. | Subcutaneous adipose tissue . | Visceral adipose tissue . | P-valueHT−/+a . | ||
---|---|---|---|---|---|
Ratio . | HT− . | HT+ . | HT− . | HT+ . | Sc ATVisc AT . |
E2/E1 | 0.07 (0.01-0.09)b | 0.06 (0.05-0.08)c | 0.04 (0.02-0.07)d | 0.04 (0.03-0.05)e | .57 .48 |
E2/T | 0.11 (0.02-0.18)b | 0.99 (0.30-1.85)f | 0.08 (0.01-0.13)f | 0.48 (0.30-1.45)g | <.001<.001 |
E1/A4 | 0.06 (0.06-0.08)b | 0.67 (0.24-1.00)h | 0.06 (0.04-0.08)f | 0.26 (0.14-0.57)i | <.001<.001 |
E1 + E2/A4 + T | 0.06 (0.06-0.11)b | 0.70 (0.26-1.03)j | 0.06 (0.04-0.08)f | 0.27 (0.13-0.69)g | <.001<.001 |
. | Subcutaneous adipose tissue . | Visceral adipose tissue . | P-valueHT−/+a . | ||
---|---|---|---|---|---|
Ratio . | HT− . | HT+ . | HT− . | HT+ . | Sc ATVisc AT . |
E2/E1 | 0.07 (0.01-0.09)b | 0.06 (0.05-0.08)c | 0.04 (0.02-0.07)d | 0.04 (0.03-0.05)e | .57 .48 |
E2/T | 0.11 (0.02-0.18)b | 0.99 (0.30-1.85)f | 0.08 (0.01-0.13)f | 0.48 (0.30-1.45)g | <.001<.001 |
E1/A4 | 0.06 (0.06-0.08)b | 0.67 (0.24-1.00)h | 0.06 (0.04-0.08)f | 0.26 (0.14-0.57)i | <.001<.001 |
E1 + E2/A4 + T | 0.06 (0.06-0.11)b | 0.70 (0.26-1.03)j | 0.06 (0.04-0.08)f | 0.27 (0.13-0.69)g | <.001<.001 |
Data are presented as median (interquartile range). Boldface indicates statistical significance.
Abbreviations: A4, androstenedione; E1, estrone; E2, estradiol; HT, hormone therapy; HT−, nonusers of HT; HT+, users of HT; Sc AT, subcutaneous adipose tissue; T, testosterone; Visc AT, visceral adipose tissue.
aIndependent-samples Mann-Whitney U test.
bn = 11.
cn = 21.
dn = 13.
en = 38.
fn = 10.
gn = 22.
hn = 9.
in = 24.
jn = 8.
. | Subcutaneous adipose tissue . | Visceral adipose tissue . | P-valueHT−/+a . | ||
---|---|---|---|---|---|
Ratio . | HT− . | HT+ . | HT− . | HT+ . | Sc ATVisc AT . |
E2/E1 | 0.07 (0.01-0.09)b | 0.06 (0.05-0.08)c | 0.04 (0.02-0.07)d | 0.04 (0.03-0.05)e | .57 .48 |
E2/T | 0.11 (0.02-0.18)b | 0.99 (0.30-1.85)f | 0.08 (0.01-0.13)f | 0.48 (0.30-1.45)g | <.001<.001 |
E1/A4 | 0.06 (0.06-0.08)b | 0.67 (0.24-1.00)h | 0.06 (0.04-0.08)f | 0.26 (0.14-0.57)i | <.001<.001 |
E1 + E2/A4 + T | 0.06 (0.06-0.11)b | 0.70 (0.26-1.03)j | 0.06 (0.04-0.08)f | 0.27 (0.13-0.69)g | <.001<.001 |
. | Subcutaneous adipose tissue . | Visceral adipose tissue . | P-valueHT−/+a . | ||
---|---|---|---|---|---|
Ratio . | HT− . | HT+ . | HT− . | HT+ . | Sc ATVisc AT . |
E2/E1 | 0.07 (0.01-0.09)b | 0.06 (0.05-0.08)c | 0.04 (0.02-0.07)d | 0.04 (0.03-0.05)e | .57 .48 |
E2/T | 0.11 (0.02-0.18)b | 0.99 (0.30-1.85)f | 0.08 (0.01-0.13)f | 0.48 (0.30-1.45)g | <.001<.001 |
E1/A4 | 0.06 (0.06-0.08)b | 0.67 (0.24-1.00)h | 0.06 (0.04-0.08)f | 0.26 (0.14-0.57)i | <.001<.001 |
E1 + E2/A4 + T | 0.06 (0.06-0.11)b | 0.70 (0.26-1.03)j | 0.06 (0.04-0.08)f | 0.27 (0.13-0.69)g | <.001<.001 |
Data are presented as median (interquartile range). Boldface indicates statistical significance.
Abbreviations: A4, androstenedione; E1, estrone; E2, estradiol; HT, hormone therapy; HT−, nonusers of HT; HT+, users of HT; Sc AT, subcutaneous adipose tissue; T, testosterone; Visc AT, visceral adipose tissue.
aIndependent-samples Mann-Whitney U test.
bn = 11.
cn = 21.
dn = 13.
en = 38.
fn = 10.
gn = 22.
hn = 9.
in = 24.
jn = 8.
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