Aneurysm characteristics at presentation for all ascending aortic aneurysm patients (n = 1858) and stratified by sex (male, female) and age groups (non-elderly, elderly)
| . | Overall (n = 1858) . | Men (n = 1270) . | Women (n = 588) . | P-value (men/women) . | Non-elderly (n = 1401) . | Elderly (n = 457) . | P-value (non-elderly/elderly) . |
|---|---|---|---|---|---|---|---|
| Age at diagnosis (years) | 60.9 (50.5, 69.3) | 59.0 (49.3, 68.0) | 65.4 (53.4, 71.7) | <.001 | 55.9 (45.6, 63.2) | 74.2 (71.6, 77.5) | <.001 |
| First presentation (n) | .541 | <.001 | |||||
| Coincidental finding (n) | 833 (44.8) | 571 (45.0) | 262 (44.6) | 578 (41.3) | 255 (55.8) | <.001 | |
| Family screening (n) | 237 (12.8) | 170 (13.4) | 67 (11.4) | 221 (15.8) | 16 (3.5) | <.001 | |
| Suspected connective tissue disease (n) | 39 (2.1) | 24 (1.9) | 15 (2.6) | 39 (2.8) | 0 (0.0) | .001 | |
| Exercise related symptoms/complaints (n) | 186 (10.0) | 121 (9.5) | 65 (11.1) | 140 (10.0) | 46 (10.1) | 1.000 | |
| Non-exercise related symptoms/complaints (n) | 237 (12.8) | 164 (12.9) | 73 (12.4) | 176 (12.6) | 61 (13.3) | .740 | |
| Maximum aortic diameter (mm) | 46.0 (42.0, 51.0) | 46.5 (43.0, 51.0) | 45.0 (42.0, 53.0) | .388 | 46.0 (42.0, 50.0) | 48.0 (43.0, 54.0) | <.001 |
| ASI (mm/m2) | 22.6 (20.1, 26.1) | 21.7 (19.4, 24.3) | 25.4 (22.5, 29.2) | <.001 | 22.1 (19.7, 25.1) | 24.9 (21.9, 28.9) | <.001 |
| AHI (mm/m) | 26.1 (23.9, 29.4) | 25.6 (23.6, 28.4) | 27.4 (25.0, 31.8) | <.001 | 25.7 (23.7, 28.6) | 27.8 (25.0, 31.4) | <.001 |
| Max aortic diameter at aortic sinuses (n) | 516 (27.8) | 407 (32.0) | 109 (18.5) | <.001 | 443 (34.2) | 73 (17.7) | <.001 |
| Max aortic diameter at tubular ascending (n) | 1127 (66.0) | 790 (62.2) | 437 (74.3) | <.001 | 880 (67.8) | 347 (84.2) | <.001 |
| Annular diameter (mm) | 26.0 (24.0, 29.2) | 27.0 (25.0, 30.0) | 24.2 (22.3, 25.5) | <.001 | 26.0 (23.78, 29.13) | 48.0 (43.0, 54.0) | .959 |
| Aortic sinus diameter (mm) | 42.0 (39.0, 46.0) | 43.0 (40.0, 47.0) | 40.0 (35.0, 42.3) | <.001 | 42.0 (39.55, 46.55) | 41.0 (38.0, 44.3) | .008 |
| Tubular ascending aortic diameter (mm) | 45.0 (41.0, 51.0) | 45.0 (41.0, 50.0) | 45.0 (41.0, 52.0) | .132 | 45.0 (40.0, 50.0) | 48.0 (42.0, 54.0) | <.001 |
| Arch diameter (mm) | 32.0 (27.0, 38.3) | 32.0 (28.0, 38.0) | 32.0 (25.0, 39.0) | .057 | 30.0 (26.0, 35.0) | 36.0 (32.0, 41.5) | <.001 |
