Table 1.
Open in new tab

Sample Characteristics

GROUPSCOPECombined Dataset
Age; mean (SD)
 SSD27.36 (7.45)39.91 (12.48)31.05 (10.84)
 ASC—24.28 (6.18)24.28 (6.18)
 SSD-siblings30.85 (7.92)—30.85 (7.92)
 TC34.4 (10.67)—34.4 (10.67)
 Statistical significance between participant groups in Combined DatasetH(3) = 105.43, P < .001, η2 [H] = 0.04
Gender; n male (%)
 SSD789 (77.2)288 (67.6)1077 (74.4)
 ASC—92 (89.3)92 (89.3)
 SSD-siblings310 (44.3)—310 (44.3)
 TC186 (45.5)—186 (45.5)
 Statistical significance between participant groups in Combined DatasetX2(3, n = 2660) = 268.70, P < .001, V = 0.30
PANSS Total; mean (SD)
 SSD54.41 (16.80)62.86 (14.62)56.97 (16.62)
 ASC—46.02 (8.06)46.02 (8.06)
 SSD-siblings32.29 (4.23)—32.29 (4.23)
 TC31.57 (2.86)—31.57 (2.86)
 Statistical significance between participant groups in Combined DatasetH(3) = 1659.12, P < .001, η2 [H] = 0.64
PANSS Positive; mean (SD)
 SSD12.69 (5.31)16.37 (5.27)13.78 (5.55)
 ASC—9.89 (2.98)9.89 (2.98)
 SSD-siblings7.30 (1.00)—7.30 (1.00)
 TC7.27 (0.83)—7.27 (0.83)
 Statistical significance between participant groups in Combined DatasetH(3) = 1389.39, P < .001, η2 [H] = 0.53
PANSS Negative; mean (SD)
 SSD13.90 (5.90)14.29 (5.31)14.02 (5.74)
 ASC—12.81 (4.73)12.81 (4.73)
 SSD-siblings7.58 (1.65)—7.58 (1.65)
 TC7.25 (0.68)—7.25 (0.68)
 Statistical significance between participant groups in Combined DatasetH(3) = 1346.71, P < .001, η2 [H] = 0.51
PANSS General; mean (SD)
 SSD27.89 (8.40)32.20 (7.98)29.19 (8.51)
 ASC—23.32 (4.81)23.32 (4.81)
 SSD-siblings17.43 (2.63)—17.43 (2.63)
 TC17.05 (2.11)—17.05 (2.11)
 Statistical significance between participant groups in Combined DatasetH(3) = 1522.39, P < .001, η2 [H] = 0.58
PAUSS total; mean (SD)
 SSD14.56 (5.70)15.52 (5.21)14.84 (5.57)
 ASC—13.85 (4.23)13.85 (4.23)
 SSD-siblings8.54 (1.53)—8.54 (1.53)
 TC8.23 (0.69)—8.23 (0.69)
 Statistical significance between participant groups in Combined DatasetH(3) = 1369.79, P < .001, η2 [H] = 0.51
GROUPSCOPECombined Dataset
Age; mean (SD)
 SSD27.36 (7.45)39.91 (12.48)31.05 (10.84)
 ASC—24.28 (6.18)24.28 (6.18)
 SSD-siblings30.85 (7.92)—30.85 (7.92)
 TC34.4 (10.67)—34.4 (10.67)
 Statistical significance between participant groups in Combined DatasetH(3) = 105.43, P < .001, η2 [H] = 0.04
Gender; n male (%)
 SSD789 (77.2)288 (67.6)1077 (74.4)
 ASC—92 (89.3)92 (89.3)
 SSD-siblings310 (44.3)—310 (44.3)
 TC186 (45.5)—186 (45.5)
 Statistical significance between participant groups in Combined DatasetX2(3, n = 2660) = 268.70, P < .001, V = 0.30
PANSS Total; mean (SD)
 SSD54.41 (16.80)62.86 (14.62)56.97 (16.62)
 ASC—46.02 (8.06)46.02 (8.06)
 SSD-siblings32.29 (4.23)—32.29 (4.23)
 TC31.57 (2.86)—31.57 (2.86)
 Statistical significance between participant groups in Combined DatasetH(3) = 1659.12, P < .001, η2 [H] = 0.64
PANSS Positive; mean (SD)
 SSD12.69 (5.31)16.37 (5.27)13.78 (5.55)
 ASC—9.89 (2.98)9.89 (2.98)
 SSD-siblings7.30 (1.00)—7.30 (1.00)
 TC7.27 (0.83)—7.27 (0.83)
 Statistical significance between participant groups in Combined DatasetH(3) = 1389.39, P < .001, η2 [H] = 0.53
PANSS Negative; mean (SD)
 SSD13.90 (5.90)14.29 (5.31)14.02 (5.74)
 ASC—12.81 (4.73)12.81 (4.73)
 SSD-siblings7.58 (1.65)—7.58 (1.65)
 TC7.25 (0.68)—7.25 (0.68)
 Statistical significance between participant groups in Combined DatasetH(3) = 1346.71, P < .001, η2 [H] = 0.51
PANSS General; mean (SD)
 SSD27.89 (8.40)32.20 (7.98)29.19 (8.51)
 ASC—23.32 (4.81)23.32 (4.81)
 SSD-siblings17.43 (2.63)—17.43 (2.63)
 TC17.05 (2.11)—17.05 (2.11)
 Statistical significance between participant groups in Combined DatasetH(3) = 1522.39, P < .001, η2 [H] = 0.58
PAUSS total; mean (SD)
 SSD14.56 (5.70)15.52 (5.21)14.84 (5.57)
 ASC—13.85 (4.23)13.85 (4.23)
 SSD-siblings8.54 (1.53)—8.54 (1.53)
 TC8.23 (0.69)—8.23 (0.69)
 Statistical significance between participant groups in Combined DatasetH(3) = 1369.79, P < .001, η2 [H] = 0.51

