Baseline characteristics of the study population (n = 10 049) from the DanRisk and DANCAVAS studies stratified by age groups and sex
| . | Women . | Men . | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) . | ≤ 50 n = 81 . | 51 to ≤ 60 n = 292 . | 61 to ≤ 70 n = 487 . | 71 to ≤ 75 n = 98 . | ≤50 n = 66 . | 51 to ≤ 60 n = 596 . | 61 to ≤ 70 n = 6682 . | 71 to ≤ 75 n = 1747 . | ||||||||
| CAC score | ||||||||||||||||
| 0 | 63 | 77.8% | 227 | 77.7% | 251 | 51.5% | 30 | 30.6% | 34 | 51.5% | 265 | 44.5% | 1476 | 22.1% | 215 | 12.3% |
| > 0–< 10 | 9 | 11.1% | 32 | 11.0% | 48 | 9.9% | 15 | 15.3% | 16 | 24.2% | 75 | 12.6% | 725 | 10.9% | 134 | 7.7% |
| ≥10–< 100 | 8 | 9.9% | 20 | 6.8% | 117 | 24.0% | 26 | 26.5% | 9 | 13.6% | 133 | 22.3% | 1832 | 27.4% | 380 | 21.8% |
| ≥ 100–< 400 | 1 | 1.2% | 9 | 3.1% | 51 | 10.5% | 19 | 19.4% | 4 | 6.1% | 89 | 14.9% | 1519 | 22.7% | 517 | 29.6% |
| ≥400 | 0 | 0.0% | 4 | 1.4% | 20 | 4.1% | 8 | 8.2% | 3 | 4.6% | 34 | 5.7% | 1130 | 16.9% | 501 | 28.7% |
| Smoking | ||||||||||||||||
| Non-smokers | 46 | 56.8% | 131 | 44.9% | 247 | 50.7% | 60 | 61.2% | 28 | 42.4% | 239 | 40.1% | 2377 | 35.6% | 628 | 35.9% |
| Former smokers | 20 | 24.7% | 97 | 33.2% | 161 | 33.1% | 25 | 25.5% | 15 | 22.7% | 219 | 36.7% | 3181 | 47.6% | 914 | 52.3% |
| Active smokers | 15 | 18.5% | 64 | 21.9% | 79 | 16.2% | 13 | 13.3% | 23 | 34.8% | 138 | 23.2% | 1124 | 16.8% | 205 | 11.7% |
| BMI (kg/m2) | 26.2 | (5.5) | 26.2 | (4.6) | 26.2 | (5.0) | 25.9 | (5.5) | 25.9 | (3.3) | 27.6 | (4.5) | 27.6 | (4.1) | 27.3 | (3.9) |
| LDL-C (mmol/L) | 2.8 | (0.7) | 3.2 | (0.8) | 3.6 | (0.8) | 3.6 | (0.8) | 3.4 | (0.9) | 3.3 | (0.9) | 3.3 | (0.8) | 3.2 | (0.8) |
| HDL-C (mmol/L) | 1.6 | (0.4) | 1.7 | (0.5) | 1.7 | (0.5) | 1.7 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.5 | (0.4) |
| Triglycerides (mmol/L) | 1.2 | (0.6) | 1.3 | (0.9) | 1.6 | (0.9) | 1.8 | (0.9) | 1.7 | (1.0) | 1.8 | (1.2) | 1.8 | (1.1) | 1.7 | (0.9) |
| Total cholesterol (mmol/L) | 5.0 | (0.8) | 5.6 | (0.9) | 6.0 | (0.9) | 6.1 | (1.0) | 5.6 | (1.0) | 5.4 | (1.0) | 5.5 | (0.9) | 5.4 | (0.9) |
| Non-HDL-C (mmol/L)a | 3.4 | (0.8) | 3.9 | (1.0) | 4.3 | (1.0) | 4.4 | (1.0) | 4.2 | (1.1) | 4.0 | (1.0) | 4.0 | (1.0) | 3.9 | (0.9) |
| Hypercholesterolaemiab | 41 | 50.6% | 228 | 78.1% | 441 | 90.6% | 88 | 89.8% | 50 | 75.8% | 433 | 72.7% | 5092 | 76.2% | 1267 | 72.5% |
