Table 1:

Some key studies comparing outcomes of older patients on HD and PD.

  Study population (n) 
StudyAge of study participants (years)HDPDKey findings
North Thames Dialysis Study
Harris et al. [50]
>709678• No difference in mortality or QoL at 12 months
BOLDE study
Brown et al. [57]
>657070• QoL not statistically different between HD and PD cohorts
• Depression and feelings of illness intrusion significantly less in the PD cohort
ERA–EDTA Registry
van de Luijtgaarden et al. [54]
Multiple age categories, including
60–69 and >70
83471544• Survival better on PD in patients >70 years versus HD
• Increasing age associated with a lower likelihood of receiving PD, particularly in females
• Non-diabetic patients and those with malignancy less likely to receive PD, despite better survival rates
Foote et al. [52]>751328453• Median survival for the older person starting dialysis was 2.3 years
• Mortality risk increased with number of comorbidities and age
• Late referral and lack of prepared dialysis access were risk factors for poorer survival
Korean meta-analysis
Han et al. [55]
>6510 6752390• Higher mortality rate in PD cohort compared to HD (< .001)
• Survival benefit of HD in those with diabetes mellitus or dialysis duration >1 year
Wolfgram et al. [68]mean = 69.2112 9608663• Lower incidence of dementia in the PD cohort over 3 years
• Risk of dementia lower for people starting on PD
FEPOD study
Iyasere et al. [6]
>60122129
(assisted PD)
• No difference in QoL
• Higher treatment satisfaction scores for people on assisted PD compared to those on in-centre HD
Swedish Renal Registry
Rydell et al. [56]
>65118118
(assisted PD)
• No significant difference in number of days per year in hospital, number of hospitalizations, or discontinuation of dialysis modality between groups
• Worse survival on assisted PD, however likely due to use as a palliative treatment
• Assisted PD likely to be a reasonable alternative to HD in the frail, older population
  Study population (n) 
StudyAge of study participants (years)HDPDKey findings
North Thames Dialysis Study
Harris et al. [50]
>709678• No difference in mortality or QoL at 12 months
BOLDE study
Brown et al. [57]
>657070• QoL not statistically different between HD and PD cohorts
• Depression and feelings of illness intrusion significantly less in the PD cohort
ERA–EDTA Registry
van de Luijtgaarden et al. [54]
Multiple age categories, including
60–69 and >70
83471544• Survival better on PD in patients >70 years versus HD
• Increasing age associated with a lower likelihood of receiving PD, particularly in females
• Non-diabetic patients and those with malignancy less likely to receive PD, despite better survival rates
Foote et al. [52]>751328453• Median survival for the older person starting dialysis was 2.3 years
• Mortality risk increased with number of comorbidities and age
• Late referral and lack of prepared dialysis access were risk factors for poorer survival
Korean meta-analysis
Han et al. [55]
>6510 6752390• Higher mortality rate in PD cohort compared to HD (< .001)
• Survival benefit of HD in those with diabetes mellitus or dialysis duration >1 year
Wolfgram et al. [68]mean = 69.2112 9608663• Lower incidence of dementia in the PD cohort over 3 years
• Risk of dementia lower for people starting on PD
FEPOD study
Iyasere et al. [6]
>60122129
(assisted PD)
• No difference in QoL
• Higher treatment satisfaction scores for people on assisted PD compared to those on in-centre HD
Swedish Renal Registry
Rydell et al. [56]
>65118118
(assisted PD)
• No significant difference in number of days per year in hospital, number of hospitalizations, or discontinuation of dialysis modality between groups
• Worse survival on assisted PD, however likely due to use as a palliative treatment
• Assisted PD likely to be a reasonable alternative to HD in the frail, older population
Table 1:

Some key studies comparing outcomes of older patients on HD and PD.

  Study population (n) 
StudyAge of study participants (years)HDPDKey findings
North Thames Dialysis Study
Harris et al. [50]
>709678• No difference in mortality or QoL at 12 months
BOLDE study
Brown et al. [57]
>657070• QoL not statistically different between HD and PD cohorts
• Depression and feelings of illness intrusion significantly less in the PD cohort
ERA–EDTA Registry
van de Luijtgaarden et al. [54]
Multiple age categories, including
60–69 and >70
83471544• Survival better on PD in patients >70 years versus HD
• Increasing age associated with a lower likelihood of receiving PD, particularly in females
• Non-diabetic patients and those with malignancy less likely to receive PD, despite better survival rates
Foote et al. [52]>751328453• Median survival for the older person starting dialysis was 2.3 years
• Mortality risk increased with number of comorbidities and age
• Late referral and lack of prepared dialysis access were risk factors for poorer survival
Korean meta-analysis
Han et al. [55]
>6510 6752390• Higher mortality rate in PD cohort compared to HD (< .001)
• Survival benefit of HD in those with diabetes mellitus or dialysis duration >1 year
Wolfgram et al. [68]mean = 69.2112 9608663• Lower incidence of dementia in the PD cohort over 3 years
• Risk of dementia lower for people starting on PD
FEPOD study
Iyasere et al. [6]
>60122129
(assisted PD)
• No difference in QoL
• Higher treatment satisfaction scores for people on assisted PD compared to those on in-centre HD
Swedish Renal Registry
Rydell et al. [56]
>65118118
(assisted PD)
• No significant difference in number of days per year in hospital, number of hospitalizations, or discontinuation of dialysis modality between groups
• Worse survival on assisted PD, however likely due to use as a palliative treatment
• Assisted PD likely to be a reasonable alternative to HD in the frail, older population
  Study population (n) 
StudyAge of study participants (years)HDPDKey findings
North Thames Dialysis Study
Harris et al. [50]
>709678• No difference in mortality or QoL at 12 months
BOLDE study
Brown et al. [57]
>657070• QoL not statistically different between HD and PD cohorts
• Depression and feelings of illness intrusion significantly less in the PD cohort
ERA–EDTA Registry
van de Luijtgaarden et al. [54]
Multiple age categories, including
60–69 and >70
83471544• Survival better on PD in patients >70 years versus HD
• Increasing age associated with a lower likelihood of receiving PD, particularly in females
• Non-diabetic patients and those with malignancy less likely to receive PD, despite better survival rates
Foote et al. [52]>751328453• Median survival for the older person starting dialysis was 2.3 years
• Mortality risk increased with number of comorbidities and age
• Late referral and lack of prepared dialysis access were risk factors for poorer survival
Korean meta-analysis
Han et al. [55]
>6510 6752390• Higher mortality rate in PD cohort compared to HD (< .001)
• Survival benefit of HD in those with diabetes mellitus or dialysis duration >1 year
Wolfgram et al. [68]mean = 69.2112 9608663• Lower incidence of dementia in the PD cohort over 3 years
• Risk of dementia lower for people starting on PD
FEPOD study
Iyasere et al. [6]
>60122129
(assisted PD)
• No difference in QoL
• Higher treatment satisfaction scores for people on assisted PD compared to those on in-centre HD
Swedish Renal Registry
Rydell et al. [56]
>65118118
(assisted PD)
• No significant difference in number of days per year in hospital, number of hospitalizations, or discontinuation of dialysis modality between groups
• Worse survival on assisted PD, however likely due to use as a palliative treatment
• Assisted PD likely to be a reasonable alternative to HD in the frail, older population
Close
This Feature Is Available To Subscribers Only

Sign In or Create an Account

Close

This PDF is available to Subscribers Only

View Article Abstract & Purchase Options

For full access to this pdf, sign in to an existing account, or purchase an annual subscription.

Close