Table 4.

Ratios of estrogens and androgens in AT in users and nonusers of HT

 Subcutaneous adipose tissueVisceral adipose tissueP-valueHT−/+a
RatioHT−HT+HT−HT+Sc ATVisc AT
E2/E10.07 (0.01-0.09)b0.06 (0.05-0.08)c0.04 (0.02-0.07)d0.04 (0.03-0.05)e.57
.48
E2/T0.11 (0.02-0.18)b0.99 (0.30-1.85)f0.08 (0.01-0.13)f0.48 (0.30-1.45)g<.001<.001
E1/A40.06 (0.06-0.08)b0.67 (0.24-1.00)h0.06 (0.04-0.08)f0.26 (0.14-0.57)i<.001<.001
E1 + E2/A4 + T0.06 (0.06-0.11)b0.70 (0.26-1.03)j0.06 (0.04-0.08)f0.27 (0.13-0.69)g<.001<.001
 Subcutaneous adipose tissueVisceral adipose tissueP-valueHT−/+a
RatioHT−HT+HT−HT+Sc ATVisc AT
E2/E10.07 (0.01-0.09)b0.06 (0.05-0.08)c0.04 (0.02-0.07)d0.04 (0.03-0.05)e.57
.48
E2/T0.11 (0.02-0.18)b0.99 (0.30-1.85)f0.08 (0.01-0.13)f0.48 (0.30-1.45)g<.001<.001
E1/A40.06 (0.06-0.08)b0.67 (0.24-1.00)h0.06 (0.04-0.08)f0.26 (0.14-0.57)i<.001<.001
E1 + E2/A4 + T0.06 (0.06-0.11)b0.70 (0.26-1.03)j0.06 (0.04-0.08)f0.27 (0.13-0.69)g<.001<.001

Data are presented as median (interquartile range). Boldface indicates statistical significance.

Abbreviations: A4, androstenedione; E1, estrone; E2, estradiol; HT, hormone therapy; HT−, nonusers of HT; HT+, users of HT; Sc AT, subcutaneous adipose tissue; T, testosterone; Visc AT, visceral adipose tissue.

aIndependent-samples Mann-Whitney U test.

bn = 11.

cn = 21.

dn = 13.

en = 38.

fn = 10.

gn = 22.

hn = 9.

in = 24.

jn = 8.

Table 4.

Ratios of estrogens and androgens in AT in users and nonusers of HT

 Subcutaneous adipose tissueVisceral adipose tissueP-valueHT−/+a
RatioHT−HT+HT−HT+Sc ATVisc AT
E2/E10.07 (0.01-0.09)b0.06 (0.05-0.08)c0.04 (0.02-0.07)d0.04 (0.03-0.05)e.57
.48
E2/T0.11 (0.02-0.18)b0.99 (0.30-1.85)f0.08 (0.01-0.13)f0.48 (0.30-1.45)g<.001<.001
E1/A40.06 (0.06-0.08)b0.67 (0.24-1.00)h0.06 (0.04-0.08)f0.26 (0.14-0.57)i<.001<.001
E1 + E2/A4 + T0.06 (0.06-0.11)b0.70 (0.26-1.03)j0.06 (0.04-0.08)f0.27 (0.13-0.69)g<.001<.001
 Subcutaneous adipose tissueVisceral adipose tissueP-valueHT−/+a
RatioHT−HT+HT−HT+Sc ATVisc AT
E2/E10.07 (0.01-0.09)b0.06 (0.05-0.08)c0.04 (0.02-0.07)d0.04 (0.03-0.05)e.57
.48
E2/T0.11 (0.02-0.18)b0.99 (0.30-1.85)f0.08 (0.01-0.13)f0.48 (0.30-1.45)g<.001<.001
E1/A40.06 (0.06-0.08)b0.67 (0.24-1.00)h0.06 (0.04-0.08)f0.26 (0.14-0.57)i<.001<.001
E1 + E2/A4 + T0.06 (0.06-0.11)b0.70 (0.26-1.03)j0.06 (0.04-0.08)f0.27 (0.13-0.69)g<.001<.001

Data are presented as median (interquartile range). Boldface indicates statistical significance.

Abbreviations: A4, androstenedione; E1, estrone; E2, estradiol; HT, hormone therapy; HT−, nonusers of HT; HT+, users of HT; Sc AT, subcutaneous adipose tissue; T, testosterone; Visc AT, visceral adipose tissue.

aIndependent-samples Mann-Whitney U test.

bn = 11.

cn = 21.

dn = 13.

en = 38.

fn = 10.

gn = 22.

hn = 9.

in = 24.

jn = 8.

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