| . | beta . | 95% CI . | P-value . |
|---|---|---|---|
| Ser539Trp | −2.33 | −2.52, −2.15 | 2.50E-140 |
| Asp563Gly | −0.98 | −1.04, −0.92 | 1.12E-225 |
| . | beta . | 95% CI . | P-value . |
|---|---|---|---|
| Ser539Trp | −2.33 | −2.52, −2.15 | 2.50E-140 |
| Asp563Gly | −0.98 | −1.04, −0.92 | 1.12E-225 |
The table shows the estimates resulting from the meta-analysis of the associations of LoF variants with PAM-AMA in the MDC-CC and in the MPP cohort. The results for the linear regression are adjusted for age, sex, and the first 10 genetic principal components. PAM-AMA is expressed in standardized units.
Abbreviations: CI, confidence interval; LoF, loss-of-function; MDC-CC, MDC-CC: Malmö Diet and Cancer-Cardiovascular cohort; MPP, Malmö Preventive Project cohort; PAM-AMA, peptidylglycine-α-amidating monooxygenase amidating activity.
| . | beta . | 95% CI . | P-value . |
|---|---|---|---|
| Ser539Trp | −2.33 | −2.52, −2.15 | 2.50E-140 |
| Asp563Gly | −0.98 | −1.04, −0.92 | 1.12E-225 |
| . | beta . | 95% CI . | P-value . |
|---|---|---|---|
| Ser539Trp | −2.33 | −2.52, −2.15 | 2.50E-140 |
| Asp563Gly | −0.98 | −1.04, −0.92 | 1.12E-225 |
The table shows the estimates resulting from the meta-analysis of the associations of LoF variants with PAM-AMA in the MDC-CC and in the MPP cohort. The results for the linear regression are adjusted for age, sex, and the first 10 genetic principal components. PAM-AMA is expressed in standardized units.
Abbreviations: CI, confidence interval; LoF, loss-of-function; MDC-CC, MDC-CC: Malmö Diet and Cancer-Cardiovascular cohort; MPP, Malmö Preventive Project cohort; PAM-AMA, peptidylglycine-α-amidating monooxygenase amidating activity.
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