Variables Linked to Anal Squamous Intraepithelial Lesion Subsequent to the Completion of the Screening Cascade Among Individuals Engaged in Anal Cancer Screening
| Characteristic . | Anal Squamous Intraepithelial Lesion . | Unadjusted OR . | P Value . | Adjusted OR . | P Value . | |
|---|---|---|---|---|---|---|
| No n, (%) . | Yes n, (%) . | |||||
| Age | ||||||
| <50 | 106 (74.6) | 36 (25.4) | Ref. | |||
| 50–70 | 172 (78.9) | 46 (21.1) | 0.79 (0.48–1.30) | .347 | ||
| >70 | 6 (75.0) | 2 (25.0) | 1.03 (0.13–4.87) | .982 | ||
| Gender | ||||||
| Female | 48 (92.3) | 4 (7.7) | Ref. | |||
| Male | 236 (74.7) | 80 (25.3) | 3.92 (1.53–13.6) | .005 | 3.37 (1.27–11.77) | .029 |
| Smoking status | ||||||
| Never | 172 (78.9) | 46 (21.1) | Ref. | |||
| Former/current | 104 (75.9) | 33 (24.1) | 1.19 (0.71–1.97) | .510 | ||
| Current CD4 cells/uL | ||||||
| >500 | 218 (80.4) | 53 (19.4) | Ref. | |||
| 350–500 | 40 (81.6) | 9 (18.4) | 0.94 (0.40–1.98) | .846 | 0.83 (0.35–1.79) | .648 |
| <350 | 13 (59.1) | 9 (40.9) | 2.85 (1.11–7.03) | .018 | 2.95 (1.09–7.81) | .028 |
| CD4/CD8 ratio | ||||||
| >1 | 111 (87.4) | 16 (12.6) | Ref. | |||
| <1 | 153 (74.6) | 52 (25.4) | 2.34 (1.29–4.44) | .005 | 2.09 (1.13–4.05) | .021 |
| Nadir CD4 count, cells/uL | ||||||
| >350 | 62 (82.7) | 13 (17.3) | Ref. | |||
| 200–350 | 58 (79.5) | 15 (20.5) | 1.23 (0.53–2.86) | .618 | ||
| <200 | 63 (75.9) | 20 (24.1) | 1.50 (0.69–3.38) | .296 | ||
| Characteristic . | Anal Squamous Intraepithelial Lesion . | Unadjusted OR . | P Value . | Adjusted OR . | P Value . | |
|---|---|---|---|---|---|---|
| No n, (%) . | Yes n, (%) . | |||||
| Age | ||||||
| <50 | 106 (74.6) | 36 (25.4) | Ref. | |||
| 50–70 | 172 (78.9) | 46 (21.1) | 0.79 (0.48–1.30) | .347 | ||
| >70 | 6 (75.0) | 2 (25.0) | 1.03 (0.13–4.87) | .982 | ||
| Gender | ||||||
| Female | 48 (92.3) | 4 (7.7) | Ref. | |||
| Male | 236 (74.7) | 80 (25.3) | 3.92 (1.53–13.6) | .005 | 3.37 (1.27–11.77) | .029 |
| Smoking status | ||||||
| Never | 172 (78.9) | 46 (21.1) | Ref. | |||
| Former/current | 104 (75.9) | 33 (24.1) | 1.19 (0.71–1.97) | .510 | ||
| Current CD4 cells/uL | ||||||
| >500 | 218 (80.4) | 53 (19.4) | Ref. | |||
| 350–500 | 40 (81.6) | 9 (18.4) | 0.94 (0.40–1.98) | .846 | 0.83 (0.35–1.79) | .648 |
| <350 | 13 (59.1) | 9 (40.9) | 2.85 (1.11–7.03) | .018 | 2.95 (1.09–7.81) | .028 |
| CD4/CD8 ratio | ||||||
| >1 | 111 (87.4) | 16 (12.6) | Ref. | |||
| <1 | 153 (74.6) | 52 (25.4) | 2.34 (1.29–4.44) | .005 | 2.09 (1.13–4.05) | .021 |
| Nadir CD4 count, cells/uL | ||||||
| >350 | 62 (82.7) | 13 (17.3) | Ref. | |||
| 200–350 | 58 (79.5) | 15 (20.5) | 1.23 (0.53–2.86) | .618 | ||
| <200 | 63 (75.9) | 20 (24.1) | 1.50 (0.69–3.38) | .296 | ||
Abbreviation: OR, odds ratio.