| Descending diameter (mm) | 32.0 (27.0, 43.0) | 31.0 (27.0, 41.0) | 33.0 (25.5, 46.0) | .666 | 29.0 (25.0, 38.0) | 41.0 (31.0, 52.8) | <.001 |
| Involvement annulus (n) | 50 (2.7) | 46 (3.6) | 4 (0.7) | <.001 | 43 (3.1) | 7 (1.5) | .879 |
| Involvement aortic sinuses (n) | 671 (36.1) | 544 (42.8) | 127 (21.6) | <.001 | 555 (39.6) | 116 (25.4) | .023 |
| Involvement tubular ascending (n) | 1335 (71.9) | 891 (70.2) | 444 (75.5) | .030 | 962 (68.7) | 373 (81.6) | <.001 |
| Involvement arch (n) | 74 (4.0) | 48 (3.8) | 26 (4.4) | .915 | 34 (2.4) | 40 (9.2) | <.001 |
| Involvement descending (n) | 130 (7.0) | 72 (5.7) | 58 (9.9) | .172 | 51 (3.6) | 79 (17.3) | <.001 |
| . | Overall (n = 1858) . | Men (n = 1270) . | Women (n = 588) . | P-value (men/women) . | Non-elderly (n = 1401) . | Elderly (n = 457) . | P-value (non-elderly/elderly) . |
|---|---|---|---|---|---|---|---|
| Age at diagnosis (years) | 60.9 (50.5, 69.3) | 59.0 (49.3, 68.0) | 65.4 (53.4, 71.7) | <.001 | 55.9 (45.6, 63.2) | 74.2 (71.6, 77.5) | <.001 |
| First presentation (n) | .541 | <.001 | |||||
| Coincidental finding (n) | 833 (44.8) | 571 (45.0) | 262 (44.6) | 578 (41.3) | 255 (55.8) | <.001 | |
| Family screening (n) | 237 (12.8) | 170 (13.4) | 67 (11.4) | 221 (15.8) | 16 (3.5) | <.001 | |
| Suspected connective tissue disease (n) | 39 (2.1) | 24 (1.9) | 15 (2.6) | 39 (2.8) | 0 (0.0) | .001 | |
| Exercise related symptoms/complaints (n) | 186 (10.0) | 121 (9.5) | 65 (11.1) | 140 (10.0) | 46 (10.1) | 1.000 | |
| Non-exercise related symptoms/complaints (n) | 237 (12.8) | 164 (12.9) | 73 (12.4) | 176 (12.6) | 61 (13.3) | .740 | |
| Maximum aortic diameter (mm) | 46.0 (42.0, 51.0) | 46.5 (43.0, 51.0) | 45.0 (42.0, 53.0) | .388 | 46.0 (42.0, 50.0) | 48.0 (43.0, 54.0) | <.001 |
| ASI (mm/m2) | 22.6 (20.1, 26.1) | 21.7 (19.4, 24.3) | 25.4 (22.5, 29.2) | <.001 | 22.1 (19.7, 25.1) | 24.9 (21.9, 28.9) | <.001 |
| AHI (mm/m) | 26.1 (23.9, 29.4) | 25.6 (23.6, 28.4) | 27.4 (25.0, 31.8) | <.001 | 25.7 (23.7, 28.6) | 27.8 (25.0, 31.4) | <.001 |
| Max aortic diameter at aortic sinuses (n) | 516 (27.8) | 407 (32.0) | 109 (18.5) | <.001 | 443 (34.2) | 73 (17.7) | <.001 |
| Max aortic diameter at tubular ascending (n) | 1127 (66.0) | 790 (62.2) | 437 (74.3) | <.001 | 880 (67.8) | 347 (84.2) | <.001 |
| Annular diameter (mm) | 26.0 (24.0, 29.2) | 27.0 (25.0, 30.0) | 24.2 (22.3, 25.5) | <.001 | 26.0 (23.78, 29.13) | 48.0 (43.0, 54.0) | .959 |
| Aortic sinus diameter (mm) | 42.0 (39.0, 46.0) | 43.0 (40.0, 47.0) | 40.0 (35.0, 42.3) | <.001 | 42.0 (39.55, 46.55) | 41.0 (38.0, 44.3) | .008 |