| Hypertensionc | 22 | 27.2% | 127 | 43.5% | 333 | 68.4% | 83 | 84.7% | 30 | 45.5% | 334 | 56.0% | 5000 | 74.8% | 1445 | 82.7% |
| Family history of CVD (yes) | 14 | 17.3% | 83 | 28.4% | 84 | 17.2% | 11 | 11.2% | 15 | 22.7% | 103 | 17.3% | 816 | 12.2% | 165 | 9.4% |
| Diabetesd | 2 | 2.5% | 5 | 1.7% | 11 | 2.3% | 8 | 8.2% | 1 | 1.5% | 18 | 3.0% | 308 | 4.6% | 108 | 6.2% |
| . | Women . | Men . | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) . | ≤ 50 n = 81 . | 51 to ≤ 60 n = 292 . | 61 to ≤ 70 n = 487 . | 71 to ≤ 75 n = 98 . | ≤50 n = 66 . | 51 to ≤ 60 n = 596 . | 61 to ≤ 70 n = 6682 . | 71 to ≤ 75 n = 1747 . | ||||||||
| CAC score | ||||||||||||||||
| 0 | 63 | 77.8% | 227 | 77.7% | 251 | 51.5% | 30 | 30.6% | 34 | 51.5% | 265 | 44.5% | 1476 | 22.1% | 215 | 12.3% |
| > 0–< 10 | 9 | 11.1% | 32 | 11.0% | 48 | 9.9% | 15 | 15.3% | 16 | 24.2% | 75 | 12.6% | 725 | 10.9% | 134 | 7.7% |
| ≥10–< 100 | 8 | 9.9% | 20 | 6.8% | 117 | 24.0% | 26 | 26.5% | 9 | 13.6% | 133 | 22.3% | 1832 | 27.4% | 380 | 21.8% |
| ≥ 100–< 400 | 1 | 1.2% | 9 | 3.1% | 51 | 10.5% | 19 | 19.4% | 4 | 6.1% | 89 | 14.9% | 1519 | 22.7% | 517 | 29.6% |
| ≥400 | 0 | 0.0% | 4 | 1.4% | 20 | 4.1% | 8 | 8.2% | 3 | 4.6% | 34 | 5.7% | 1130 | 16.9% | 501 | 28.7% |
| Smoking | ||||||||||||||||
| Non-smokers | 46 | 56.8% | 131 | 44.9% | 247 | 50.7% | 60 | 61.2% | 28 | 42.4% | 239 | 40.1% | 2377 | 35.6% | 628 | 35.9% |
| Former smokers | 20 | 24.7% | 97 | 33.2% | 161 | 33.1% | 25 | 25.5% | 15 | 22.7% | 219 | 36.7% | 3181 | 47.6% | 914 | 52.3% |
| Active smokers | 15 | 18.5% | 64 | 21.9% | 79 | 16.2% | 13 | 13.3% | 23 | 34.8% | 138 | 23.2% | 1124 | 16.8% | 205 | 11.7% |
| BMI (kg/m2) | 26.2 | (5.5) | 26.2 | (4.6) | 26.2 | (5.0) | 25.9 | (5.5) | 25.9 | (3.3) | 27.6 | (4.5) | 27.6 | (4.1) | 27.3 | (3.9) |
| LDL-C (mmol/L) | 2.8 | (0.7) | 3.2 | (0.8) | 3.6 | (0.8) | 3.6 | (0.8) | 3.4 | (0.9) | 3.3 | (0.9) | 3.3 | (0.8) | 3.2 | (0.8) |
| HDL-C (mmol/L) | 1.6 | (0.4) | 1.7 | (0.5) | 1.7 | (0.5) | 1.7 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.5 | (0.4) |
| Triglycerides (mmol/L) | 1.2 | (0.6) | 1.3 | (0.9) | 1.6 | (0.9) | 1.8 | (0.9) | 1.7 | (1.0) | 1.8 | (1.2) | 1.8 | (1.1) | 1.7 | (0.9) |
| Total cholesterol (mmol/L) | 5.0 | (0.8) | 5.6 | (0.9) | 6.0 | (0.9) | 6.1 | (1.0) | 5.6 | (1.0) | 5.4 | (1.0) | 5.5 | (0.9) | 5.4 | (0.9) |
| Non-HDL-C (mmol/L)a | 3.4 | (0.8) | 3.9 | (1.0) | 4.3 | (1.0) | 4.4 | (1.0) | 4.2 | (1.1) | 4.0 | (1.0) | 4.0 | (1.0) | 3.9 | (0.9) |
