Table 1

Changes in mother’s LDL-C values according to modification of lipid-lowering therapy

 LDL-C (mg/dL)
No lipid-lowering therapy at HeFH diagnosis (44 weeks before the start of gestation)364
High-intensity statin plus ezetimibe (25 weeks before the start of gestation)191
Three months after the first injection of inclisiran (13 weeks before the start of gestation)103
No lipid-lowering therapy (soon after the child’s birth)391
Three months after the complete resumption of lipid-lowering treatment (8 months after the child’s birth)75
 LDL-C (mg/dL)
No lipid-lowering therapy at HeFH diagnosis (44 weeks before the start of gestation)364
High-intensity statin plus ezetimibe (25 weeks before the start of gestation)191
Three months after the first injection of inclisiran (13 weeks before the start of gestation)103
No lipid-lowering therapy (soon after the child’s birth)391
Three months after the complete resumption of lipid-lowering treatment (8 months after the child’s birth)75

LDL-C, LDL cholesterol; HeFH, heterozygous familial hypercholesterolaemia.

Table 1

Changes in mother’s LDL-C values according to modification of lipid-lowering therapy

 LDL-C (mg/dL)
No lipid-lowering therapy at HeFH diagnosis (44 weeks before the start of gestation)364
High-intensity statin plus ezetimibe (25 weeks before the start of gestation)191
Three months after the first injection of inclisiran (13 weeks before the start of gestation)103
No lipid-lowering therapy (soon after the child’s birth)391
Three months after the complete resumption of lipid-lowering treatment (8 months after the child’s birth)75
 LDL-C (mg/dL)
No lipid-lowering therapy at HeFH diagnosis (44 weeks before the start of gestation)364
High-intensity statin plus ezetimibe (25 weeks before the start of gestation)191
Three months after the first injection of inclisiran (13 weeks before the start of gestation)103
No lipid-lowering therapy (soon after the child’s birth)391
Three months after the complete resumption of lipid-lowering treatment (8 months after the child’s birth)75

LDL-C, LDL cholesterol; HeFH, heterozygous familial hypercholesterolaemia.

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