Patient characteristics and coronary angiography results according to the presence of symptoms (chest pain or dyspnoea)
| . | Asymptomatic (n = 99) . | Symptomatic (n = 75) . | P-value . |
|---|---|---|---|
| Gender (n, %) | 40 (40) | 39 (52) | NS |
| Age [mean (SD)] | 71 (7) | 71 (9.44) | NS |
| PTP [mean (SD)] | 0.17 (0.07) | 0.22 (0.11) | <0.001 |
| Cardiovascular risk factors and comorbidities | |||
| Hypertension (n, %) | 69 (70) | 53 (71) | NS |
| Diabetes (n, %) | 34 (34) | 14 (19) | 0.034 |
| Tobacco (n, %) | 33 (33) | 23 (31) | NS |
| Dyslipidaemia (n, %) | 49 (49) | 29 (39) | NS |
| PAD (n, %) | 13 (13) | 5 (7) | NS |
| Weight | |||
| BMI [mean (SD)] | 27.2 (5.6) | 28.4 (5.7) | NS |
| Obesity (n, %) | 31 (31) | 27 (36) | NS |
| Overweight (n, %) | 31 (31) | 30 (40) | |
| Normal weight (n, %) | 37 (37) | 18 (24) | |
| Insulin (n, %) | 3 (3) | 3 (4) | NS |
| OAD (n, %) | 15 (15) | 8 (11) | NS |
| AF (n, %) | 11 (11) | 16 (21) | NS |
| Left ventricular function | |||
| LVEF stress (%) [mean (SD)] | 65 (13) | 65 (16) | NS |
| LVEF rest (%) [mean (SD)] | 62 (13) | 60 (15) | NS |
| EDV stress (mL) [mean (SD)] | 105 (38) | 107 (40) | NS |
| EDV rest (mL) [mean (SD)] | 103 (38) | 102 (40) | NS |
| ESV stress (mL) [mean (SD)] | 41 (31) | 43 (33) | NS |
| ESV rest (mL) [mean (SD)] | 43 (31) | 44 (33) | NS |
| MBF and MFR | |||
| MBF stress (mL/min/g) [mean (SD)] | 3.04 (0.9) | 2.86 (1.0) | NS |
| MBF rest (mL/min/g) [mean (SD)] | 1.19 (0.4) | 1.08 (0.4) | NS |
| MFR [mean (SD)] | 2.7 (0.7) | 2.8 (0.7) | NS |
| MFR < 2.1 (n, %) | 10 (10) | 8 (11) | NS |
| Perfusion SPECT | |||
| Normal SPECT | 88 (89) | 69 (92) | NS |
| Reversible defects | 3 (3) | 1 (1) | |
| Fixed defects | 7 (7) | 5 (7) | |
| Reversible and fixed defects | 1 (1) | 0 (0) | |
| Coronary angiography | |||
| Referred to coronary angio (n, %) | 10 (10) | 7 (9) | NS |
| Significant CAD (n, %) | 2 (2) | 2 (3) | — |
| Coronary lesions | |||
| LM (n, %) | 0 (0) | 0 (0) | — |
| LAD (n, %) | 1 (10) | 1 (14) | — |
| LCX (n, %) | 0 (0) | 1 (14) | — |
| RCA (n, %) | 2 (20) | 1 (14) | — |
| MVD (n, %) | 1 (50) | 1 (50) | — |
| PCI (n, %) | 1 (10) | 2 (27) | — |
| . | Asymptomatic (n = 99) . | Symptomatic (n = 75) . | P-value . |
|---|---|---|---|
| Gender (n, %) | 40 (40) | 39 (52) | NS |
| Age [mean (SD)] | 71 (7) | 71 (9.44) | NS |
| PTP [mean (SD)] | 0.17 (0.07) | 0.22 (0.11) | <0.001 |
| Cardiovascular risk factors and comorbidities | |||
| Hypertension (n, %) | 69 (70) | 53 (71) | NS |
| Diabetes (n, %) | 34 (34) | 14 (19) | 0.034 |
| Tobacco (n, %) | 33 (33) | 23 (31) | NS |
| Dyslipidaemia (n, %) | 49 (49) | 29 (39) | NS |
| PAD (n, %) | 13 (13) | 5 (7) | NS |
| Weight | |||
| BMI [mean (SD)] | 27.2 (5.6) | 28.4 (5.7) | NS |
| Obesity (n, %) | 31 (31) | 27 (36) | NS |
| Overweight (n, %) | 31 (31) | 30 (40) | |
| Normal weight (n, %) | 37 (37) | 18 (24) | |
| Insulin (n, %) | 3 (3) | 3 (4) | NS |
| OAD (n, %) | 15 (15) | 8 (11) | NS |
| AF (n, %) | 11 (11) | 16 (21) | NS |
| Left ventricular function | |||
| LVEF stress (%) [mean (SD)] | 65 (13) | 65 (16) | NS |
