Different measures of in-hospital medication changes: directions of change and differences in medications at discharge compared to admission
| Directions of medication change | |
| Medications increased | Number of new medications started and number of medications with dose increases at discharge compared to admission (considering all drug classes) |
| Medications decreased | Number of medications ceased and number of medications with dose decreases at discharge compared to admission (considering all drug classes) |
| PIMsa increased | Number of new PIMs started and number of PIMs with dose increases at discharge compared to admission (PIMs were identified using Beers Criteria 2015) |
| PIMs decreased | Number of PIMs ceased and number of PIMs with dose decreases at discharge compared to admission |
| DBIb-contributing medications increased | Number of new DBI-contributing medications started and number of DBI-contributing medications with dose increases at discharge compared to admission (DBI is a measure of the cumulative exposure to anticholinergic and sedative medications) |
| DBI-contributing medications decreased | Number of DBI-contributing medications ceased and number of DBI-contributing medications with dose decreases at discharge compared to admission |
| Difference in medications at discharge compared to admission | |
| Difference in number of medications | Difference in overall number of medications at discharge compared to admission (considering all drug classes) |
| Difference in number of PIMs | Difference in number of PIMs at discharge compared to admission (based on Beers Criteria 2015) |
| Difference in DBI score | Difference in the DBI score at discharge compared to admission |
| Directions of medication change | |
| Medications increased | Number of new medications started and number of medications with dose increases at discharge compared to admission (considering all drug classes) |
| Medications decreased | Number of medications ceased and number of medications with dose decreases at discharge compared to admission (considering all drug classes) |
| PIMsa increased | Number of new PIMs started and number of PIMs with dose increases at discharge compared to admission (PIMs were identified using Beers Criteria 2015) |
| PIMs decreased | Number of PIMs ceased and number of PIMs with dose decreases at discharge compared to admission |
| DBIb-contributing medications increased | Number of new DBI-contributing medications started and number of DBI-contributing medications with dose increases at discharge compared to admission (DBI is a measure of the cumulative exposure to anticholinergic and sedative medications) |
| DBI-contributing medications decreased | Number of DBI-contributing medications ceased and number of DBI-contributing medications with dose decreases at discharge compared to admission |
| Difference in medications at discharge compared to admission | |
| Difference in number of medications | Difference in overall number of medications at discharge compared to admission (considering all drug classes) |
| Difference in number of PIMs | Difference in number of PIMs at discharge compared to admission (based on Beers Criteria 2015) |
| Difference in DBI score | Difference in the DBI score at discharge compared to admission |
aPIMs, potentially inappropriate medications as per Beers Criteria 2015.
bDBI, Drug Burden Index.
Different measures of in-hospital medication changes: directions of change and differences in medications at discharge compared to admission
| Directions of medication change | |
| Medications increased | Number of new medications started and number of medications with dose increases at discharge compared to admission (considering all drug classes) |
| Medications decreased | Number of medications ceased and number of medications with dose decreases at discharge compared to admission (considering all drug classes) |
| PIMsa increased | Number of new PIMs started and number of PIMs with dose increases at discharge compared to admission (PIMs were identified using Beers Criteria 2015) |
| PIMs decreased | Number of PIMs ceased and number of PIMs with dose decreases at discharge compared to admission |
| DBIb-contributing medications increased | Number of new DBI-contributing medications started and number of DBI-contributing medications with dose increases at discharge compared to admission (DBI is a measure of the cumulative exposure to anticholinergic and sedative medications) |
| DBI-contributing medications decreased | Number of DBI-contributing medications ceased and number of DBI-contributing medications with dose decreases at discharge compared to admission |
| Difference in medications at discharge compared to admission | |
| Difference in number of medications | Difference in overall number of medications at discharge compared to admission (considering all drug classes) |
| Difference in number of PIMs | Difference in number of PIMs at discharge compared to admission (based on Beers Criteria 2015) |
| Difference in DBI score | Difference in the DBI score at discharge compared to admission |
| Directions of medication change | |
| Medications increased | Number of new medications started and number of medications with dose increases at discharge compared to admission (considering all drug classes) |
| Medications decreased | Number of medications ceased and number of medications with dose decreases at discharge compared to admission (considering all drug classes) |
| PIMsa increased | Number of new PIMs started and number of PIMs with dose increases at discharge compared to admission (PIMs were identified using Beers Criteria 2015) |
| PIMs decreased | Number of PIMs ceased and number of PIMs with dose decreases at discharge compared to admission |
| DBIb-contributing medications increased | Number of new DBI-contributing medications started and number of DBI-contributing medications with dose increases at discharge compared to admission (DBI is a measure of the cumulative exposure to anticholinergic and sedative medications) |
| DBI-contributing medications decreased | Number of DBI-contributing medications ceased and number of DBI-contributing medications with dose decreases at discharge compared to admission |
| Difference in medications at discharge compared to admission | |
| Difference in number of medications | Difference in overall number of medications at discharge compared to admission (considering all drug classes) |
| Difference in number of PIMs | Difference in number of PIMs at discharge compared to admission (based on Beers Criteria 2015) |
| Difference in DBI score | Difference in the DBI score at discharge compared to admission |
aPIMs, potentially inappropriate medications as per Beers Criteria 2015.
bDBI, Drug Burden Index.
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