Table 2

ChatGPT-4o performance in predicting the final diagnosis of febrile returning travellers presented to the emergency department at Sheba Medical Centre during 2009–2024 (N = 114)

 ChatGPT-4o correct hits
 N% (95% CI)
Primary outcome:
Success rate in predicting the final diagnosis when requested to specify the top three differentials
All cases (N = 114)8978.1 (69.4, 85.3)
Only malaria cases (N = 48)4797.9 (88.9, 100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
Secondary outcomes:
Success rate in predicting the final diagnosis when requested to specify the single most likely diagnosis
All cases (N = 114)7868.4 (59.1, 76.8)
Only malaria cases (N = 48)4389.6 (77.3, 96.5)
Only dengue cases (N = 19)1684.2 (60.4, 96.6)
Success rate in recommending a diagnostic test that could confirm the final diagnosis
All cases (N = 114)9482.5 (74.2, 88.9)
Only malaria cases (N = 48)48100 (93–100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
 ChatGPT-4o correct hits
 N% (95% CI)
Primary outcome:
Success rate in predicting the final diagnosis when requested to specify the top three differentials
All cases (N = 114)8978.1 (69.4, 85.3)
Only malaria cases (N = 48)4797.9 (88.9, 100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
Secondary outcomes:
Success rate in predicting the final diagnosis when requested to specify the single most likely diagnosis
All cases (N = 114)7868.4 (59.1, 76.8)
Only malaria cases (N = 48)4389.6 (77.3, 96.5)
Only dengue cases (N = 19)1684.2 (60.4, 96.6)
Success rate in recommending a diagnostic test that could confirm the final diagnosis
All cases (N = 114)9482.5 (74.2, 88.9)
Only malaria cases (N = 48)48100 (93–100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
Table 2

ChatGPT-4o performance in predicting the final diagnosis of febrile returning travellers presented to the emergency department at Sheba Medical Centre during 2009–2024 (N = 114)

 ChatGPT-4o correct hits
 N% (95% CI)
Primary outcome:
Success rate in predicting the final diagnosis when requested to specify the top three differentials
All cases (N = 114)8978.1 (69.4, 85.3)
Only malaria cases (N = 48)4797.9 (88.9, 100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
Secondary outcomes:
Success rate in predicting the final diagnosis when requested to specify the single most likely diagnosis
All cases (N = 114)7868.4 (59.1, 76.8)
Only malaria cases (N = 48)4389.6 (77.3, 96.5)
Only dengue cases (N = 19)1684.2 (60.4, 96.6)
Success rate in recommending a diagnostic test that could confirm the final diagnosis
All cases (N = 114)9482.5 (74.2, 88.9)
Only malaria cases (N = 48)48100 (93–100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
 ChatGPT-4o correct hits
 N% (95% CI)
Primary outcome:
Success rate in predicting the final diagnosis when requested to specify the top three differentials
All cases (N = 114)8978.1 (69.4, 85.3)
Only malaria cases (N = 48)4797.9 (88.9, 100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
Secondary outcomes:
Success rate in predicting the final diagnosis when requested to specify the single most likely diagnosis
All cases (N = 114)7868.4 (59.1, 76.8)
Only malaria cases (N = 48)4389.6 (77.3, 96.5)
Only dengue cases (N = 19)1684.2 (60.4, 96.6)
Success rate in recommending a diagnostic test that could confirm the final diagnosis
All cases (N = 114)9482.5 (74.2, 88.9)
Only malaria cases (N = 48)48100 (93–100)
Only dengue cases (N = 19)1894.7 (74.0, 99.9)
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