Table 3.

Clinical Factors Associated With Shigella Diarrhea

Variable/ResponseParticipants, No. (%)aCrude OR (95% CI)P ValueaOR (95% CI)bP Value
Shigella Positive With Diarrhea (n = 67)Shigella Negative With Diarrhea (n = 4380)
Age, median (range), y5 (1–56)6 (0–76).411.00 (.98–1.01).61
Female respondent37 (55.2)2204 (50.3)1.22 (.75–1.98).431.25 (.77–2.03).32
Fever in past 3 d55 (82.1)2926 (66.8)2.28 (1.22–4.27).008c1.85 (.95–3.63).07
Vomiting29 (43.3)2220 (50.7)0.74 (.46–1.21).23
Abdominal pain51 (76.1)3196 (73.0)1.18 (.67–2.08).56
Distension2 (3.0)341 (7.8)0.36 (.09–1.50).14
Bloody diarrhea17 (25.4)322 (7.4)4.29 (2.44–7.52)<.001c
Constipation2 (3.0)104 (2.4)1.27 (.31–5.24).74
Headache27 (40.3)1629 (37.2)1.14 (.70–1.86).60
HIV/AIDS1 (1.5)50 (1.1)1.31 (.18–9.64).79
No medication in last 8 wk42 (62.7)2260 (51.6)0.64 (.40–1.05).07
Severe/moderate dehydration3 (4.5)59 (1.3)3.30 (1.01–10.82).049c
Mild dehydration5 (7.5)493 (11.3)0.66 (.26–1.65).37
Coated tongue1 (1.5)8 (0.2)8.28 (1.02–67.15).02c6.11 (.73–51.02).10
Tenderness/rebound tenderness3 (4.5)122 (2.8)1.64 (.51–5.28).41
dCurrent high fever14 (20.9)436 (10.0)2.64 (1.42–4.92).002c2.02 (1.04–3.94).04c
eCurrent low fever15 (22.4)812 (18.5)1.52 (.83–2.78).171.21 (.64–2.28).56
Variable/ResponseParticipants, No. (%)aCrude OR (95% CI)P ValueaOR (95% CI)bP Value
Shigella Positive With Diarrhea (n = 67)Shigella Negative With Diarrhea (n = 4380)
Age, median (range), y5 (1–56)6 (0–76).411.00 (.98–1.01).61
Female respondent37 (55.2)2204 (50.3)1.22 (.75–1.98).431.25 (.77–2.03).32
Fever in past 3 d55 (82.1)2926 (66.8)2.28 (1.22–4.27).008c1.85 (.95–3.63).07
Vomiting29 (43.3)2220 (50.7)0.74 (.46–1.21).23
Abdominal pain51 (76.1)3196 (73.0)1.18 (.67–2.08).56
Distension2 (3.0)341 (7.8)0.36 (.09–1.50).14
Bloody diarrhea17 (25.4)322 (7.4)4.29 (2.44–7.52)<.001c
Constipation2 (3.0)104 (2.4)1.27 (.31–5.24).74
Headache27 (40.3)1629 (37.2)1.14 (.70–1.86).60
HIV/AIDS1 (1.5)50 (1.1)1.31 (.18–9.64).79
No medication in last 8 wk42 (62.7)2260 (51.6)0.64 (.40–1.05).07
Severe/moderate dehydration3 (4.5)59 (1.3)3.30 (1.01–10.82).049c
Mild dehydration5 (7.5)493 (11.3)0.66 (.26–1.65).37
Coated tongue1 (1.5)8 (0.2)8.28 (1.02–67.15).02c6.11 (.73–51.02).10
Tenderness/rebound tenderness3 (4.5)122 (2.8)1.64 (.51–5.28).41
dCurrent high fever14 (20.9)436 (10.0)2.64 (1.42–4.92).002c2.02 (1.04–3.94).04c
eCurrent low fever15 (22.4)812 (18.5)1.52 (.83–2.78).171.21 (.64–2.28).56

Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; HIV, human immunodeficiency virus; OR, odds ratio;

aData represent no. (%) of participants unless otherwise specified.

baORs for variables retained in the final model (at P < .1), with age and sex of respondents forced into the final model.

cSignificant at P < .05.

dHigh fever defined as temperature ≥38.0°C.

eLow fever defined as temperature <37.2°C.