| LVEF rest (%) [mean (SD)] | 62 (13) | 60 (15) | NS |
| EDV stress (mL) [mean (SD)] | 105 (38) | 107 (40) | NS |
| EDV rest (mL) [mean (SD)] | 103 (38) | 102 (40) | NS |
| ESV stress (mL) [mean (SD)] | 41 (31) | 43 (33) | NS |
| ESV rest (mL) [mean (SD)] | 43 (31) | 44 (33) | NS |
| MBF and MFR | |||
| MBF stress (mL/min/g) [mean (SD)] | 3.04 (0.9) | 2.86 (1.0) | NS |
| MBF rest (mL/min/g) [mean (SD)] | 1.19 (0.4) | 1.08 (0.4) | NS |
| MFR [mean (SD)] | 2.7 (0.7) | 2.8 (0.7) | NS |
| MFR < 2.1 (n, %) | 10 (10) | 8 (11) | NS |
| Perfusion SPECT | |||
| Normal SPECT | 88 (89) | 69 (92) | NS |
| Reversible defects | 3 (3) | 1 (1) | |
| Fixed defects | 7 (7) | 5 (7) | |
| Reversible and fixed defects | 1 (1) | 0 (0) | |
| Coronary angiography | |||
| Referred to coronary angio (n, %) | 10 (10) | 7 (9) | NS |
| Significant CAD (n, %) | 2 (2) | 2 (3) | — |
| Coronary lesions | |||
| LM (n, %) | 0 (0) | 0 (0) | — |
| LAD (n, %) | 1 (10) | 1 (14) | — |
| LCX (n, %) | 0 (0) | 1 (14) | — |
| RCA (n, %) | 2 (20) | 1 (14) | — |
| MVD (n, %) | 1 (50) | 1 (50) | — |
| PCI (n, %) | 1 (10) | 2 (27) | — |
PAD, peripheral artery disease; BMI, body mass index; OAD, oral antidiabetic drugs; AF, atrial fibrillation; LVEF, left ventricular ejection fraction; EDV, end-diastolic volume; ESV, end-systolic volume; LM, left main trunk; LAD, left anterior descending artery; LCX, left circumflex artery; RCA, right coronary artery; MVD, multivessel disease; PCI, percutaneous intervention.
Patient characteristics and coronary angiography results according to the presence of symptoms (chest pain or dyspnoea)
| . | Asymptomatic (n = 99) . | Symptomatic (n = 75) . | P-value . |
|---|---|---|---|
| Gender (n, %) | 40 (40) | 39 (52) | NS |
| Age [mean (SD)] | 71 (7) | 71 (9.44) | NS |
| PTP [mean (SD)] | 0.17 (0.07) | 0.22 (0.11) | <0.001 |
| Cardiovascular risk factors and comorbidities | |||
| Hypertension (n, %) | 69 (70) | 53 (71) | NS |
| Diabetes (n, %) | 34 (34) | 14 (19) | 0.034 |
| Tobacco (n, %) | 33 (33) | 23 (31) | NS |
| Dyslipidaemia (n, %) | 49 (49) | 29 (39) | NS |
| PAD (n, %) | 13 (13) | 5 (7) | NS |
| Weight | |||
| BMI [mean (SD)] | 27.2 (5.6) | 28.4 (5.7) | NS |
| Obesity (n, %) | 31 (31) | 27 (36) | NS |
| Overweight (n, %) | 31 (31) | 30 (40) | |
| Normal weight (n, %) | 37 (37) | 18 (24) | |
| Insulin (n, %) | 3 (3) | 3 (4) | NS |
| OAD (n, %) | 15 (15) | 8 (11) | NS |
| AF (n, %) | 11 (11) | 16 (21) | NS |
| Left ventricular function | |||
| LVEF stress (%) [mean (SD)] | 65 (13) | 65 (16) | NS |
| LVEF rest (%) [mean (SD)] | 62 (13) | 60 (15) | NS |
| EDV stress (mL) [mean (SD)] | 105 (38) | 107 (40) | NS |
| EDV rest (mL) [mean (SD)] | 103 (38) | 102 (40) | NS |
| ESV stress (mL) [mean (SD)] | 41 (31) | 43 (33) | NS |
| ESV rest (mL) [mean (SD)] | 43 (31) | 44 (33) | NS |
| MBF and MFR | |||
| MBF stress (mL/min/g) [mean (SD)] | 3.04 (0.9) | 2.86 (1.0) | NS |
| MBF rest (mL/min/g) [mean (SD)] | 1.19 (0.4) | 1.08 (0.4) | NS |
| MFR [mean (SD)] | 2.7 (0.7) | 2.8 (0.7) | NS |
| MFR < 2.1 (n, %) | 10 (10) | 8 (11) | NS |