Note: ASC, autism spectrum condition; PANSS, Positive and Negative Syndrome Scale; PAUSS, PANSS-Autism-Severity-Score; SSD, schizophrenia spectrum disorder; TC, typical control.

Table 1.
Open in new tab

Sample Characteristics

GROUPSCOPECombined Dataset
Age; mean (SD)
 SSD27.36 (7.45)39.91 (12.48)31.05 (10.84)
 ASC—24.28 (6.18)24.28 (6.18)
 SSD-siblings30.85 (7.92)—30.85 (7.92)
 TC34.4 (10.67)—34.4 (10.67)
 Statistical significance between participant groups in Combined DatasetH(3) = 105.43, P < .001, η2 [H] = 0.04
Gender; n male (%)
 SSD789 (77.2)288 (67.6)1077 (74.4)
 ASC—92 (89.3)92 (89.3)
 SSD-siblings310 (44.3)—310 (44.3)
 TC186 (45.5)—186 (45.5)
 Statistical significance between participant groups in Combined DatasetX2(3, n = 2660) = 268.70, P < .001, V = 0.30
PANSS Total; mean (SD)
 SSD54.41 (16.80)62.86 (14.62)56.97 (16.62)
 ASC—46.02 (8.06)46.02 (8.06)
 SSD-siblings32.29 (4.23)—32.29 (4.23)
 TC31.57 (2.86)—31.57 (2.86)
 Statistical significance between participant groups in Combined DatasetH(3) = 1659.12, P < .001, η2 [H] = 0.64
PANSS Positive; mean (SD)
 SSD12.69 (5.31)16.37 (5.27)13.78 (5.55)
 ASC—9.89 (2.98)9.89 (2.98)
 SSD-siblings7.30 (1.00)—7.30 (1.00)
 TC7.27 (0.83)—7.27 (0.83)
 Statistical significance between participant groups in Combined DatasetH(3) = 1389.39, P < .001, η2 [H] = 0.53
PANSS Negative; mean (SD)
 SSD13.90 (5.90)14.29 (5.31)14.02 (5.74)
 ASC—12.81 (4.73)12.81 (4.73)
 SSD-siblings7.58 (1.65)—7.58 (1.65)
 TC7.25 (0.68)—7.25 (0.68)
 Statistical significance between participant groups in Combined DatasetH(3) = 1346.71, P < .001, η2 [H] = 0.51
PANSS General; mean (SD)
 SSD27.89 (8.40)32.20 (7.98)29.19 (8.51)
 ASC—23.32 (4.81)23.32 (4.81)
 SSD-siblings17.43 (2.63)—17.43 (2.63)
 TC17.05 (2.11)—17.05 (2.11)
 Statistical significance between participant groups in Combined DatasetH(3) = 1522.39, P < .001, η2 [H] = 0.58
PAUSS total; mean (SD)
 SSD14.56 (5.70)15.52 (5.21)14.84 (5.57)
 ASC—13.85 (4.23)13.85 (4.23)
 SSD-siblings8.54 (1.53)—8.54 (1.53)
 TC8.23 (0.69)—8.23 (0.69)
 Statistical significance between participant groups in Combined DatasetH(3) = 1369.79, P < .001, η2 [H] = 0.51