Variables Linked to Anal Squamous Intraepithelial Lesion Subsequent to the Completion of the Screening Cascade Among Individuals Engaged in Anal Cancer Screening
| Characteristic . | Anal Squamous Intraepithelial Lesion . | Unadjusted OR . | P Value . | Adjusted OR . | P Value . | |
|---|---|---|---|---|---|---|
| No n, (%) . | Yes n, (%) . | |||||
| Age | ||||||
| <50 | 106 (74.6) | 36 (25.4) | Ref. | |||
| 50–70 | 172 (78.9) | 46 (21.1) | 0.79 (0.48–1.30) | .347 | ||
| >70 | 6 (75.0) | 2 (25.0) | 1.03 (0.13–4.87) | .982 | ||
| Gender | ||||||
| Female | 48 (92.3) | 4 (7.7) | Ref. | |||
| Male | 236 (74.7) | 80 (25.3) | 3.92 (1.53–13.6) | .005 | 3.37 (1.27–11.77) | .029 |
| Smoking status | ||||||
| Never | 172 (78.9) | 46 (21.1) | Ref. | |||
| Former/current | 104 (75.9) | 33 (24.1) | 1.19 (0.71–1.97) | .510 | ||
| Current CD4 cells/uL | ||||||
| >500 | 218 (80.4) | 53 (19.4) | Ref. | |||
| 350–500 | 40 (81.6) | 9 (18.4) | 0.94 (0.40–1.98) | .846 | 0.83 (0.35–1.79) | .648 |
| <350 | 13 (59.1) | 9 (40.9) | 2.85 (1.11–7.03) | .018 | 2.95 (1.09–7.81) | .028 |
| CD4/CD8 ratio | ||||||
| >1 | 111 (87.4) | 16 (12.6) | Ref. | |||
| <1 | 153 (74.6) | 52 (25.4) | 2.34 (1.29–4.44) | .005 | 2.09 (1.13–4.05) | .021 |
| Nadir CD4 count, cells/uL | ||||||
| >350 | 62 (82.7) | 13 (17.3) | Ref. | |||
| 200–350 | 58 (79.5) | 15 (20.5) | 1.23 (0.53–2.86) | .618 | ||
| <200 | 63 (75.9) | 20 (24.1) | 1.50 (0.69–3.38) | .296 | ||
| Characteristic . | Anal Squamous Intraepithelial Lesion . | Unadjusted OR . | P Value . | Adjusted OR . | P Value . | |
|---|---|---|---|---|---|---|
| No n, (%) . | Yes n, (%) . | |||||
| Age | ||||||
| <50 | 106 (74.6) | 36 (25.4) | Ref. | |||
| 50–70 | 172 (78.9) | 46 (21.1) | 0.79 (0.48–1.30) | .347 | ||
| >70 | 6 (75.0) | 2 (25.0) | 1.03 (0.13–4.87) | .982 | ||
| Gender | ||||||
| Female | 48 (92.3) | 4 (7.7) | Ref. | |||
| Male | 236 (74.7) | 80 (25.3) | 3.92 (1.53–13.6) | .005 | 3.37 (1.27–11.77) | .029 |
| Smoking status | ||||||
| Never | 172 (78.9) | 46 (21.1) | Ref. | |||
| Former/current | 104 (75.9) | 33 (24.1) | 1.19 (0.71–1.97) | .510 | ||
| Current CD4 cells/uL | ||||||
| >500 | 218 (80.4) | 53 (19.4) | Ref. | |||
| 350–500 | 40 (81.6) | 9 (18.4) | 0.94 (0.40–1.98) | .846 | 0.83 (0.35–1.79) | .648 |
| <350 | 13 (59.1) | 9 (40.9) | 2.85 (1.11–7.03) | .018 | 2.95 (1.09–7.81) | .028 |
| CD4/CD8 ratio | ||||||
| >1 | 111 (87.4) | 16 (12.6) | Ref. | |||
| <1 | 153 (74.6) | 52 (25.4) | 2.34 (1.29–4.44) | .005 | 2.09 (1.13–4.05) | .021 |
| Nadir CD4 count, cells/uL | ||||||
| >350 | 62 (82.7) | 13 (17.3) | Ref. | |||
| 200–350 | 58 (79.5) | 15 (20.5) | 1.23 (0.53–2.86) | .618 | ||
| <200 | 63 (75.9) | 20 (24.1) | 1.50 (0.69–3.38) | .296 | ||
Abbreviation: OR, odds ratio.
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