Table 3.

Clinical Factors Associated With Shigella Diarrhea

Variable/ResponseParticipants, No. (%)aCrude OR (95% CI)P ValueaOR (95% CI)bP Value
Shigella Positive With Diarrhea (n = 67)Shigella Negative With Diarrhea (n = 4380)
Age, median (range), y5 (1–56)6 (0–76).411.00 (.98–1.01).61
Female respondent37 (55.2)2204 (50.3)1.22 (.75–1.98).431.25 (.77–2.03).32
Fever in past 3 d55 (82.1)2926 (66.8)2.28 (1.22–4.27).008c1.85 (.95–3.63).07
Vomiting29 (43.3)2220 (50.7)0.74 (.46–1.21).23
Abdominal pain51 (76.1)3196 (73.0)1.18 (.67–2.08).56
Distension2 (3.0)341 (7.8)0.36 (.09–1.50).14
Bloody diarrhea17 (25.4)322 (7.4)4.29 (2.44–7.52)<.001c
Constipation2 (3.0)104 (2.4)1.27 (.31–5.24).74
Headache27 (40.3)1629 (37.2)1.14 (.70–1.86).60
HIV/AIDS1 (1.5)50 (1.1)1.31 (.18–9.64).79
No medication in last 8 wk42 (62.7)2260 (51.6)0.64 (.40–1.05).07
Severe/moderate dehydration3 (4.5)59 (1.3)3.30 (1.01–10.82).049c
Mild dehydration5 (7.5)493 (11.3)0.66 (.26–1.65).37
Coated tongue1 (1.5)8 (0.2)8.28 (1.02–67.15).02c6.11 (.73–51.02).10
Tenderness/rebound tenderness3 (4.5)122 (2.8)1.64 (.51–5.28).41
dCurrent high fever14 (20.9)436 (10.0)2.64 (1.42–4.92).002c2.02 (1.04–3.94).04c
eCurrent low fever15 (22.4)812 (18.5)1.52 (.83–2.78).171.21 (.64–2.28).56
Variable/ResponseParticipants, No. (%)aCrude OR (95% CI)P ValueaOR (95% CI)bP Value
Shigella Positive With Diarrhea (n = 67)Shigella Negative With Diarrhea (n = 4380)
Age, median (range), y5 (1–56)6 (0–76).411.00 (.98–1.01).61
Female respondent37 (55.2)2204 (50.3)1.22 (.75–1.98).431.25 (.77–2.03).32
Fever in past 3 d55 (82.1)2926 (66.8)2.28 (1.22–4.27).008c1.85 (.95–3.63).07
Vomiting29 (43.3)2220 (50.7)0.74 (.46–1.21).23
Abdominal pain51 (76.1)3196 (73.0)1.18 (.67–2.08).56
Distension2 (3.0)341 (7.8)0.36 (.09–1.50).14
Bloody diarrhea17 (25.4)322 (7.4)4.29 (2.44–7.52)<.001c
Constipation2 (3.0)104 (2.4)1.27 (.31–5.24).74
Headache27 (40.3)1629 (37.2)1.14 (.70–1.86).60
HIV/AIDS1 (1.5)50 (1.1)1.31 (.18–9.64).79
No medication in last 8 wk42 (62.7)2260 (51.6)0.64 (.40–1.05).07
Severe/moderate dehydration3 (4.5)59 (1.3)3.30 (1.01–10.82).049c
Mild dehydration5 (7.5)493 (11.3)0.66 (.26–1.65).37
Coated tongue1 (1.5)8 (0.2)8.28 (1.02–67.15).02c6.11 (.73–51.02).10
Tenderness/rebound tenderness3 (4.5)122 (2.8)1.64 (.51–5.28).41
dCurrent high fever14 (20.9)436 (10.0)2.64 (1.42–4.92).002c2.02 (1.04–3.94).04c
eCurrent low fever15 (22.4)812 (18.5)1.52 (.83–2.78).171.21 (.64–2.28).56

Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; HIV, human immunodeficiency virus; OR, odds ratio;

aData represent no. (%) of participants unless otherwise specified.

baORs for variables retained in the final model (at P < .1), with age and sex of respondents forced into the final model.

cSignificant at P < .05.

dHigh fever defined as temperature ≥38.0°C.

eLow fever defined as temperature <37.2°C.

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