GROUPSCOPECombined Dataset
Age; mean (SD)
 SSD27.36 (7.45)39.91 (12.48)31.05 (10.84)
 ASC—24.28 (6.18)24.28 (6.18)
 SSD-siblings30.85 (7.92)—30.85 (7.92)
 TC34.4 (10.67)—34.4 (10.67)
 Statistical significance between participant groups in Combined DatasetH(3) = 105.43, P < .001, η2 [H] = 0.04
Gender; n male (%)
 SSD789 (77.2)288 (67.6)1077 (74.4)
 ASC—92 (89.3)92 (89.3)
 SSD-siblings310 (44.3)—310 (44.3)
 TC186 (45.5)—186 (45.5)
 Statistical significance between participant groups in Combined DatasetX2(3, n = 2660) = 268.70, P < .001, V = 0.30
PANSS Total; mean (SD)
 SSD54.41 (16.80)62.86 (14.62)56.97 (16.62)
 ASC—46.02 (8.06)46.02 (8.06)
 SSD-siblings32.29 (4.23)—32.29 (4.23)
 TC31.57 (2.86)—31.57 (2.86)
 Statistical significance between participant groups in Combined DatasetH(3) = 1659.12, P < .001, η2 [H] = 0.64
PANSS Positive; mean (SD)
 SSD12.69 (5.31)16.37 (5.27)13.78 (5.55)
 ASC—9.89 (2.98)9.89 (2.98)
 SSD-siblings7.30 (1.00)—7.30 (1.00)
 TC7.27 (0.83)—7.27 (0.83)
 Statistical significance between participant groups in Combined DatasetH(3) = 1389.39, P < .001, η2 [H] = 0.53
PANSS Negative; mean (SD)
 SSD13.90 (5.90)14.29 (5.31)14.02 (5.74)
 ASC—12.81 (4.73)12.81 (4.73)
 SSD-siblings7.58 (1.65)—7.58 (1.65)
 TC7.25 (0.68)—7.25 (0.68)
 Statistical significance between participant groups in Combined DatasetH(3) = 1346.71, P < .001, η2 [H] = 0.51
PANSS General; mean (SD)
 SSD27.89 (8.40)32.20 (7.98)29.19 (8.51)
 ASC—23.32 (4.81)23.32 (4.81)
 SSD-siblings17.43 (2.63)—17.43 (2.63)
 TC17.05 (2.11)—17.05 (2.11)
 Statistical significance between participant groups in Combined DatasetH(3) = 1522.39, P < .001, η2 [H] = 0.58
PAUSS total; mean (SD)
 SSD14.56 (5.70)15.52 (5.21)14.84 (5.57)
 ASC—13.85 (4.23)13.85 (4.23)
 SSD-siblings8.54 (1.53)—8.54 (1.53)
 TC8.23 (0.69)—8.23 (0.69)
 Statistical significance between participant groups in Combined DatasetH(3) = 1369.79, P < .001, η2 [H] = 0.51

Note: ASC, autism spectrum condition; PANSS, Positive and Negative Syndrome Scale; PAUSS, PANSS-Autism-Severity-Score; SSD, schizophrenia spectrum disorder; TC, typical control.

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