| Perfusion SPECT | |||
| Normal SPECT | 88 (89) | 69 (92) | NS |
| Reversible defects | 3 (3) | 1 (1) | |
| Fixed defects | 7 (7) | 5 (7) | |
| Reversible and fixed defects | 1 (1) | 0 (0) | |
| Coronary angiography | |||
| Referred to coronary angio (n, %) | 10 (10) | 7 (9) | NS |
| Significant CAD (n, %) | 2 (2) | 2 (3) | — |
| Coronary lesions | |||
| LM (n, %) | 0 (0) | 0 (0) | — |
| LAD (n, %) | 1 (10) | 1 (14) | — |
| LCX (n, %) | 0 (0) | 1 (14) | — |
| RCA (n, %) | 2 (20) | 1 (14) | — |
| MVD (n, %) | 1 (50) | 1 (50) | — |
| PCI (n, %) | 1 (10) | 2 (27) | — |
| . | Asymptomatic (n = 99) . | Symptomatic (n = 75) . | P-value . |
|---|---|---|---|
| Gender (n, %) | 40 (40) | 39 (52) | NS |
| Age [mean (SD)] | 71 (7) | 71 (9.44) | NS |
| PTP [mean (SD)] | 0.17 (0.07) | 0.22 (0.11) | <0.001 |
| Cardiovascular risk factors and comorbidities | |||
| Hypertension (n, %) | 69 (70) | 53 (71) | NS |
| Diabetes (n, %) | 34 (34) | 14 (19) | 0.034 |
| Tobacco (n, %) | 33 (33) | 23 (31) | NS |
| Dyslipidaemia (n, %) | 49 (49) | 29 (39) | NS |
| PAD (n, %) | 13 (13) | 5 (7) | NS |
| Weight | |||
| BMI [mean (SD)] | 27.2 (5.6) | 28.4 (5.7) | NS |
| Obesity (n, %) | 31 (31) | 27 (36) | NS |
| Overweight (n, %) | 31 (31) | 30 (40) | |
| Normal weight (n, %) | 37 (37) | 18 (24) | |
| Insulin (n, %) | 3 (3) | 3 (4) | NS |
| OAD (n, %) | 15 (15) | 8 (11) | NS |
| AF (n, %) | 11 (11) | 16 (21) | NS |
| Left ventricular function | |||
| LVEF stress (%) [mean (SD)] | 65 (13) | 65 (16) | NS |
| LVEF rest (%) [mean (SD)] | 62 (13) | 60 (15) | NS |
| EDV stress (mL) [mean (SD)] | 105 (38) | 107 (40) | NS |
| EDV rest (mL) [mean (SD)] | 103 (38) | 102 (40) | NS |
| ESV stress (mL) [mean (SD)] | 41 (31) | 43 (33) | NS |
| ESV rest (mL) [mean (SD)] | 43 (31) | 44 (33) | NS |
| MBF and MFR | |||
| MBF stress (mL/min/g) [mean (SD)] | 3.04 (0.9) | 2.86 (1.0) | NS |
| MBF rest (mL/min/g) [mean (SD)] | 1.19 (0.4) | 1.08 (0.4) | NS |
| MFR [mean (SD)] | 2.7 (0.7) | 2.8 (0.7) | NS |
| MFR < 2.1 (n, %) | 10 (10) | 8 (11) | NS |
| Perfusion SPECT | |||
| Normal SPECT | 88 (89) | 69 (92) | NS |
| Reversible defects | 3 (3) | 1 (1) | |
| Fixed defects | 7 (7) | 5 (7) | |
| Reversible and fixed defects | 1 (1) | 0 (0) | |
| Coronary angiography | |||
| Referred to coronary angio (n, %) | 10 (10) | 7 (9) | NS |
| Significant CAD (n, %) | 2 (2) | 2 (3) | — |
| Coronary lesions | |||
| LM (n, %) | 0 (0) | 0 (0) | — |
| LAD (n, %) | 1 (10) | 1 (14) | — |
| LCX (n, %) | 0 (0) | 1 (14) | — |
| RCA (n, %) | 2 (20) | 1 (14) | — |
| MVD (n, %) | 1 (50) | 1 (50) | — |
| PCI (n, %) | 1 (10) | 2 (27) | — |
PAD, peripheral artery disease; BMI, body mass index; OAD, oral antidiabetic drugs; AF, atrial fibrillation; LVEF, left ventricular ejection fraction; EDV, end-diastolic volume; ESV, end-systolic volume; LM, left main trunk; LAD, left anterior descending artery; LCX, left circumflex artery; RCA, right coronary artery; MVD, multivessel disease; PCI, percutaneous intervention.
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