| Hypercholesterolaemiab | 41 | 50.6% | 228 | 78.1% | 441 | 90.6% | 88 | 89.8% | 50 | 75.8% | 433 | 72.7% | 5092 | 76.2% | 1267 | 72.5% |
| Hypertensionc | 22 | 27.2% | 127 | 43.5% | 333 | 68.4% | 83 | 84.7% | 30 | 45.5% | 334 | 56.0% | 5000 | 74.8% | 1445 | 82.7% |
| Family history of CVD (yes) | 14 | 17.3% | 83 | 28.4% | 84 | 17.2% | 11 | 11.2% | 15 | 22.7% | 103 | 17.3% | 816 | 12.2% | 165 | 9.4% |
| Diabetesd | 2 | 2.5% | 5 | 1.7% | 11 | 2.3% | 8 | 8.2% | 1 | 1.5% | 18 | 3.0% | 308 | 4.6% | 108 | 6.2% |
Numbers are n (%), mean (SD).
n, number of participants; BMI, body mass index; CAC, coronary artery calcification; CVD, cardiovascular disease; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.
aTotal blood cholesterol with HDL-C subtracted.
bBased on self-reported hypercholesterolaemia, or total cholesterol >5 mmol/L.
cBased on participants with one or more of the following criteria: systolic blood pressure ≥140 mmHg; diastolic blood pressure ≥90 mmHg; using antihypertensive medication.
dBased on self-reported diabetes, or a fasting plasma blood glucose level ≥7.0 mmol/L on two separate days.
Baseline characteristics of the study population (n = 10 049) from the DanRisk and DANCAVAS studies stratified by age groups and sex
| . | Women . | Men . | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) . | ≤ 50 n = 81 . | 51 to ≤ 60 n = 292 . | 61 to ≤ 70 n = 487 . | 71 to ≤ 75 n = 98 . | ≤50 n = 66 . | 51 to ≤ 60 n = 596 . | 61 to ≤ 70 n = 6682 . | 71 to ≤ 75 n = 1747 . | ||||||||
| CAC score | ||||||||||||||||
| 0 | 63 | 77.8% | 227 | 77.7% | 251 | 51.5% | 30 | 30.6% | 34 | 51.5% | 265 | 44.5% | 1476 | 22.1% | 215 | 12.3% |
| > 0–< 10 | 9 | 11.1% | 32 | 11.0% | 48 | 9.9% | 15 | 15.3% | 16 | 24.2% | 75 | 12.6% | 725 | 10.9% | 134 | 7.7% |
| ≥10–< 100 | 8 | 9.9% | 20 | 6.8% | 117 | 24.0% | 26 | 26.5% | 9 | 13.6% | 133 | 22.3% | 1832 | 27.4% | 380 | 21.8% |
| ≥ 100–< 400 | 1 | 1.2% | 9 | 3.1% | 51 | 10.5% | 19 | 19.4% | 4 | 6.1% | 89 | 14.9% | 1519 | 22.7% | 517 | 29.6% |
| ≥400 | 0 | 0.0% | 4 | 1.4% | 20 | 4.1% | 8 | 8.2% | 3 | 4.6% | 34 | 5.7% | 1130 | 16.9% | 501 | 28.7% |
| Smoking | ||||||||||||||||
| Non-smokers | 46 | 56.8% | 131 | 44.9% | 247 | 50.7% | 60 | 61.2% | 28 | 42.4% | 239 | 40.1% | 2377 | 35.6% | 628 | 35.9% |
| Former smokers | 20 | 24.7% | 97 | 33.2% | 161 | 33.1% | 25 | 25.5% | 15 | 22.7% | 219 | 36.7% | 3181 | 47.6% | 914 | 52.3% |
