Changes in office BP and ABP at baseline and after 12-week dapagliflozin therapy (n = 83).
| . | Baseline (mean ± SD) . | Week 12 (mean ± SD) . | Absolute change (95% CI) . | P . |
|---|---|---|---|---|
| Office SBP (mmHg) | 139.5 ± 17.5 | 131.7 ± 12.9 | −7.9 (−12.1/−3.6) | <.001 |
| Office DBP (mmHg) | 80.7 ± 13.6 | 76.2 ± 7.5 | −4.4 (−7.6/−1.3) | .006 |
| 24-h SBP (mmHg) | 128.7 ± 12.4 | 126.4 ± 11.0 | −2.3 (−4.5/−0.2) | .032 |
| 24-h DBP (mmHg) | 73.2 ± 9.1 | 72.1 ± 7.5 | −1.1 (−2.7/0.5) | .169 |
| Daytime SBP (mmHg) | 131.6 ± 13.2 | 129.1 ± 11.0 | −2.4 (−4.8/−0.1) | .046 |
| Daytime DBP (mmHg) | 75.7 ± 9.0 | 74.0 ± 7.9 | −1.7 (−3.3/−0.1) | .046 |
| Nighttime SBP (mmHg) | 123.1 ± 13.6 | 120.1 ± 13.3 | −3.0 (−5.2/−0.8) | .010 |
| Nighttime DBP (mmHg) | 67.2 ± 11.1 | 66.1 ± 8.4 | −1.1 (−2.9/0.6) | .197 |
| Dipping status (%) | 31.3 | 50.6 | +19.3 | .005 |
| . | Baseline (mean ± SD) . | Week 12 (mean ± SD) . | Absolute change (95% CI) . | P . |
|---|---|---|---|---|
| Office SBP (mmHg) | 139.5 ± 17.5 | 131.7 ± 12.9 | −7.9 (−12.1/−3.6) | <.001 |
| Office DBP (mmHg) | 80.7 ± 13.6 | 76.2 ± 7.5 | −4.4 (−7.6/−1.3) | .006 |
| 24-h SBP (mmHg) | 128.7 ± 12.4 | 126.4 ± 11.0 | −2.3 (−4.5/−0.2) | .032 |
| 24-h DBP (mmHg) | 73.2 ± 9.1 | 72.1 ± 7.5 | −1.1 (−2.7/0.5) | .169 |
| Daytime SBP (mmHg) | 131.6 ± 13.2 | 129.1 ± 11.0 | −2.4 (−4.8/−0.1) | .046 |
| Daytime DBP (mmHg) | 75.7 ± 9.0 | 74.0 ± 7.9 | −1.7 (−3.3/−0.1) | .046 |
| Nighttime SBP (mmHg) | 123.1 ± 13.6 | 120.1 ± 13.3 | −3.0 (−5.2/−0.8) | .010 |
| Nighttime DBP (mmHg) | 67.2 ± 11.1 | 66.1 ± 8.4 | −1.1 (−2.9/0.6) | .197 |
| Dipping status (%) | 31.3 | 50.6 | +19.3 | .005 |
SD, standard deviation; DBP, diastolic blood pressure; CI, confidence interval.
Changes in office BP and ABP at baseline and after 12-week dapagliflozin therapy (n = 83).
| . | Baseline (mean ± SD) . | Week 12 (mean ± SD) . | Absolute change (95% CI) . | P . |
|---|---|---|---|---|
| Office SBP (mmHg) | 139.5 ± 17.5 | 131.7 ± 12.9 | −7.9 (−12.1/−3.6) | <.001 |
| Office DBP (mmHg) | 80.7 ± 13.6 | 76.2 ± 7.5 | −4.4 (−7.6/−1.3) | .006 |
| 24-h SBP (mmHg) | 128.7 ± 12.4 | 126.4 ± 11.0 | −2.3 (−4.5/−0.2) | .032 |
| 24-h DBP (mmHg) | 73.2 ± 9.1 | 72.1 ± 7.5 | −1.1 (−2.7/0.5) | .169 |
| Daytime SBP (mmHg) | 131.6 ± 13.2 | 129.1 ± 11.0 | −2.4 (−4.8/−0.1) | .046 |
| Daytime DBP (mmHg) | 75.7 ± 9.0 | 74.0 ± 7.9 | −1.7 (−3.3/−0.1) | .046 |
| Nighttime SBP (mmHg) | 123.1 ± 13.6 | 120.1 ± 13.3 | −3.0 (−5.2/−0.8) | .010 |
| Nighttime DBP (mmHg) | 67.2 ± 11.1 | 66.1 ± 8.4 | −1.1 (−2.9/0.6) | .197 |
| Dipping status (%) | 31.3 | 50.6 | +19.3 | .005 |
| . | Baseline (mean ± SD) . | Week 12 (mean ± SD) . | Absolute change (95% CI) . | P . |
|---|---|---|---|---|
| Office SBP (mmHg) | 139.5 ± 17.5 | 131.7 ± 12.9 | −7.9 (−12.1/−3.6) | <.001 |
| Office DBP (mmHg) | 80.7 ± 13.6 | 76.2 ± 7.5 | −4.4 (−7.6/−1.3) | .006 |
| 24-h SBP (mmHg) | 128.7 ± 12.4 | 126.4 ± 11.0 | −2.3 (−4.5/−0.2) | .032 |
| 24-h DBP (mmHg) | 73.2 ± 9.1 | 72.1 ± 7.5 | −1.1 (−2.7/0.5) | .169 |
| Daytime SBP (mmHg) | 131.6 ± 13.2 | 129.1 ± 11.0 | −2.4 (−4.8/−0.1) | .046 |
| Daytime DBP (mmHg) | 75.7 ± 9.0 | 74.0 ± 7.9 | −1.7 (−3.3/−0.1) | .046 |
| Nighttime SBP (mmHg) | 123.1 ± 13.6 | 120.1 ± 13.3 | −3.0 (−5.2/−0.8) | .010 |
| Nighttime DBP (mmHg) | 67.2 ± 11.1 | 66.1 ± 8.4 | −1.1 (−2.9/0.6) | .197 |
| Dipping status (%) | 31.3 | 50.6 | +19.3 | .005 |
SD, standard deviation; DBP, diastolic blood pressure; CI, confidence interval.
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