| Topic . | Key points . | References . |
|---|---|---|
| Neurotransmitters | Amino acids from proteins, vitamins, and minerals are essential for synthesizing and regulating neurotransmitters (eg, serotonin, dopamine, norepinephrine). | Briguglio et al, 201865 |
| Nutrient deficiencies can disrupt neurotransmitter balance and contribute to the development or exacerbation of mental health disorders. | ||
| Antioxidants (eg, vitamins C, E, phytonutrients) protect against oxidative stress, crucial for the brain vulnerable to oxidative damage. | Calderón‐Ospina and Nava‐Mesa, 202036; Olubukola Sinbad et al, 201986 | |
| Omega-3 fatty acids (eg, eicosapentaenoic acid and docosahexaenoic acid) possess anti-inflammatory properties, which potentially can alleviatie symptoms of mood disorders. | Dighriri et al, 202263; Grosso et al, 201428; Keller, 200229; Lange, 202039 | |
| Diet influences the gut-brain axis, influencing the gut microbiome, which, in turn, can affect systemic inflammation, mood, and behavior. | Bear et al, 2020100; Clapp et al, 2017101; Kumar et al, 202357 | |
| Inflammation and oxidative stress | Chronic inflammation and oxidative stress contribute to the development and progression of mental disorders. | Ouabbou et al, 2020103; Salim, 2014104 |
| Western diet high in processed foods and unhealthy fats promotes inflammation and oxidative stress, negatively affecting brain function and mental health. | Christ et al, 2019108 | |
| Diets rich in fruits, vegetables, whole grains, and healthy fats (eg, Mediterranean diet) have anti-inflammatory and antioxidant properties that potentially reduce the risk of mental disorders. | Tsigalou et al, 2020109 | |
| Gut microbiota and neuroplasticity | The gut-brain axis, a bidirectional communication system, is influenced by nutritional factors, such as dietary fiber and prebiotics. | Cryan and Dinan, 2012111 |
| Gut microbiota composition and diversity influence brain function, neuroplasticity, and mental health. | Holscher, 2017112 | |
| Imbalances in the gut microbiota, often linked to poor dietary choices, may contribute to the development of mental disorders. | Bear et al, 2020100 | |
| Dietary interventions and probiotics can promote a healthy gut-brain axis and support mental well-being. | Clapp et al, 2017101; Bear et al, 2020100; Kumar et al, 202357 | |
| Overall summary | Nutrition influences mental health through neurotransmitter synthesis, inflammation and oxidative stress modulation, and the gut-brain axis. | |
| Adopting a balanced and nutrient-rich diet is crucial for mental health promotion and treatment. | ||
| Ongoing research is needed to understand the complex interactions between nutrition and mental health and to develop targeted interventions for improved mental well-being. | ||
| Topic . | Key points . | References . |
|---|---|---|
| Neurotransmitters | Amino acids from proteins, vitamins, and minerals are essential for synthesizing and regulating neurotransmitters (eg, serotonin, dopamine, norepinephrine). | Briguglio et al, 201865 |
| Nutrient deficiencies can disrupt neurotransmitter balance and contribute to the development or exacerbation of mental health disorders. | ||
| Antioxidants (eg, vitamins C, E, phytonutrients) protect against oxidative stress, crucial for the brain vulnerable to oxidative damage. | Calderón‐Ospina and Nava‐Mesa, 202036; Olubukola Sinbad et al, 201986 | |
| Omega-3 fatty acids (eg, eicosapentaenoic acid and docosahexaenoic acid) possess anti-inflammatory properties, which potentially can alleviatie symptoms of mood disorders. | Dighriri et al, 202263; Grosso et al, 201428; Keller, 200229; Lange, 202039 | |
| Diet influences the gut-brain axis, influencing the gut microbiome, which, in turn, can affect systemic inflammation, mood, and behavior. | Bear et al, 2020100; Clapp et al, 2017101; Kumar et al, 202357 | |
| Inflammation and oxidative stress | Chronic inflammation and oxidative stress contribute to the development and progression of mental disorders. | Ouabbou et al, 2020103; Salim, 2014104 |
| Western diet high in processed foods and unhealthy fats promotes inflammation and oxidative stress, negatively affecting brain function and mental health. | Christ et al, 2019108 | |
| Diets rich in fruits, vegetables, whole grains, and healthy fats (eg, Mediterranean diet) have anti-inflammatory and antioxidant properties that potentially reduce the risk of mental disorders. | Tsigalou et al, 2020109 | |
| Gut microbiota and neuroplasticity | The gut-brain axis, a bidirectional communication system, is influenced by nutritional factors, such as dietary fiber and prebiotics. | Cryan and Dinan, 2012111 |
| Gut microbiota composition and diversity influence brain function, neuroplasticity, and mental health. | Holscher, 2017112 | |
| Imbalances in the gut microbiota, often linked to poor dietary choices, may contribute to the development of mental disorders. | Bear et al, 2020100 | |
| Dietary interventions and probiotics can promote a healthy gut-brain axis and support mental well-being. | Clapp et al, 2017101; Bear et al, 2020100; Kumar et al, 202357 | |
| Overall summary | Nutrition influences mental health through neurotransmitter synthesis, inflammation and oxidative stress modulation, and the gut-brain axis. | |
| Adopting a balanced and nutrient-rich diet is crucial for mental health promotion and treatment. | ||
| Ongoing research is needed to understand the complex interactions between nutrition and mental health and to develop targeted interventions for improved mental well-being. | ||
| Topic . | Key points . | References . |