| Active smokers | 15 | 18.5% | 64 | 21.9% | 79 | 16.2% | 13 | 13.3% | 23 | 34.8% | 138 | 23.2% | 1124 | 16.8% | 205 | 11.7% |
| BMI (kg/m2) | 26.2 | (5.5) | 26.2 | (4.6) | 26.2 | (5.0) | 25.9 | (5.5) | 25.9 | (3.3) | 27.6 | (4.5) | 27.6 | (4.1) | 27.3 | (3.9) |
| LDL-C (mmol/L) | 2.8 | (0.7) | 3.2 | (0.8) | 3.6 | (0.8) | 3.6 | (0.8) | 3.4 | (0.9) | 3.3 | (0.9) | 3.3 | (0.8) | 3.2 | (0.8) |
| HDL-C (mmol/L) | 1.6 | (0.4) | 1.7 | (0.5) | 1.7 | (0.5) | 1.7 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.5 | (0.4) |
| Triglycerides (mmol/L) | 1.2 | (0.6) | 1.3 | (0.9) | 1.6 | (0.9) | 1.8 | (0.9) | 1.7 | (1.0) | 1.8 | (1.2) | 1.8 | (1.1) | 1.7 | (0.9) |
| Total cholesterol (mmol/L) | 5.0 | (0.8) | 5.6 | (0.9) | 6.0 | (0.9) | 6.1 | (1.0) | 5.6 | (1.0) | 5.4 | (1.0) | 5.5 | (0.9) | 5.4 | (0.9) |
| Non-HDL-C (mmol/L)a | 3.4 | (0.8) | 3.9 | (1.0) | 4.3 | (1.0) | 4.4 | (1.0) | 4.2 | (1.1) | 4.0 | (1.0) | 4.0 | (1.0) | 3.9 | (0.9) |
| Hypercholesterolaemiab | 41 | 50.6% | 228 | 78.1% | 441 | 90.6% | 88 | 89.8% | 50 | 75.8% | 433 | 72.7% | 5092 | 76.2% | 1267 | 72.5% |
| Hypertensionc | 22 | 27.2% | 127 | 43.5% | 333 | 68.4% | 83 | 84.7% | 30 | 45.5% | 334 | 56.0% | 5000 | 74.8% | 1445 | 82.7% |
| Family history of CVD (yes) | 14 | 17.3% | 83 | 28.4% | 84 | 17.2% | 11 | 11.2% | 15 | 22.7% | 103 | 17.3% | 816 | 12.2% | 165 | 9.4% |
| Diabetesd | 2 | 2.5% | 5 | 1.7% | 11 | 2.3% | 8 | 8.2% | 1 | 1.5% | 18 | 3.0% | 308 | 4.6% | 108 | 6.2% |
| . | Women . | Men . | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) . | ≤ 50 n = 81 . | 51 to ≤ 60 n = 292 . | 61 to ≤ 70 n = 487 . | 71 to ≤ 75 n = 98 . | ≤50 n = 66 . | 51 to ≤ 60 n = 596 . | 61 to ≤ 70 n = 6682 . | 71 to ≤ 75 n = 1747 . | ||||||||
| CAC score | ||||||||||||||||
| 0 | 63 | 77.8% | 227 | 77.7% | 251 | 51.5% | 30 | 30.6% | 34 | 51.5% | 265 | 44.5% | 1476 | 22.1% | 215 | 12.3% |
| > 0–< 10 | 9 | 11.1% | 32 | 11.0% | 48 | 9.9% | 15 | 15.3% | 16 | 24.2% | 75 | 12.6% | 725 | 10.9% | 134 | 7.7% |
| ≥10–< 100 | 8 | 9.9% | 20 | 6.8% | 117 | 24.0% | 26 | 26.5% | 9 | 13.6% | 133 | 22.3% | 1832 | 27.4% | 380 | 21.8% |
| ≥ 100–< 400 | 1 | 1.2% | 9 | 3.1% | 51 | 10.5% | 19 | 19.4% | 4 | 6.1% | 89 | 14.9% | 1519 | 22.7% | 517 | 29.6% |
| ≥400 | 0 | 0.0% | 4 | 1.4% | 20 | 4.1% | 8 | 8.2% | 3 | 4.6% | 34 | 5.7% | 1130 | 16.9% | 501 | 28.7% |
| Smoking | ||||||||||||||||
