Table 3

Criteria and diagnostic accuracy of tests for predicting segmental recovery of dysfunction after revascularization

Method (ref)CriteriaSensitivity (95% CI)Specificity (95% CI)DOR (95% CI)PPV (95% CI)NPV (95% CI)
LDD-TTE71Improvement of WMS > 181 (80–82)80 (79–81)24.53 (24.32–24.74)77 (76–78)85 (84–86)
SPECT
 201-Tl71Preserved resting perfusion or redistribution86 (84–88)59 (56–62)8.79 (8.60–8.98)69 (67–71)80 (77–83)
 99Tc tracers71Preserved resting perfusion81 (78–84)66 (63–69)5.40 (8.60–8.98)71 (68–74)77 (74–80)
 FDG PET71Preserved FDG in sector with reduced perfusion93 (91–95)58 (54–62)18.16 (17.85–18.46)71 (68–74)86 (83–89)
CMR
 LGE92<25% transmurality95 (93–97)51 (40–62)21.12 (10.98–40.55)69 (56–80)90 (85–93)
 LDD92Improvement of WMS > 181 (73–86)91 (84–95)41.57 (18.25–94.68)93 (87–97)75 (65–83)
Method (ref)CriteriaSensitivity (95% CI)Specificity (95% CI)DOR (95% CI)PPV (95% CI)NPV (95% CI)
LDD-TTE71Improvement of WMS > 181 (80–82)80 (79–81)24.53 (24.32–24.74)77 (76–78)85 (84–86)
SPECT
 201-Tl71Preserved resting perfusion or redistribution86 (84–88)59 (56–62)8.79 (8.60–8.98)69 (67–71)80 (77–83)
 99Tc tracers71Preserved resting perfusion81 (78–84)66 (63–69)5.40 (8.60–8.98)71 (68–74)77 (74–80)
 FDG PET71Preserved FDG in sector with reduced perfusion93 (91–95)58 (54–62)18.16 (17.85–18.46)71 (68–74)86 (83–89)
CMR
 LGE92<25% transmurality95 (93–97)51 (40–62)21.12 (10.98–40.55)69 (56–80)90 (85–93)
 LDD92Improvement of WMS > 181 (73–86)91 (84–95)41.57 (18.25–94.68)93 (87–97)75 (65–83)

CMR, cardiovascular magnetic resonance; FDG, fluorodeoxyglucose; LDD, low-dose dobutamine; LGE, late-gadolinium enhancement; PET, positron emission tomography; SPECT, single photon emission computed tomography.

Table 3

Criteria and diagnostic accuracy of tests for predicting segmental recovery of dysfunction after revascularization

Method (ref)CriteriaSensitivity (95% CI)Specificity (95% CI)DOR (95% CI)PPV (95% CI)NPV (95% CI)
LDD-TTE71Improvement of WMS > 181 (80–82)80 (79–81)24.53 (24.32–24.74)77 (76–78)85 (84–86)
SPECT
 201-Tl71Preserved resting perfusion or redistribution86 (84–88)59 (56–62)8.79 (8.60–8.98)69 (67–71)80 (77–83)
 99Tc tracers71Preserved resting perfusion81 (78–84)66 (63–69)5.40 (8.60–8.98)71 (68–74)77 (74–80)
 FDG PET71Preserved FDG in sector with reduced perfusion93 (91–95)58 (54–62)18.16 (17.85–18.46)71 (68–74)86 (83–89)
CMR
 LGE92<25% transmurality95 (93–97)51 (40–62)21.12 (10.98–40.55)69 (56–80)90 (85–93)
 LDD92Improvement of WMS > 181 (73–86)91 (84–95)41.57 (18.25–94.68)93 (87–97)75 (65–83)
Method (ref)CriteriaSensitivity (95% CI)Specificity (95% CI)DOR (95% CI)PPV (95% CI)NPV (95% CI)
LDD-TTE71Improvement of WMS > 181 (80–82)80 (79–81)24.53 (24.32–24.74)77 (76–78)85 (84–86)
SPECT
 201-Tl71Preserved resting perfusion or redistribution86 (84–88)59 (56–62)8.79 (8.60–8.98)69 (67–71)80 (77–83)
 99Tc tracers71Preserved resting perfusion81 (78–84)66 (63–69)5.40 (8.60–8.98)71 (68–74)77 (74–80)
 FDG PET71Preserved FDG in sector with reduced perfusion93 (91–95)58 (54–62)18.16 (17.85–18.46)71 (68–74)86 (83–89)
CMR
 LGE92<25% transmurality95 (93–97)51 (40–62)21.12 (10.98–40.55)69 (56–80)90 (85–93)
 LDD92Improvement of WMS > 181 (73–86)91 (84–95)41.57 (18.25–94.68)93 (87–97)75 (65–83)

CMR, cardiovascular magnetic resonance; FDG, fluorodeoxyglucose; LDD, low-dose dobutamine; LGE, late-gadolinium enhancement; PET, positron emission tomography; SPECT, single photon emission computed tomography.

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