.978

1.017

0.807

Temperature

0.888

0.465

1.696

0.720

Heart rate

1.008

0.987

1.030

0.424

Fluid adjustment

0.777

0.156

3.864

0.758

Antibiotic adjustment

0.378

0.093

1.539

0.175

Nutrition adjustment

2.150

0.112

41.01

0.611

Change to no hyperchloremic fluid

0.665

0.066

6.690

0.730

Urea

1.002

0.997

1.007

0.282

Table 4:

Open in new tab

Logistic regression model for each of the components of MAKE10 by the presence of hypernatremia.

Death	OR	LCI	UCI	P
Hypernatremia	2.136	1.119	4.077	0.021*
Male sex	0.840	0.440	1.604	0.598
Weight	0.997	0.983	1.012	0.750
Height	14.78	0.466	468.1	0.127
Systolic pressure	1.006	0.993	1.019	0.305
Temperature	1.834	1.191	2.823	0.006*
Heart rate	1.015	1.000	1.029	0.038*
Fluid adjustment	4.289	1.452	12.67	0.008*
Antibiotic adjustment	1.852	0.825	4.154	0.135
Nutrition adjustment	5.548	0.264	116.2	0.270
Change to no hyperchloremic fluid	0.168	0.017	1.593	0.120
Urea	1.002	0.999	1.005	0.097
KRT	OR	LCI	UCI	P

Hypernatremia	1.231	0.616	2.460	0.555
Male sex	0.892	0.393	1.748	0.623
Weight	0.995	0.978	1.012	0.597
Height	1.414	0.025	78.37	0.866
Systolic pressure	1.012	0.998	1.027	0.086
Temperature	1.542	0.984	2.418	0.059
Heart rate	1.027	1.011	1.044	0.001*
Fluid adjustment	3.991	1.213	13.13	0.023*
Antibiotic adjustment	3.470	1.532	7.857	0.003*
Nutrition adjustment	1.652	0.178	15.32	0.658
Change to no hyperchloremic fluid	0.822	0.120	5.631	0.842
Urea	1.005	1.002	1.009	0.001*
Decrease in eGFR	OR	LCI	UCI	P

Hypernatremia	20.14	7.695	52.72	<0.001*
Male sex	0.005	0.001	0.018	<0.001*
Weight	0.979	0.954	1.006	0.130
Height	0.324	0.001	101.4	0.701
Systolic pressure	0.997	0.978	1.017	0.807
Temperature	0.888	0.465	1.696	0.720
Heart rate	1.008	0.987	1.030	0.424
Fluid adjustment	0.777	0.156	3.864	0.758
Antibiotic adjustment	0.378	0.093	1.539	0.175
Nutrition adjustment	2.150	0.112	41.01	0.611
Change to no hyperchloremic fluid	0.665	0.066	6.690	0.730
Urea	1.002	0.997	1.007	0.282

Death	OR	LCI	UCI	P
Hypernatremia	2.136	1.119	4.077	0.021*
Male sex	0.840	0.440	1.604	0.598
Weight	0.997	0.983	1.012	0.750
Height	14.78	0.466	468.1	0.127
Systolic pressure	1.006	0.993	1.019	0.305
Temperature	1.834	1.191	2.823	0.006*
Heart rate	1.015	1.000	1.029	0.038*
Fluid adjustment	4.289	1.452	12.67	0.008*
Antibiotic adjustment	1.852	0.825	4.154	0.135
Nutrition adjustment	5.548	0.264	116.2	0.270
Change to no hyperchloremic fluid	0.168	0.017	1.593	0.120
Urea	1.002	0.999	1.005	0.097
KRT	OR	LCI	UCI	P

Hypernatremia	1.231	0.616	2.460	0.555
Male sex	0.892	0.393	1.748	0.623
Weight	0.995	0.978	1.012	0.597
Height	1.414	0.025	78.37	0.866
Systolic pressure	1.012	0.998	1.027	0.086
Temperature	1.542	0.984	2.418	0.059
Heart rate	1.027	1.011	1.044	0.001*
Fluid adjustment	3.991	1.213	13.13	0.023*
Antibiotic adjustment	3.470	1.532	7.857	0.003*
Nutrition adjustment	1.652	0.178	15.32	0.658
Change to no hyperchloremic fluid	0.822	0.120	5.631	0.842
Urea	1.005	1.002	1.009	0.001*
Decrease in eGFR	OR	LCI	UCI	P

Hypernatremia	20.14	7.695	52.72	<0.001*
Male sex	0.005	0.001	0.018	<0.001*
Weight	0.979	0.954	1.006	0.130
Height	0.324	0.001	101.4	0.701
Systolic pressure	0.997	0.978	1.017	0.807
Temperature	0.888	0.465	1.696	0.720
Heart rate	1.008	0.987	1.030	0.424
Fluid adjustment	0.777	0.156	3.864	0.758
Antibiotic adjustment	0.378	0.093	1.539	0.175
Nutrition adjustment	2.150	0.112	41.01	0.611
Change to no hyperchloremic fluid	0.665	0.066	6.690	0.730
Urea	1.002	0.997	1.007	0.282

Abbreviations: MAKE: major adverse kidney events. OR: Odds ratio. LCI: lower confidence interval. UCI: upper confidence interval.

This Feature Is Available To Subscribers Only