Table 1.
Open in new tab

Patients and Tumor Characteristics

CharacteristicsIntervention (n = 16)Control (n = 19)P-value
Age, average56.6 y (±19)52.4 y (±14.9)0.344
Sex
 Male11 (68.8%)13 (68.4%)
 Female5 (31.2%)6 (31.6%)
ECOG1.000
 0–19 (56.3%)10 (52.6%)
 2–37 (43.8%)9 (47.4%)
MMSE score, average18.1 (±9.1)23.6 (±5.7)0.054
Extent of resection0.404
 Biopsy8 (50%)7 (36.8%)
 STR5 (31.6%)6 (31.6%)
 NTR2 (12.5%)6 (31.6%)
 GTR1 (6.3%)0
Resectable0.506
 Yes8 (50%)12 (63.2%)
 No8 (50%)7 (36.8%)
Tumor Extension0.018
 Unifocal4 (25%)13 (68.4%)
 Multifocal12 (75%)6 (31.6%)
Laterality of tumor0.379
 Unilateral12 (75%)29 (89.5%)
 Bilateral4 (25%)2 (10.5%)
MGMTa0.695
 Methylated8 (57.1%)6 (42.9%)
 Non-methylated5 (41.7%)7 (58.3%)
IDH mutationa1
 Yes1 (11.1%)3 (21.4%)
 No8 (88.9%)11 (78.6%)
CharacteristicsIntervention (n = 16)Control (n = 19)P-value
Age, average56.6 y (±19)52.4 y (±14.9)0.344
Sex
 Male11 (68.8%)13 (68.4%)
 Female5 (31.2%)6 (31.6%)
ECOG1.000
 0–19 (56.3%)10 (52.6%)
 2–37 (43.8%)9 (47.4%)
MMSE score, average18.1 (±9.1)23.6 (±5.7)0.054
Extent of resection0.404
 Biopsy8 (50%)7 (36.8%)
 STR5 (31.6%)6 (31.6%)
 NTR2 (12.5%)6 (31.6%)
 GTR1 (6.3%)0
Resectable0.506
 Yes8 (50%)12 (63.2%)
 No8 (50%)7 (36.8%)
Tumor Extension0.018
 Unifocal4 (25%)13 (68.4%)
 Multifocal12 (75%)6 (31.6%)
Laterality of tumor0.379
 Unilateral12 (75%)29 (89.5%)
 Bilateral4 (25%)2 (10.5%)
MGMTa0.695
 Methylated8 (57.1%)6 (42.9%)
 Non-methylated5 (41.7%)7 (58.3%)
IDH mutationa1
 Yes1 (11.1%)3 (21.4%)
 No8 (88.9%)11 (78.6%)

Abbreviations: ECOG, Eastern Cooperative Oncology Group; GTR, gross tumor resection; IDH, isocitrate dehydrogenase; MGMT, O6-Methylguanine-DNA Methyltransferase; MMSE, Mini-Mental State Examination; NTR, near-total resection; STR, sub-total resection.

aOut of available cases with molecular testing.

Table 1.
Open in new tab

Patients and Tumor Characteristics

CharacteristicsIntervention (n = 16)Control (n = 19)P-value
Age, average56.6 y (±19)52.4 y (±14.9)0.344
Sex
 Male11 (68.8%)13 (68.4%)
 Female5 (31.2%)6 (31.6%)
ECOG1.000
 0–19 (56.3%)10 (52.6%)
 2–37 (43.8%)9 (47.4%)
MMSE score, average18.1 (±9.1)23.6 (±5.7)0.054
Extent of resection0.404
 Biopsy8 (50%)7 (36.8%)
 STR5 (31.6%)6 (31.6%)
 NTR2 (12.5%)6 (31.6%)
 GTR1 (6.3%)0
Resectable0.506
 Yes8 (50%)12 (63.2%)
 No8 (50%)7 (36.8%)
Tumor Extension0.018
 Unifocal4 (25%)13 (68.4%)
 Multifocal12 (75%)6 (31.6%)
Laterality of tumor0.379
 Unilateral12 (75%)29 (89.5%)
 Bilateral4 (25%)2 (10.5%)
MGMTa0.695
 Methylated8 (57.1%)6 (42.9%)
 Non-methylated5 (41.7%)7 (58.3%)
IDH mutationa1
 Yes1 (11.1%)3 (21.4%)
 No8 (88.9%)11 (78.6%)
CharacteristicsIntervention (n = 16)Control (n = 19)P-value
Age, average56.6 y (±19)52.4 y (±14.9)0.344
Sex
 Male11 (68.8%)13 (68.4%)
 Female5 (31.2%)6 (31.6%)
ECOG1.000
 0–19 (56.3%)10 (52.6%)
 2–37 (43.8%)9 (47.4%)
MMSE score, average18.1 (±9.1)23.6 (±5.7)0.054
Extent of resection0.404
 Biopsy8 (50%)7 (36.8%)
 STR5 (31.6%)6 (31.6%)
 NTR2 (12.5%)6 (31.6%)
 GTR1 (6.3%)0
Resectable0.506
 Yes8 (50%)12 (63.2%)
 No8 (50%)7 (36.8%)
Tumor Extension0.018
 Unifocal4 (25%)13 (68.4%)
 Multifocal12 (75%)6 (31.6%)
Laterality of tumor0.379
 Unilateral12 (75%)29 (89.5%)
 Bilateral4 (25%)2 (10.5%)
MGMTa0.695
 Methylated8 (57.1%)6 (42.9%)
 Non-methylated5 (41.7%)7 (58.3%)
IDH mutationa1
 Yes1 (11.1%)3 (21.4%)
 No8 (88.9%)11 (78.6%)

Abbreviations: ECOG, Eastern Cooperative Oncology Group; GTR, gross tumor resection; IDH, isocitrate dehydrogenase; MGMT, O6-Methylguanine-DNA Methyltransferase; MMSE, Mini-Mental State Examination; NTR, near-total resection; STR, sub-total resection.

aOut of available cases with molecular testing.

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