| Score . | Predictor (95% CI), %a . | |||
|---|---|---|---|---|
| Viral Peak . | Time to Rebound . | Time to Peak . | Rate of Viral Replication . | |
| Sensitivity | 93 (82–98) | 96 (85–99) | 91 (79–96) | 98 (88–99) |
| Specificity | 73 (48–89) | 40 (20–64) | 40 (20–64) | 33 (15–58) |
| Accuracy | 88 (78–94) | 82 (70–89) | 78 (66–87) | 82 (70–89) |
| PPV | 91 (80–97) | 83 (70–91) | 82 (69–90) | 81 (69–90) |
| NPV | 79 (52–92) | 75 (41–93) | 60 (31–83) | 83 (44–97) |
| Prevalence | 75 (63–84) | 75 (63–84) | 75 (63–84) | 75 (63–84) |
| Score . | Predictor (95% CI), %a . | |||
|---|---|---|---|---|
| Viral Peak . | Time to Rebound . | Time to Peak . | Rate of Viral Replication . | |
| Sensitivity | 93 (82–98) | 96 (85–99) | 91 (79–96) | 98 (88–99) |
| Specificity | 73 (48–89) | 40 (20–64) | 40 (20–64) | 33 (15–58) |
| Accuracy | 88 (78–94) | 82 (70–89) | 78 (66–87) | 82 (70–89) |
| PPV | 91 (80–97) | 83 (70–91) | 82 (69–90) | 81 (69–90) |
| NPV | 79 (52–92) | 75 (41–93) | 60 (31–83) | 83 (44–97) |
| Prevalence | 75 (63–84) | 75 (63–84) | 75 (63–84) | 75 (63–84) |
Abbreviations: CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value.
aThe viral peak (plasma viremia) provides the highest predictive scores. Time to viral rebound, time to peak, and speed of viral rebound produce higher sensitivities than plasma viremia in classifying noncontrollers. However, these poorly classify controllers (with specificities <41%).
| Score . | Predictor (95% CI), %a . | |||
|---|---|---|---|---|
| Viral Peak . | Time to Rebound . | Time to Peak . | Rate of Viral Replication . | |
| Sensitivity | 93 (82–98) | 96 (85–99) | 91 (79–96) | 98 (88–99) |
| Specificity | 73 (48–89) | 40 (20–64) | 40 (20–64) | 33 (15–58) |
| Accuracy | 88 (78–94) | 82 (70–89) | 78 (66–87) | 82 (70–89) |
| PPV | 91 (80–97) | 83 (70–91) | 82 (69–90) | 81 (69–90) |
| NPV | 79 (52–92) | 75 (41–93) | 60 (31–83) | 83 (44–97) |
| Prevalence | 75 (63–84) | 75 (63–84) | 75 (63–84) | 75 (63–84) |
| Score . | Predictor (95% CI), %a . | |||
|---|---|---|---|---|
| Viral Peak . | Time to Rebound . | Time to Peak . | Rate of Viral Replication . | |
| Sensitivity | 93 (82–98) | 96 (85–99) | 91 (79–96) | 98 (88–99) |
| Specificity | 73 (48–89) | 40 (20–64) | 40 (20–64) | 33 (15–58) |
| Accuracy | 88 (78–94) | 82 (70–89) | 78 (66–87) | 82 (70–89) |
| PPV | 91 (80–97) | 83 (70–91) | 82 (69–90) | 81 (69–90) |
| NPV | 79 (52–92) | 75 (41–93) | 60 (31–83) | 83 (44–97) |
| Prevalence | 75 (63–84) | 75 (63–84) | 75 (63–84) | 75 (63–84) |
Abbreviations: CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value.
aThe viral peak (plasma viremia) provides the highest predictive scores. Time to viral rebound, time to peak, and speed of viral rebound produce higher sensitivities than plasma viremia in classifying noncontrollers. However, these poorly classify controllers (with specificities <41%).
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