Clinical Characteristics, Risk Factors, and Outcomes of Slow-Growing and Rapidly Growing NTM Endocarditis
| . | NTM Endocarditis, No. (%) . | . | |
|---|---|---|---|
| Variable . | Slow Growing (n = 68) . | Rapidly Growing (n = 99) . | P Value . |
| Gender | 58/68 (85.3) | 67/99 (67.7) | .010 |
| Mean ± SD | |||
| Age, y | 56 ± 14 | 47 ± 18 | .001 |
| Duration of illness, d | 140 ± 21 | 60.7 ± 41.1 | .005 |
| C-reactive protein, mg/dL | 67 ± 14.8 | 84 ± 13 | .408 |
| Endocarditis | |||
| Right side | 0/68 (0) | 15/80 (18.75) | <.001 |
| Aortic valve | 48/68 (70.6) | 41/80 (51.2) | .016 |
| Valve IE | |||
| Prosthetic | 57/68 (83.8) | 49/99 (49.5) | <.001 |
| Early prosthetic | 22/57 (38.6) | 31/49 (63.3) | .011 |
| Native | 1/28 (3.6) | 27/28 (96.4) | <.001 |
| Paravalvular complications | 16/68 (23.5) | 32/86 (37.2) | .068 |
| Peripheral emboli | 15/68 (22.1) | 24/99 (24.2) | .743 |
| Disseminated disease | 59/68 (86.8) | 82/99 (82.8) | .490 |
| Mean ± SD | |||
| Vegetation size, mm | 11 ± 4.8 | 14.5 ± 10.8 | .415 |
| Duration of antibiotics, d | 357± 49 | 219 ± 89 | .012 |
| Surgery for IE | 46/66 (69.7) | 55/99 (55.6) | .067 |
| Relapse | 6/34 (17.6) | 1/52 (1.9) | .009 |
| Mortality | 28/68 (41.2) | 47/99 (47.5) | .421 |
| . | NTM Endocarditis, No. (%) . | . | |
|---|---|---|---|
| Variable . | Slow Growing (n = 68) . | Rapidly Growing (n = 99) . | P Value . |
| Gender | 58/68 (85.3) | 67/99 (67.7) | .010 |
| Mean ± SD | |||
| Age, y | 56 ± 14 | 47 ± 18 | .001 |
| Duration of illness, d | 140 ± 21 | 60.7 ± 41.1 | .005 |
| C-reactive protein, mg/dL | 67 ± 14.8 | 84 ± 13 | .408 |
| Endocarditis | |||
| Right side | 0/68 (0) | 15/80 (18.75) | <.001 |
| Aortic valve | 48/68 (70.6) | 41/80 (51.2) | .016 |
| Valve IE | |||
| Prosthetic | 57/68 (83.8) | 49/99 (49.5) | <.001 |
| Early prosthetic | 22/57 (38.6) | 31/49 (63.3) | .011 |
| Native | 1/28 (3.6) | 27/28 (96.4) | <.001 |
| Paravalvular complications | 16/68 (23.5) | 32/86 (37.2) | .068 |
| Peripheral emboli | 15/68 (22.1) | 24/99 (24.2) | .743 |
| Disseminated disease | 59/68 (86.8) | 82/99 (82.8) | .490 |
| Mean ± SD | |||
| Vegetation size, mm | 11 ± 4.8 | 14.5 ± 10.8 | .415 |
| Duration of antibiotics, d | 357± 49 | 219 ± 89 | .012 |
| Surgery for IE | 46/66 (69.7) | 55/99 (55.6) | .067 |
| Relapse | 6/34 (17.6) | 1/52 (1.9) | .009 |
| Mortality | 28/68 (41.2) | 47/99 (47.5) | .421 |
Abbreviations: IE, infective endocarditis; NTM, nontuberculous mycobacteria.
Clinical Characteristics, Risk Factors, and Outcomes of Slow-Growing and Rapidly Growing NTM Endocarditis
| . | NTM Endocarditis, No. (%) . | . | |
|---|---|---|---|
| Variable . | Slow Growing (n = 68) . | Rapidly Growing (n = 99) . | P Value . |
| Gender | 58/68 (85.3) | 67/99 (67.7) | .010 |
| Mean ± SD | |||
| Age, y | 56 ± 14 | 47 ± 18 | .001 |
| Duration of illness, d | 140 ± 21 | 60.7 ± 41.1 | .005 |
| C-reactive protein, mg/dL | 67 ± 14.8 | 84 ± 13 | .408 |
| Endocarditis | |||
| Right side | 0/68 (0) | 15/80 (18.75) | <.001 |
| Aortic valve | 48/68 (70.6) | 41/80 (51.2) | .016 |
| Valve IE | |||
| Prosthetic | 57/68 (83.8) | 49/99 (49.5) | <.001 |
| Early prosthetic | 22/57 (38.6) | 31/49 (63.3) | .011 |
| Native | 1/28 (3.6) | 27/28 (96.4) | <.001 |
| Paravalvular complications | 16/68 (23.5) | 32/86 (37.2) | .068 |
| Peripheral emboli | 15/68 (22.1) | 24/99 (24.2) | .743 |
| Disseminated disease | 59/68 (86.8) | 82/99 (82.8) | .490 |
| Mean ± SD | |||
| Vegetation size, mm | 11 ± 4.8 | 14.5 ± 10.8 | .415 |
| Duration of antibiotics, d | 357± 49 | 219 ± 89 | .012 |
| Surgery for IE | 46/66 (69.7) | 55/99 (55.6) | .067 |
| Relapse | 6/34 (17.6) | 1/52 (1.9) | .009 |
| Mortality | 28/68 (41.2) | 47/99 (47.5) | .421 |
| . | NTM Endocarditis, No. (%) . | . | |
|---|---|---|---|
| Variable . | Slow Growing (n = 68) . | Rapidly Growing (n = 99) . | P Value . |
| Gender | 58/68 (85.3) | 67/99 (67.7) | .010 |
| Mean ± SD | |||
| Age, y | 56 ± 14 | 47 ± 18 | .001 |
| Duration of illness, d | 140 ± 21 | 60.7 ± 41.1 | .005 |
| C-reactive protein, mg/dL | 67 ± 14.8 | 84 ± 13 | .408 |
| Endocarditis | |||
| Right side | 0/68 (0) | 15/80 (18.75) | <.001 |
| Aortic valve | 48/68 (70.6) | 41/80 (51.2) | .016 |
| Valve IE | |||
| Prosthetic | 57/68 (83.8) | 49/99 (49.5) | <.001 |
| Early prosthetic | 22/57 (38.6) | 31/49 (63.3) | .011 |
| Native | 1/28 (3.6) | 27/28 (96.4) | <.001 |
| Paravalvular complications | 16/68 (23.5) | 32/86 (37.2) | .068 |
| Peripheral emboli | 15/68 (22.1) | 24/99 (24.2) | .743 |
| Disseminated disease | 59/68 (86.8) | 82/99 (82.8) | .490 |
| Mean ± SD | |||
| Vegetation size, mm | 11 ± 4.8 | 14.5 ± 10.8 | .415 |
| Duration of antibiotics, d | 357± 49 | 219 ± 89 | .012 |
| Surgery for IE | 46/66 (69.7) | 55/99 (55.6) | .067 |
| Relapse | 6/34 (17.6) | 1/52 (1.9) | .009 |
| Mortality | 28/68 (41.2) | 47/99 (47.5) | .421 |
Abbreviations: IE, infective endocarditis; NTM, nontuberculous mycobacteria.
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