| Tubular ascending aortic diameter (mm) | 45.0 (41.0, 51.0) | 45.0 (41.0, 50.0) | 45.0 (41.0, 52.0) | .132 | 45.0 (40.0, 50.0) | 48.0 (42.0, 54.0) | <.001 |
| Arch diameter (mm) | 32.0 (27.0, 38.3) | 32.0 (28.0, 38.0) | 32.0 (25.0, 39.0) | .057 | 30.0 (26.0, 35.0) | 36.0 (32.0, 41.5) | <.001 |
| Descending diameter (mm) | 32.0 (27.0, 43.0) | 31.0 (27.0, 41.0) | 33.0 (25.5, 46.0) | .666 | 29.0 (25.0, 38.0) | 41.0 (31.0, 52.8) | <.001 |
| Involvement annulus (n) | 50 (2.7) | 46 (3.6) | 4 (0.7) | <.001 | 43 (3.1) | 7 (1.5) | .879 |
| Involvement aortic sinuses (n) | 671 (36.1) | 544 (42.8) | 127 (21.6) | <.001 | 555 (39.6) | 116 (25.4) | .023 |
| Involvement tubular ascending (n) | 1335 (71.9) | 891 (70.2) | 444 (75.5) | .030 | 962 (68.7) | 373 (81.6) | <.001 |
| Involvement arch (n) | 74 (4.0) | 48 (3.8) | 26 (4.4) | .915 | 34 (2.4) | 40 (9.2) | <.001 |
| Involvement descending (n) | 130 (7.0) | 72 (5.7) | 58 (9.9) | .172 | 51 (3.6) | 79 (17.3) | <.001 |
Bold P-values indicate significance at .05 level (P < .05). Non-elderly, <70 years; elderly, ≥70 years.
AHI, aortic height index; ASI, aortic size index.
Aneurysm characteristics at presentation for all ascending aortic aneurysm patients (n = 1858) and stratified by sex (male, female) and age groups (non-elderly, elderly)
| . | Overall (n = 1858) . | Men (n = 1270) . | Women (n = 588) . | P-value (men/women) . | Non-elderly (n = 1401) . | Elderly (n = 457) . | P-value (non-elderly/elderly) . |
|---|---|---|---|---|---|---|---|
| Age at diagnosis (years) | 60.9 (50.5, 69.3) | 59.0 (49.3, 68.0) | 65.4 (53.4, 71.7) | <.001 | 55.9 (45.6, 63.2) | 74.2 (71.6, 77.5) | <.001 |
| First presentation (n) | .541 | <.001 | |||||
| Coincidental finding (n) | 833 (44.8) | 571 (45.0) | 262 (44.6) | 578 (41.3) | 255 (55.8) | <.001 | |
| Family screening (n) | 237 (12.8) | 170 (13.4) | 67 (11.4) | 221 (15.8) | 16 (3.5) | <.001 | |
| Suspected connective tissue disease (n) | 39 (2.1) | 24 (1.9) | 15 (2.6) | 39 (2.8) | 0 (0.0) | .001 | |
| Exercise related symptoms/complaints (n) | 186 (10.0) | 121 (9.5) | 65 (11.1) | 140 (10.0) | 46 (10.1) | 1.000 | |
| Non-exercise related symptoms/complaints (n) | 237 (12.8) | 164 (12.9) | 73 (12.4) | 176 (12.6) | 61 (13.3) | .740 | |
| Maximum aortic diameter (mm) | 46.0 (42.0, 51.0) | 46.5 (43.0, 51.0) | 45.0 (42.0, 53.0) | .388 | 46.0 (42.0, 50.0) | 48.0 (43.0, 54.0) | <.001 |
