Table 3.
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Premorbid Social Adjustment: Fixed Effect Estimates From Growth Curve Models Estimating Premorbid Social Adjustment as a Function of Conversion Status (Converted vs Not Converted) and Clinical Covariates in 498 Youth at Clinical High Risk for Psychosis [With 95% Confidence Intervals]

Clinical Covariate
Attenuated Negative SymptomsVerbal LearningPresence of Childhood TraumaImpact of Childhood Trauma
Within-person
 Time0.17***
[0.10, 0.23]		0.16***
[0.09, 0.24]		0.16**
[0.06, 0.27]		0.15**
[0.03, 0.27]
Between-person
 Age−0.02
[−0.04, 0.01]		−0.01
[−0.04, 0.02]		−0.03
[−0.06, 0.00]		−0.03
[−0.07, 0.01]
 Sex0.10
[−0.07, 0.28]		0.03
[−0.16, 0.23]		0.05
[−0.14, 0.24]		−0.01
[−0.28, 0.27]
 Conversion0.07
[−0.23, 0.37]		0.32
[−0.01, 0.64]		0.27
[−0.17, 0.70]		0.44*
[0.01, 0.88]
 Covariate0.37***
[0.30, 0.45]		−0.00
[−0.02, 0.02]		0.28**
[0.07, 0.49]		0.04*
[0.00, 0.08]
Interactions
 Conversion × Time0.03
[−0.20, 0.26]		0.03
[−0.21, 0.26]		−0.09
[−0.22, 0.40]		0.05
[−0.28, 0.38]
 Covariate × Conversion0.11
[−0.11, 0.33]		0.05
[−0.00, 0.11]		−0.12
[−0.48, 0.74]		−0.07
[−0.15, 0.01]
 Covariate × Time0.18***,c
[0.12, 0.24]		−0.02**,a
[−0.03, −0.01]		−0.00
[−0.15, 0.14]		−0.01
[−0.04, 0.02]
 Covariate × Conversion × Time−0.17†
[−0.34, −0.00]		−0.01
[−0.05, 0.03]		−0.10
[−0.56, 0.34]		−0.02
[−0.08, 0.04]
Clinical Covariate
Attenuated Negative SymptomsVerbal LearningPresence of Childhood TraumaImpact of Childhood Trauma
Within-person
 Time0.17***
[0.10, 0.23]		0.16***
[0.09, 0.24]		0.16**
[0.06, 0.27]		0.15**
[0.03, 0.27]
Between-person
 Age−0.02
[−0.04, 0.01]		−0.01
[−0.04, 0.02]		−0.03
[−0.06, 0.00]		−0.03
[−0.07, 0.01]
 Sex0.10
[−0.07, 0.28]		0.03
[−0.16, 0.23]		0.05
[−0.14, 0.24]		−0.01
[−0.28, 0.27]
 Conversion0.07
[−0.23, 0.37]		0.32
[−0.01, 0.64]		0.27
[−0.17, 0.70]		0.44*
[0.01, 0.88]
 Covariate0.37***
[0.30, 0.45]		−0.00
[−0.02, 0.02]		0.28**
[0.07, 0.49]		0.04*
[0.00, 0.08]
Interactions
 Conversion × Time0.03
[−0.20, 0.26]		0.03
[−0.21, 0.26]		−0.09
[−0.22, 0.40]		0.05
[−0.28, 0.38]
 Covariate × Conversion0.11
[−0.11, 0.33]		0.05
[−0.00, 0.11]		−0.12
[−0.48, 0.74]		−0.07
[−0.15, 0.01]
 Covariate × Time0.18***,c
[0.12, 0.24]		−0.02**,a
[−0.03, −0.01]		−0.00
[−0.15, 0.14]		−0.01
[−0.04, 0.02]
 Covariate × Conversion × Time−0.17†
[−0.34, −0.00]		−0.01
[−0.05, 0.03]		−0.10
[−0.56, 0.34]		−0.02
[−0.08, 0.04]

Note: Bold indicates uncorrected P < .05. To minimize inflation of the Type II error rate, FDR correction was limited to tests of focal hypotheses (interactions).

aFDR-corrected P < .05.

bFDR-corrected P < .001.

*Uncorrected P < .05; **uncorrected P < .01; ***uncorrected P < .001.

†Uncorrected P = .051.

