Table 2.

Comparison between DeepPCT and existing methods on testing set.

MethodAUCAUPRMCCF1
DeepPCTsite0.6840.1300.1290.171
DeepPCTsiteAF30.7540.1730.1750.193
DeepPCTgraph0.7220.1060.1270.169
DeepPCTgraphAF30.7350.1860.1750.194
DeepPCTstr0.7540.1270.1560.197
DeepPCTstrAF30.7650.2450.2200.242
DeepPCTseq0.7330.2380.2090.167
DeepPCT0.7620.2400.2100.235
DeepPCTAF30.7770.2780.2450.258
PCTseq0.6640.1820.1230.168
PCTstr0.6760.1370.1320.172
PCTstrAF30.6550.1250.1520.191
PCTpred0.6800.1650.1540.195
PCTpred AF30.6780.1510.1610.202
PTM-Xseq0.6880.1660.2330.252
PTM-Xstr0.5430.0750.1060.151
PTM-Xstr AF30.5280.1120.1050.151
PTM-X0.6670.1520.1220.166
PTM-X AF30.6710.1560.1260.167
MethodAUCAUPRMCCF1
DeepPCTsite0.6840.1300.1290.171
DeepPCTsiteAF30.7540.1730.1750.193
DeepPCTgraph0.7220.1060.1270.169
DeepPCTgraphAF30.7350.1860.1750.194
DeepPCTstr0.7540.1270.1560.197
DeepPCTstrAF30.7650.2450.2200.242
DeepPCTseq0.7330.2380.2090.167
DeepPCT0.7620.2400.2100.235
DeepPCTAF30.7770.2780.2450.258
PCTseq0.6640.1820.1230.168
PCTstr0.6760.1370.1320.172
PCTstrAF30.6550.1250.1520.191
PCTpred0.6800.1650.1540.195
PCTpred AF30.6780.1510.1610.202
PTM-Xseq0.6880.1660.2330.252
PTM-Xstr0.5430.0750.1060.151
PTM-Xstr AF30.5280.1120.1050.151
PTM-X0.6670.1520.1220.166
PTM-X AF30.6710.1560.1260.167

AF3 denotes that AlphaFold3-based predicted structures were used.

PCTseq and PCTstr are the sequence and structure-based predictors of PCTpred, respectively.

PTM-Xseq and PTM-Xstr denote only using sequence and structural features of PTM-X, respectively.

Table 2.

Comparison between DeepPCT and existing methods on testing set.

MethodAUCAUPRMCCF1
DeepPCTsite0.6840.1300.1290.171
DeepPCTsiteAF30.7540.1730.1750.193
DeepPCTgraph0.7220.1060.1270.169
DeepPCTgraphAF30.7350.1860.1750.194
DeepPCTstr0.7540.1270.1560.197
DeepPCTstrAF30.7650.2450.2200.242
DeepPCTseq0.7330.2380.2090.167
DeepPCT0.7620.2400.2100.235
DeepPCTAF30.7770.2780.2450.258
PCTseq0.6640.1820.1230.168
PCTstr0.6760.1370.1320.172
PCTstrAF30.6550.1250.1520.191
PCTpred0.6800.1650.1540.195
PCTpred AF30.6780.1510.1610.202
PTM-Xseq0.6880.1660.2330.252
PTM-Xstr0.5430.0750.1060.151
PTM-Xstr AF30.5280.1120.1050.151
PTM-X0.6670.1520.1220.166
PTM-X AF30.6710.1560.1260.167
MethodAUCAUPRMCCF1
DeepPCTsite0.6840.1300.1290.171
DeepPCTsiteAF30.7540.1730.1750.193
DeepPCTgraph0.7220.1060.1270.169
DeepPCTgraphAF30.7350.1860.1750.194
DeepPCTstr0.7540.1270.1560.197
DeepPCTstrAF30.7650.2450.2200.242
DeepPCTseq0.7330.2380.2090.167
DeepPCT0.7620.2400.2100.235
DeepPCTAF30.7770.2780.2450.258
PCTseq0.6640.1820.1230.168
PCTstr0.6760.1370.1320.172
PCTstrAF30.6550.1250.1520.191
PCTpred0.6800.1650.1540.195
PCTpred AF30.6780.1510.1610.202
PTM-Xseq0.6880.1660.2330.252
PTM-Xstr0.5430.0750.1060.151
PTM-Xstr AF30.5280.1120.1050.151
PTM-X0.6670.1520.1220.166
PTM-X AF30.6710.1560.1260.167

AF3 denotes that AlphaFold3-based predicted structures were used.

PCTseq and PCTstr are the sequence and structure-based predictors of PCTpred, respectively.

PTM-Xseq and PTM-Xstr denote only using sequence and structural features of PTM-X, respectively.

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