|---|---|---|
| Neurotransmitters | Amino acids from proteins, vitamins, and minerals are essential for synthesizing and regulating neurotransmitters (eg, serotonin, dopamine, norepinephrine). | Briguglio et al, 201865 |
| Nutrient deficiencies can disrupt neurotransmitter balance and contribute to the development or exacerbation of mental health disorders. | ||
| Antioxidants (eg, vitamins C, E, phytonutrients) protect against oxidative stress, crucial for the brain vulnerable to oxidative damage. | Calderón‐Ospina and Nava‐Mesa, 202036; Olubukola Sinbad et al, 201986 | |
| Omega-3 fatty acids (eg, eicosapentaenoic acid and docosahexaenoic acid) possess anti-inflammatory properties, which potentially can alleviatie symptoms of mood disorders. | Dighriri et al, 202263; Grosso et al, 201428; Keller, 200229; Lange, 202039 | |
| Diet influences the gut-brain axis, influencing the gut microbiome, which, in turn, can affect systemic inflammation, mood, and behavior. | Bear et al, 2020100; Clapp et al, 2017101; Kumar et al, 202357 | |
| Inflammation and oxidative stress | Chronic inflammation and oxidative stress contribute to the development and progression of mental disorders. | Ouabbou et al, 2020103; Salim, 2014104 |
| Western diet high in processed foods and unhealthy fats promotes inflammation and oxidative stress, negatively affecting brain function and mental health. | Christ et al, 2019108 | |
| Diets rich in fruits, vegetables, whole grains, and healthy fats (eg, Mediterranean diet) have anti-inflammatory and antioxidant properties that potentially reduce the risk of mental disorders. | Tsigalou et al, 2020109 | |
| Gut microbiota and neuroplasticity | The gut-brain axis, a bidirectional communication system, is influenced by nutritional factors, such as dietary fiber and prebiotics. | Cryan and Dinan, 2012111 |
| Gut microbiota composition and diversity influence brain function, neuroplasticity, and mental health. | Holscher, 2017112 | |
| Imbalances in the gut microbiota, often linked to poor dietary choices, may contribute to the development of mental disorders. | Bear et al, 2020100 | |
| Dietary interventions and probiotics can promote a healthy gut-brain axis and support mental well-being. | Clapp et al, 2017101; Bear et al, 2020100; Kumar et al, 202357 | |
| Overall summary | Nutrition influences mental health through neurotransmitter synthesis, inflammation and oxidative stress modulation, and the gut-brain axis. | |
| Adopting a balanced and nutrient-rich diet is crucial for mental health promotion and treatment. | ||
| Ongoing research is needed to understand the complex interactions between nutrition and mental health and to develop targeted interventions for improved mental well-being. | ||
| Topic . | Key points . | References . |
|---|---|---|
| Neurotransmitters | Amino acids from proteins, vitamins, and minerals are essential for synthesizing and regulating neurotransmitters (eg, serotonin, dopamine, norepinephrine). | Briguglio et al, 201865 |
| Nutrient deficiencies can disrupt neurotransmitter balance and contribute to the development or exacerbation of mental health disorders. | ||
| Antioxidants (eg, vitamins C, E, phytonutrients) protect against oxidative stress, crucial for the brain vulnerable to oxidative damage. | Calderón‐Ospina and Nava‐Mesa, 202036; Olubukola Sinbad et al, 201986 | |
| Omega-3 fatty acids (eg, eicosapentaenoic acid and docosahexaenoic acid) possess anti-inflammatory properties, which potentially can alleviatie symptoms of mood disorders. | Dighriri et al, 202263; Grosso et al, 201428; Keller, 200229; Lange, 202039 | |
| Diet influences the gut-brain axis, influencing the gut microbiome, which, in turn, can affect systemic inflammation, mood, and behavior. | Bear et al, 2020100; Clapp et al, 2017101; Kumar et al, 202357 | |
| Inflammation and oxidative stress | Chronic inflammation and oxidative stress contribute to the development and progression of mental disorders. | Ouabbou et al, 2020103; Salim, 2014104 |
| Western diet high in processed foods and unhealthy fats promotes inflammation and oxidative stress, negatively affecting brain function and mental health. | Christ et al, 2019108 | |
| Diets rich in fruits, vegetables, whole grains, and healthy fats (eg, Mediterranean diet) have anti-inflammatory and antioxidant properties that potentially reduce the risk of mental disorders. | Tsigalou et al, 2020109 | |
| Gut microbiota and neuroplasticity | The gut-brain axis, a bidirectional communication system, is influenced by nutritional factors, such as dietary fiber and prebiotics. | Cryan and Dinan, 2012111 |
| Gut microbiota composition and diversity influence brain function, neuroplasticity, and mental health. | Holscher, 2017112 | |
| Imbalances in the gut microbiota, often linked to poor dietary choices, may contribute to the development of mental disorders. | Bear et al, 2020100 | |
| Dietary interventions and probiotics can promote a healthy gut-brain axis and support mental well-being. | Clapp et al, 2017101; Bear et al, 2020100; Kumar et al, 202357 | |
| Overall summary | Nutrition influences mental health through neurotransmitter synthesis, inflammation and oxidative stress modulation, and the gut-brain axis. | |
| Adopting a balanced and nutrient-rich diet is crucial for mental health promotion and treatment. | ||
| Ongoing research is needed to understand the complex interactions between nutrition and mental health and to develop targeted interventions for improved mental well-being. | ||
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