Table 3.
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Premorbid Social Adjustment: Fixed Effect Estimates From Growth Curve Models Estimating Premorbid Social Adjustment as a Function of Conversion Status (Converted vs Not Converted) and Clinical Covariates in 498 Youth at Clinical High Risk for Psychosis [With 95% Confidence Intervals]

Clinical Covariate
Attenuated Negative SymptomsVerbal LearningPresence of Childhood TraumaImpact of Childhood Trauma
Within-person
 Time0.17***
[0.10, 0.23]		0.16***
[0.09, 0.24]		0.16**
[0.06, 0.27]		0.15**
[0.03, 0.27]
Between-person
 Age−0.02
[−0.04, 0.01]		−0.01
[−0.04, 0.02]		−0.03
[−0.06, 0.00]		−0.03
[−0.07, 0.01]
 Sex0.10
[−0.07, 0.28]		0.03
[−0.16, 0.23]		0.05
[−0.14, 0.24]		−0.01
[−0.28, 0.27]
 Conversion0.07
[−0.23, 0.37]		0.32
[−0.01, 0.64]		0.27
[−0.17, 0.70]		0.44*
[0.01, 0.88]
 Covariate0.37***
[0.30, 0.45]		−0.00
[−0.02, 0.02]		0.28**
[0.07, 0.49]		0.04*
[0.00, 0.08]
Interactions
 Conversion × Time0.03
[−0.20, 0.26]		0.03
[−0.21, 0.26]		−0.09
[−0.22, 0.40]		0.05
[−0.28, 0.38]
 Covariate × Conversion0.11
[−0.11, 0.33]		0.05
[−0.00, 0.11]		−0.12
[−0.48, 0.74]		−0.07
[−0.15, 0.01]
 Covariate × Time0.18***,c
[0.12, 0.24]		−0.02**,a
[−0.03, −0.01]		−0.00
[−0.15, 0.14]		−0.01
[−0.04, 0.02]
 Covariate × Conversion × Time−0.17†
[−0.34, −0.00]		−0.01
[−0.05, 0.03]		−0.10
[−0.56, 0.34]		−0.02
[−0.08, 0.04]
Clinical Covariate
Attenuated Negative SymptomsVerbal LearningPresence of Childhood TraumaImpact of Childhood Trauma
Within-person
 Time0.17***
[0.10, 0.23]		0.16***
[0.09, 0.24]		0.16**
[0.06, 0.27]		0.15**
[0.03, 0.27]
Between-person
 Age−0.02
[−0.04, 0.01]		−0.01
[−0.04, 0.02]		−0.03
[−0.06, 0.00]		−0.03
[−0.07, 0.01]
 Sex0.10
[−0.07, 0.28]		0.03
[−0.16, 0.23]		0.05
[−0.14, 0.24]		−0.01
[−0.28, 0.27]
 Conversion0.07
[−0.23, 0.37]		0.32
[−0.01, 0.64]		0.27
[−0.17, 0.70]		0.44*
[0.01, 0.88]
 Covariate0.37***
[0.30, 0.45]		−0.00
[−0.02, 0.02]		0.28**
[0.07, 0.49]		0.04*
[0.00, 0.08]
Interactions
 Conversion × Time0.03
[−0.20, 0.26]		0.03
[−0.21, 0.26]		−0.09
[−0.22, 0.40]		0.05
[−0.28, 0.38]
 Covariate × Conversion0.11
[−0.11, 0.33]		0.05
[−0.00, 0.11]		−0.12
[−0.48, 0.74]		−0.07
[−0.15, 0.01]
 Covariate × Time0.18***,c
[0.12, 0.24]		−0.02**,a
[−0.03, −0.01]		−0.00
[−0.15, 0.14]		−0.01
[−0.04, 0.02]
 Covariate × Conversion × Time−0.17†
[−0.34, −0.00]		−0.01
[−0.05, 0.03]		−0.10
[−0.56, 0.34]		−0.02
[−0.08, 0.04]

Note: Bold indicates uncorrected P < .05. To minimize inflation of the Type II error rate, FDR correction was limited to tests of focal hypotheses (interactions).

aFDR-corrected P < .05.

bFDR-corrected P < .001.

*Uncorrected P < .05; **uncorrected P < .01; ***uncorrected P < .001.

†Uncorrected P = .051.

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