| ASI (mm/m2) | 22.6 (20.1, 26.1) | 21.7 (19.4, 24.3) | 25.4 (22.5, 29.2) | <.001 | 22.1 (19.7, 25.1) | 24.9 (21.9, 28.9) | <.001 |
| AHI (mm/m) | 26.1 (23.9, 29.4) | 25.6 (23.6, 28.4) | 27.4 (25.0, 31.8) | <.001 | 25.7 (23.7, 28.6) | 27.8 (25.0, 31.4) | <.001 |
| Max aortic diameter at aortic sinuses (n) | 516 (27.8) | 407 (32.0) | 109 (18.5) | <.001 | 443 (34.2) | 73 (17.7) | <.001 |
| Max aortic diameter at tubular ascending (n) | 1127 (66.0) | 790 (62.2) | 437 (74.3) | <.001 | 880 (67.8) | 347 (84.2) | <.001 |
| Annular diameter (mm) | 26.0 (24.0, 29.2) | 27.0 (25.0, 30.0) | 24.2 (22.3, 25.5) | <.001 | 26.0 (23.78, 29.13) | 48.0 (43.0, 54.0) | .959 |
| Aortic sinus diameter (mm) | 42.0 (39.0, 46.0) | 43.0 (40.0, 47.0) | 40.0 (35.0, 42.3) | <.001 | 42.0 (39.55, 46.55) | 41.0 (38.0, 44.3) | .008 |
| Tubular ascending aortic diameter (mm) | 45.0 (41.0, 51.0) | 45.0 (41.0, 50.0) | 45.0 (41.0, 52.0) | .132 | 45.0 (40.0, 50.0) | 48.0 (42.0, 54.0) | <.001 |
| Arch diameter (mm) | 32.0 (27.0, 38.3) | 32.0 (28.0, 38.0) | 32.0 (25.0, 39.0) | .057 | 30.0 (26.0, 35.0) | 36.0 (32.0, 41.5) | <.001 |
| Descending diameter (mm) | 32.0 (27.0, 43.0) | 31.0 (27.0, 41.0) | 33.0 (25.5, 46.0) | .666 | 29.0 (25.0, 38.0) | 41.0 (31.0, 52.8) | <.001 |
| Involvement annulus (n) | 50 (2.7) | 46 (3.6) | 4 (0.7) | <.001 | 43 (3.1) | 7 (1.5) | .879 |
| Involvement aortic sinuses (n) | 671 (36.1) | 544 (42.8) | 127 (21.6) | <.001 | 555 (39.6) | 116 (25.4) | .023 |
| Involvement tubular ascending (n) | 1335 (71.9) | 891 (70.2) | 444 (75.5) | .030 | 962 (68.7) | 373 (81.6) | <.001 |
| Involvement arch (n) | 74 (4.0) | 48 (3.8) | 26 (4.4) | .915 | 34 (2.4) | 40 (9.2) | <.001 |
| Involvement descending (n) | 130 (7.0) | 72 (5.7) | 58 (9.9) | .172 | 51 (3.6) | 79 (17.3) | <.001 |
| . | Overall (n = 1858) . | Men (n = 1270) . | Women (n = 588) . | P-value (men/women) . | Non-elderly (n = 1401) . | Elderly (n = 457) . | P-value (non-elderly/elderly) . |
|---|---|---|---|---|---|---|---|
| Age at diagnosis (years) | 60.9 (50.5, 69.3) | 59.0 (49.3, 68.0) | 65.4 (53.4, 71.7) | <.001 | 55.9 (45.6, 63.2) | 74.2 (71.6, 77.5) | <.001 |
| First presentation (n) | .541 | <.001 | |||||
| Coincidental finding (n) | 833 (44.8) | 571 (45.0) | 262 (44.6) | 578 (41.3) | 255 (55.8) | <.001 | |
| Family screening (n) | 237 (12.8) | 170 (13.4) | 67 (11.4) | 221 (15.8) | 16 (3.5) | <.001 | |
