Table 2.
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Previous reports of tumors with the somatic MEN1 p.Leu89Arg variant

Primary organHistologyZygosityReference
PancreasCarcinoid-endocrine tumor (glucagonoma)Homozygous[11]
ParathyroidHyperplasiaUnknown[12]
LungCarcinoid-endocrine tumor (atypical)Unknown[13]
BreastCarcinoma (lobular carcinoma)Heterozygous[14]
BreastCarcinoma (lobular carcinoma)Unknown[15]
Primary organHistologyZygosityReference
PancreasCarcinoid-endocrine tumor (glucagonoma)Homozygous[11]
ParathyroidHyperplasiaUnknown[12]
LungCarcinoid-endocrine tumor (atypical)Unknown[13]
BreastCarcinoma (lobular carcinoma)Heterozygous[14]
BreastCarcinoma (lobular carcinoma)Unknown[15]
Table 2.
Open in new tab

Previous reports of tumors with the somatic MEN1 p.Leu89Arg variant

Primary organHistologyZygosityReference
PancreasCarcinoid-endocrine tumor (glucagonoma)Homozygous[11]
ParathyroidHyperplasiaUnknown[12]
LungCarcinoid-endocrine tumor (atypical)Unknown[13]
BreastCarcinoma (lobular carcinoma)Heterozygous[14]
BreastCarcinoma (lobular carcinoma)Unknown[15]
Primary organHistologyZygosityReference
PancreasCarcinoid-endocrine tumor (glucagonoma)Homozygous[11]
ParathyroidHyperplasiaUnknown[12]
LungCarcinoid-endocrine tumor (atypical)Unknown[13]
BreastCarcinoma (lobular carcinoma)Heterozygous[14]
BreastCarcinoma (lobular carcinoma)Unknown[15]
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