| Non-smokers | 46 | 56.8% | 131 | 44.9% | 247 | 50.7% | 60 | 61.2% | 28 | 42.4% | 239 | 40.1% | 2377 | 35.6% | 628 | 35.9% |
| Former smokers | 20 | 24.7% | 97 | 33.2% | 161 | 33.1% | 25 | 25.5% | 15 | 22.7% | 219 | 36.7% | 3181 | 47.6% | 914 | 52.3% |
| Active smokers | 15 | 18.5% | 64 | 21.9% | 79 | 16.2% | 13 | 13.3% | 23 | 34.8% | 138 | 23.2% | 1124 | 16.8% | 205 | 11.7% |
| BMI (kg/m2) | 26.2 | (5.5) | 26.2 | (4.6) | 26.2 | (5.0) | 25.9 | (5.5) | 25.9 | (3.3) | 27.6 | (4.5) | 27.6 | (4.1) | 27.3 | (3.9) |
| LDL-C (mmol/L) | 2.8 | (0.7) | 3.2 | (0.8) | 3.6 | (0.8) | 3.6 | (0.8) | 3.4 | (0.9) | 3.3 | (0.9) | 3.3 | (0.8) | 3.2 | (0.8) |
| HDL-C (mmol/L) | 1.6 | (0.4) | 1.7 | (0.5) | 1.7 | (0.5) | 1.7 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.4 | (0.4) | 1.5 | (0.4) |
| Triglycerides (mmol/L) | 1.2 | (0.6) | 1.3 | (0.9) | 1.6 | (0.9) | 1.8 | (0.9) | 1.7 | (1.0) | 1.8 | (1.2) | 1.8 | (1.1) | 1.7 | (0.9) |
| Total cholesterol (mmol/L) | 5.0 | (0.8) | 5.6 | (0.9) | 6.0 | (0.9) | 6.1 | (1.0) | 5.6 | (1.0) | 5.4 | (1.0) | 5.5 | (0.9) | 5.4 | (0.9) |
| Non-HDL-C (mmol/L)a | 3.4 | (0.8) | 3.9 | (1.0) | 4.3 | (1.0) | 4.4 | (1.0) | 4.2 | (1.1) | 4.0 | (1.0) | 4.0 | (1.0) | 3.9 | (0.9) |
| Hypercholesterolaemiab | 41 | 50.6% | 228 | 78.1% | 441 | 90.6% | 88 | 89.8% | 50 | 75.8% | 433 | 72.7% | 5092 | 76.2% | 1267 | 72.5% |
| Hypertensionc | 22 | 27.2% | 127 | 43.5% | 333 | 68.4% | 83 | 84.7% | 30 | 45.5% | 334 | 56.0% | 5000 | 74.8% | 1445 | 82.7% |
| Family history of CVD (yes) | 14 | 17.3% | 83 | 28.4% | 84 | 17.2% | 11 | 11.2% | 15 | 22.7% | 103 | 17.3% | 816 | 12.2% | 165 | 9.4% |
| Diabetesd | 2 | 2.5% | 5 | 1.7% | 11 | 2.3% | 8 | 8.2% | 1 | 1.5% | 18 | 3.0% | 308 | 4.6% | 108 | 6.2% |
Numbers are n (%), mean (SD).
n, number of participants; BMI, body mass index; CAC, coronary artery calcification; CVD, cardiovascular disease; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.
aTotal blood cholesterol with HDL-C subtracted.
bBased on self-reported hypercholesterolaemia, or total cholesterol >5 mmol/L.
cBased on participants with one or more of the following criteria: systolic blood pressure ≥140 mmHg; diastolic blood pressure ≥90 mmHg; using antihypertensive medication.
dBased on self-reported diabetes, or a fasting plasma blood glucose level ≥7.0 mmol/L on two separate days.
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