| Suspected connective tissue disease (n) | 39 (2.1) | 24 (1.9) | 15 (2.6) | 39 (2.8) | 0 (0.0) | .001 | |
| Exercise related symptoms/complaints (n) | 186 (10.0) | 121 (9.5) | 65 (11.1) | 140 (10.0) | 46 (10.1) | 1.000 | |
| Non-exercise related symptoms/complaints (n) | 237 (12.8) | 164 (12.9) | 73 (12.4) | 176 (12.6) | 61 (13.3) | .740 | |
| Maximum aortic diameter (mm) | 46.0 (42.0, 51.0) | 46.5 (43.0, 51.0) | 45.0 (42.0, 53.0) | .388 | 46.0 (42.0, 50.0) | 48.0 (43.0, 54.0) | <.001 |
| ASI (mm/m2) | 22.6 (20.1, 26.1) | 21.7 (19.4, 24.3) | 25.4 (22.5, 29.2) | <.001 | 22.1 (19.7, 25.1) | 24.9 (21.9, 28.9) | <.001 |
| AHI (mm/m) | 26.1 (23.9, 29.4) | 25.6 (23.6, 28.4) | 27.4 (25.0, 31.8) | <.001 | 25.7 (23.7, 28.6) | 27.8 (25.0, 31.4) | <.001 |
| Max aortic diameter at aortic sinuses (n) | 516 (27.8) | 407 (32.0) | 109 (18.5) | <.001 | 443 (34.2) | 73 (17.7) | <.001 |
| Max aortic diameter at tubular ascending (n) | 1127 (66.0) | 790 (62.2) | 437 (74.3) | <.001 | 880 (67.8) | 347 (84.2) | <.001 |
| Annular diameter (mm) | 26.0 (24.0, 29.2) | 27.0 (25.0, 30.0) | 24.2 (22.3, 25.5) | <.001 | 26.0 (23.78, 29.13) | 48.0 (43.0, 54.0) | .959 |
| Aortic sinus diameter (mm) | 42.0 (39.0, 46.0) | 43.0 (40.0, 47.0) | 40.0 (35.0, 42.3) | <.001 | 42.0 (39.55, 46.55) | 41.0 (38.0, 44.3) | .008 |
| Tubular ascending aortic diameter (mm) | 45.0 (41.0, 51.0) | 45.0 (41.0, 50.0) | 45.0 (41.0, 52.0) | .132 | 45.0 (40.0, 50.0) | 48.0 (42.0, 54.0) | <.001 |
| Arch diameter (mm) | 32.0 (27.0, 38.3) | 32.0 (28.0, 38.0) | 32.0 (25.0, 39.0) | .057 | 30.0 (26.0, 35.0) | 36.0 (32.0, 41.5) | <.001 |
| Descending diameter (mm) | 32.0 (27.0, 43.0) | 31.0 (27.0, 41.0) | 33.0 (25.5, 46.0) | .666 | 29.0 (25.0, 38.0) | 41.0 (31.0, 52.8) | <.001 |
| Involvement annulus (n) | 50 (2.7) | 46 (3.6) | 4 (0.7) | <.001 | 43 (3.1) | 7 (1.5) | .879 |
| Involvement aortic sinuses (n) | 671 (36.1) | 544 (42.8) | 127 (21.6) | <.001 | 555 (39.6) | 116 (25.4) | .023 |
| Involvement tubular ascending (n) | 1335 (71.9) | 891 (70.2) | 444 (75.5) | .030 | 962 (68.7) | 373 (81.6) | <.001 |
| Involvement arch (n) | 74 (4.0) | 48 (3.8) | 26 (4.4) | .915 | 34 (2.4) | 40 (9.2) | <.001 |
| Involvement descending (n) | 130 (7.0) | 72 (5.7) | 58 (9.9) | .172 | 51 (3.6) | 79 (17.3) | <.001 |
Bold P-values indicate significance at .05 level (P < .05). Non-elderly, <70 years; elderly, ≥70 years.
AHI, aortic height index; ASI, aortic size index.
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