Table 1.

Sample characteristics of participants across rs-fMRI studies.

AuthorsYearParticipant groups and sample sizesState of disease activity for IBD participants
ActiveRemitted/Inactive
Crohn’s disease
Huang et al.2024CD active (62), CD remitted (59), HC (91)YesYes
Sun et al.2024CD with anxiety or depression (33), CD without anxiety or depression (31), HC (29)NoYes
Thapaliya et al.2023CD (25), HC (25)YesNo
Chen et al.2023CD with pain (24), CD without pain (24), HC (28)NoYes
Agostini et al.2023CD active (19), CD remitted (14), HC (18)YesYes
Li et al.2022CD (20), HC (22)YesaNA
Qiu et al.2022CD (22), HC (22)YesaYes
Zhang et al.2022CD (45), HC (40)NoYes
Huang et al.2022CD active (58), CD inactive (57), HC (91)YesYes
Kong et al.2022CD (34), HC (20)YesYes
Li et al.2021CD (15), HC (26)NoYes
Kornelsen et al.2020CD (35), HC (21)YesYes
Fan et al.2020CD (42), HC (35)NoYes
Hou et al.2019CD (18), HC (18)NoYes
Bao at al.2018CD (60), HC (40)NoYes
Liu et al.2018CD (43), HC (37)NoYes
Thomann et al.2017CD (15), HC (14)NoYes
Bao et al.2016CD with pain (25), CD without pain (25), HC (32)NoYes
Ulcerative colitis
Wang et al.2022UC, IBS, and HC, n = 74 each)aYesYes
Kornelsen et al.2021UC (76), HC (74)aYesYes
Fan et al.2019UC (41), HC (42)YesNo
IBD combined
Wang et al.2023IBD (combined; subtype not specified: 37), HC (32)YesNo
Deng et al.2023IBD (combined; subtype not specified: 27), HC (29)NoYes
Goodyear et al.2023IBD (26 CD | 9 UC), HC (32)YesYes
Kornelsen et al.2022IBD (CD 35, UC 76), HC (74)YesYes
Prub et al.2022IBD patients with chronic abdominal pain (32; CD 26 | UC 6), HC (32)aYesYes
Thomann et al.2021IBD patients (31; CD 19 | UC 12), HC (13)NoYes
AuthorsYearParticipant groups and sample sizesState of disease activity for IBD participants
ActiveRemitted/Inactive
Crohn’s disease
Huang et al.2024CD active (62), CD remitted (59), HC (91)YesYes
Sun et al.2024CD with anxiety or depression (33), CD without anxiety or depression (31), HC (29)NoYes
Thapaliya et al.2023CD (25), HC (25)YesNo
Chen et al.2023CD with pain (24), CD without pain (24), HC (28)NoYes
Agostini et al.2023CD active (19), CD remitted (14), HC (18)YesYes
Li et al.2022CD (20), HC (22)YesaNA
Qiu et al.2022CD (22), HC (22)YesaYes
Zhang et al.2022CD (45), HC (40)NoYes
Huang et al.2022CD active (58), CD inactive (57), HC (91)YesYes
Kong et al.2022CD (34), HC (20)YesYes
Li et al.2021CD (15), HC (26)NoYes
Kornelsen et al.2020CD (35), HC (21)YesYes
Fan et al.2020CD (42), HC (35)NoYes
Hou et al.2019CD (18), HC (18)NoYes
Bao at al.2018CD (60), HC (40)NoYes
Liu et al.2018CD (43), HC (37)NoYes
Thomann et al.2017CD (15), HC (14)NoYes
Bao et al.2016CD with pain (25), CD without pain (25), HC (32)NoYes
Ulcerative colitis
Wang et al.2022UC, IBS, and HC, n = 74 each)aYesYes
Kornelsen et al.2021UC (76), HC (74)aYesYes
Fan et al.2019UC (41), HC (42)YesNo
IBD combined
Wang et al.2023IBD (combined; subtype not specified: 37), HC (32)YesNo
Deng et al.2023IBD (combined; subtype not specified: 27), HC (29)NoYes
Goodyear et al.2023IBD (26 CD | 9 UC), HC (32)YesYes
Kornelsen et al.2022IBD (CD 35, UC 76), HC (74)YesYes
Prub et al.2022IBD patients with chronic abdominal pain (32; CD 26 | UC 6), HC (32)aYesYes
Thomann et al.2021IBD patients (31; CD 19 | UC 12), HC (13)NoYes

Studies comparing resting-state pre–post intervention are not listed above.

aAssumed inclusion in a sample based on the presentation of means and standard deviations of continuous variables for assessing disease activity.

Abbreviations: CD = Crohn’s disease; HC = healthy controls; UC = ulcerative colitis.

