Table 3. Open in new tab Comparison of...

Table 3.

Comparison of DeepES with existing tools.

Characteristics	DeepES	DeepEC	CLEAN	EnzBERT	E-zyme 2	BLAST
Input	Protein sequences, reactions	Protein sequence	Protein sequence	Protein sequence	Substrate, product	Protein sequence
Output	Candidate genes	EC number	EC number	EC number	RClass	Sequence identity
Run independently of databases	○	○	○	○	×	×
Explore any sequence space	○	○	○	○	×	○
Can handle orphan enzymes	○	○	○	○	×	×
Can handle incorporate reactions	○	△	△	△	○	×
Compounds derived from amino acids	○	×	×	×	○	×
Leverage genome-context information	○	×	×	×	×	×

Characteristics	DeepES	DeepEC	CLEAN	EnzBERT	E-zyme 2	BLAST
Input	Protein sequences, reactions	Protein sequence	Protein sequence	Protein sequence	Substrate, product	Protein sequence
Output	Candidate genes	EC number	EC number	EC number	RClass	Sequence identity
Run independently of databases	○	○	○	○	×	×
Explore any sequence space	○	○	○	○	×	○
Can handle orphan enzymes	○	○	○	○	×	×
Can handle incorporate reactions	○	△	△	△	○	×
Compounds derived from amino acids	○	×	×	×	○	×
Leverage genome-context information	○	×	×	×	×	×