Table 1.

Patient Cohort Characteristics

Patient Characteristics
Age at diagnosis mean ± SD, N 64.4 ± 11.8, 230
Female sex—n (%)88 (36%)
BMI mean ± SD, N 26.0 ± 5.1, 179
Tumor MGMT promoter methylation—n (%), N90 (42%), 217
KPS score at presentation—n (%), N
≥70%150 (65%), 230
<70%80 (35%)
Surgery type—n (%), N
 Biopsy only57 (25%), 230
 Partial resection98 (43%)
 Complete resection75 (33%)
Adjuvant therapy received—N (%), N
 Adjuvant chemotherapy only15 (7%), 228
 Adjuvant radiotherapy only15 (7%)
 Adjuvant chemo- and radiotherapy167 (73%)
 None31 (14%)
No preoperative dexamethasone—N (%)2 (0.8%)
Preoperative dexamethasone228 (99.2%)
Postoperative dexamethasone229 (99%)
Preoperative dexamethasone—median mg (IQR)12 (4–16)
Postoperative dexamethasone11.9 (9.3–14.5)
Length of hospital stay (median days IQR), N8 (4–17), 222
Time to recurrence 263 (133–387), 57
Time to progression124.5 (82–201), 80
Time to infection69 (19.5–112), 58
Time to thrombosis60 (30–137), 41
Time to death254 (133–457), 199
NLR measurements (median IQR), N
Perioperative NLR9 (5–16), 230
Postoperative NLR11 (6–19), 169
Positive Δ NLR6 (2–12), 94
Patient Characteristics
Age at diagnosis mean ± SD, N 64.4 ± 11.8, 230
Female sex—n (%)88 (36%)
BMI mean ± SD, N 26.0 ± 5.1, 179
Tumor MGMT promoter methylation—n (%), N90 (42%), 217
KPS score at presentation—n (%), N
≥70%150 (65%), 230
<70%80 (35%)
Surgery type—n (%), N
 Biopsy only57 (25%), 230
 Partial resection98 (43%)
 Complete resection75 (33%)
Adjuvant therapy received—N (%), N
 Adjuvant chemotherapy only15 (7%), 228
 Adjuvant radiotherapy only15 (7%)
 Adjuvant chemo- and radiotherapy167 (73%)
 None31 (14%)
No preoperative dexamethasone—N (%)2 (0.8%)
Preoperative dexamethasone228 (99.2%)
Postoperative dexamethasone229 (99%)
Preoperative dexamethasone—median mg (IQR)12 (4–16)
Postoperative dexamethasone11.9 (9.3–14.5)
Length of hospital stay (median days IQR), N8 (4–17), 222
Time to recurrence 263 (133–387), 57
Time to progression124.5 (82–201), 80
Time to infection69 (19.5–112), 58
Time to thrombosis60 (30–137), 41
Time to death254 (133–457), 199
NLR measurements (median IQR), N
Perioperative NLR9 (5–16), 230
Postoperative NLR11 (6–19), 169
Positive Δ NLR6 (2–12), 94

Abbreviations: BMI:, body mass index; IQR, interquartile range; KPS, Karnofsky Performance Scale; MGMT: O6-methylguanine-DNA methyltransferase; NLR, neutrophil-to-lymphocyte ratio; SD, standard deviation.

ΔNLR signifies a change in NLR from preoperative to postoperative NLR values = postoperative NLR—preoperative NLR.

Table 1.

Patient Cohort Characteristics

Patient Characteristics
Age at diagnosis mean ± SD, N 64.4 ± 11.8, 230
Female sex—n (%)88 (36%)
BMI mean ± SD, N 26.0 ± 5.1, 179
Tumor MGMT promoter methylation—n (%), N90 (42%), 217
KPS score at presentation—n (%), N
≥70%150 (65%), 230
<70%80 (35%)
Surgery type—n (%), N
 Biopsy only57 (25%), 230
 Partial resection98 (43%)
 Complete resection75 (33%)
Adjuvant therapy received—N (%), N
 Adjuvant chemotherapy only15 (7%), 228
 Adjuvant radiotherapy only15 (7%)
 Adjuvant chemo- and radiotherapy167 (73%)
 None31 (14%)
No preoperative dexamethasone—N (%)2 (0.8%)
Preoperative dexamethasone228 (99.2%)
Postoperative dexamethasone229 (99%)
Preoperative dexamethasone—median mg (IQR)12 (4–16)
Postoperative dexamethasone11.9 (9.3–14.5)
Length of hospital stay (median days IQR), N8 (4–17), 222
Time to recurrence 263 (133–387), 57
Time to progression124.5 (82–201), 80
Time to infection69 (19.5–112), 58
Time to thrombosis60 (30–137), 41
Time to death254 (133–457), 199
NLR measurements (median IQR), N
Perioperative NLR9 (5–16), 230
Postoperative NLR11 (6–19), 169
Positive Δ NLR6 (2–12), 94
Patient Characteristics
Age at diagnosis mean ± SD, N 64.4 ± 11.8, 230
Female sex—n (%)88 (36%)
BMI mean ± SD, N 26.0 ± 5.1, 179
Tumor MGMT promoter methylation—n (%), N90 (42%), 217
KPS score at presentation—n (%), N
≥70%150 (65%), 230
<70%80 (35%)
Surgery type—n (%), N
 Biopsy only57 (25%), 230
 Partial resection98 (43%)
 Complete resection75 (33%)
Adjuvant therapy received—N (%), N
 Adjuvant chemotherapy only15 (7%), 228
 Adjuvant radiotherapy only15 (7%)
 Adjuvant chemo- and radiotherapy167 (73%)
 None31 (14%)
No preoperative dexamethasone—N (%)2 (0.8%)
Preoperative dexamethasone228 (99.2%)
Postoperative dexamethasone229 (99%)
Preoperative dexamethasone—median mg (IQR)12 (4–16)
Postoperative dexamethasone11.9 (9.3–14.5)
Length of hospital stay (median days IQR), N8 (4–17), 222
Time to recurrence 263 (133–387), 57
Time to progression124.5 (82–201), 80
Time to infection69 (19.5–112), 58
Time to thrombosis60 (30–137), 41
Time to death254 (133–457), 199
NLR measurements (median IQR), N
Perioperative NLR9 (5–16), 230
Postoperative NLR11 (6–19), 169
Positive Δ NLR6 (2–12), 94

Abbreviations: BMI:, body mass index; IQR, interquartile range; KPS, Karnofsky Performance Scale; MGMT: O6-methylguanine-DNA methyltransferase; NLR, neutrophil-to-lymphocyte ratio; SD, standard deviation.

ΔNLR signifies a change in NLR from preoperative to postoperative NLR values = postoperative NLR—preoperative NLR.

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