Table 1.

Sample characteristics of participants across rs-fMRI studies.

AuthorsYearParticipant groups and sample sizesState of disease activity for IBD participants
ActiveRemitted/Inactive
Crohn’s disease
Huang et al.2024CD active (62), CD remitted (59), HC (91)YesYes
Sun et al.2024CD with anxiety or depression (33), CD without anxiety or depression (31), HC (29)NoYes
Thapaliya et al.2023CD (25), HC (25)YesNo
Chen et al.2023CD with pain (24), CD without pain (24), HC (28)NoYes
Agostini et al.2023CD active (19), CD remitted (14), HC (18)YesYes
Li et al.2022CD (20), HC (22)YesaNA
Qiu et al.2022CD (22), HC (22)YesaYes
Zhang et al.2022CD (45), HC (40)NoYes
Huang et al.2022CD active (58), CD inactive (57), HC (91)YesYes
Kong et al.2022CD (34), HC (20)YesYes
Li et al.2021CD (15), HC (26)NoYes
Kornelsen et al.2020CD (35), HC (21)YesYes
Fan et al.2020CD (42), HC (35)NoYes
Hou et al.2019CD (18), HC (18)NoYes
Bao at al.2018CD (60), HC (40)NoYes
Liu et al.2018CD (43), HC (37)NoYes
Thomann et al.2017CD (15), HC (14)NoYes
Bao et al.2016CD with pain (25), CD without pain (25), HC (32)NoYes
Ulcerative colitis
Wang et al.2022UC, IBS, and HC, n = 74 each)aYesYes
Kornelsen et al.2021UC (76), HC (74)aYesYes
Fan et al.2019UC (41), HC (42)YesNo
IBD combined
Wang et al.2023IBD (combined; subtype not specified: 37), HC (32)YesNo
Deng et al.2023IBD (combined; subtype not specified: 27), HC (29)NoYes
Goodyear et al.2023IBD (26 CD | 9 UC), HC (32)YesYes
Kornelsen et al.2022IBD (CD 35, UC 76), HC (74)YesYes
Prub et al.2022IBD patients with chronic abdominal pain (32; CD 26 | UC 6), HC (32)aYesYes
Thomann et al.2021IBD patients (31; CD 19 | UC 12), HC (13)NoYes
AuthorsYearParticipant groups and sample sizesState of disease activity for IBD participants
ActiveRemitted/Inactive
Crohn’s disease
Huang et al.2024CD active (62), CD remitted (59), HC (91)YesYes
Sun et al.2024CD with anxiety or depression (33), CD without anxiety or depression (31), HC (29)NoYes
Thapaliya et al.2023CD (25), HC (25)YesNo
Chen et al.2023CD with pain (24), CD without pain (24), HC (28)NoYes
Agostini et al.2023CD active (19), CD remitted (14), HC (18)YesYes
Li et al.2022CD (20), HC (22)YesaNA
Qiu et al.2022CD (22), HC (22)YesaYes
Zhang et al.2022CD (45), HC (40)NoYes
Huang et al.2022CD active (58), CD inactive (57), HC (91)YesYes
Kong et al.2022CD (34), HC (20)YesYes
Li et al.2021CD (15), HC (26)NoYes
Kornelsen et al.2020CD (35), HC (21)YesYes
Fan et al.2020CD (42), HC (35)NoYes
Hou et al.2019CD (18), HC (18)NoYes
Bao at al.2018CD (60), HC (40)NoYes
Liu et al.2018CD (43), HC (37)NoYes
Thomann et al.2017CD (15), HC (14)NoYes
Bao et al.2016CD with pain (25), CD without pain (25), HC (32)NoYes
Ulcerative colitis
Wang et al.2022UC, IBS, and HC, n = 74 each)aYesYes
Kornelsen et al.2021UC (76), HC (74)aYesYes
Fan et al.2019UC (41), HC (42)YesNo
IBD combined
Wang et al.2023IBD (combined; subtype not specified: 37), HC (32)YesNo
Deng et al.2023IBD (combined; subtype not specified: 27), HC (29)NoYes
Goodyear et al.2023IBD (26 CD | 9 UC), HC (32)YesYes
Kornelsen et al.2022IBD (CD 35, UC 76), HC (74)YesYes
Prub et al.2022IBD patients with chronic abdominal pain (32; CD 26 | UC 6), HC (32)aYesYes
Thomann et al.2021IBD patients (31; CD 19 | UC 12), HC (13)NoYes

Studies comparing resting-state pre–post intervention are not listed above.

aAssumed inclusion in a sample based on the presentation of means and standard deviations of continuous variables for assessing disease activity.

Abbreviations: CD = Crohn’s disease; HC = healthy controls; UC = ulcerative colitis.

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