IC10 and IC50 values (μM) of compounds competing with FITC-T4 for binding to TTR.
. | IC10 . | 95% CI of IC10 . | IC50 . | 95% CI of IC50 . |
---|---|---|---|---|
T4 | 2.4×10−3 | 1.8×10−3 to 3.3×10−3 | 5.2×10−2 | 4.6×10−2 to 5.9×10−2 |
Bitertanol | 0.22 | 0.07 to 0.66 | 62.7 | 36.1 to 137 |
Difenoconazole | 0.23 | 0.12 to 0.43 | 38.5 | 28.6 to 54.2 |
4-methylbenzotriazole | 1.3 | 0.96 to 1.8 | 23.3 | 20.4 to 26.9 |
PFBS | 0.82 | 0.68 to 0.99 | 8.3 | 7.6 to 9.0 |
PFHxS | 3.4×10−2 | 2.8×10−2 to 4.2×10−2 | 0.27 | 0.25 to 0.29 |
PFOS | 4.7×10−2 | 4.1×10−2 to 5.3×10−2 | 0.21 | 0.20 to 0.22 |
PFHxA | 0.20 | 0.13 to 0.32 | 2.6 | 2.1 to 3.2 |
PFOA | 5.3×10−2 | 4.6×10−2 to 6.1×10−2 | 0.28 | 0.27 to 0.30 |
GenX | 1.9 | 1.3 to 2.9 | 31.9 | 26.8 to 38.4 |
. | IC10 . | 95% CI of IC10 . | IC50 . | 95% CI of IC50 . |
---|---|---|---|---|
T4 | 2.4×10−3 | 1.8×10−3 to 3.3×10−3 | 5.2×10−2 | 4.6×10−2 to 5.9×10−2 |
Bitertanol | 0.22 | 0.07 to 0.66 | 62.7 | 36.1 to 137 |
Difenoconazole | 0.23 | 0.12 to 0.43 | 38.5 | 28.6 to 54.2 |
4-methylbenzotriazole | 1.3 | 0.96 to 1.8 | 23.3 | 20.4 to 26.9 |
PFBS | 0.82 | 0.68 to 0.99 | 8.3 | 7.6 to 9.0 |
PFHxS | 3.4×10−2 | 2.8×10−2 to 4.2×10−2 | 0.27 | 0.25 to 0.29 |
PFOS | 4.7×10−2 | 4.1×10−2 to 5.3×10−2 | 0.21 | 0.20 to 0.22 |
PFHxA | 0.20 | 0.13 to 0.32 | 2.6 | 2.1 to 3.2 |
PFOA | 5.3×10−2 | 4.6×10−2 to 6.1×10−2 | 0.28 | 0.27 to 0.30 |
GenX | 1.9 | 1.3 to 2.9 | 31.9 | 26.8 to 38.4 |
IC10 and IC50 values (μM) of compounds competing with FITC-T4 for binding to TTR.
. | IC10 . | 95% CI of IC10 . | IC50 . | 95% CI of IC50 . |
---|---|---|---|---|
T4 | 2.4×10−3 | 1.8×10−3 to 3.3×10−3 | 5.2×10−2 | 4.6×10−2 to 5.9×10−2 |
Bitertanol | 0.22 | 0.07 to 0.66 | 62.7 | 36.1 to 137 |
Difenoconazole | 0.23 | 0.12 to 0.43 | 38.5 | 28.6 to 54.2 |
4-methylbenzotriazole | 1.3 | 0.96 to 1.8 | 23.3 | 20.4 to 26.9 |
PFBS | 0.82 | 0.68 to 0.99 | 8.3 | 7.6 to 9.0 |
PFHxS | 3.4×10−2 | 2.8×10−2 to 4.2×10−2 | 0.27 | 0.25 to 0.29 |
PFOS | 4.7×10−2 | 4.1×10−2 to 5.3×10−2 | 0.21 | 0.20 to 0.22 |
PFHxA | 0.20 | 0.13 to 0.32 | 2.6 | 2.1 to 3.2 |
PFOA | 5.3×10−2 | 4.6×10−2 to 6.1×10−2 | 0.28 | 0.27 to 0.30 |
GenX | 1.9 | 1.3 to 2.9 | 31.9 | 26.8 to 38.4 |
. | IC10 . | 95% CI of IC10 . | IC50 . | 95% CI of IC50 . |
---|---|---|---|---|
T4 | 2.4×10−3 | 1.8×10−3 to 3.3×10−3 | 5.2×10−2 | 4.6×10−2 to 5.9×10−2 |
Bitertanol | 0.22 | 0.07 to 0.66 | 62.7 | 36.1 to 137 |
Difenoconazole | 0.23 | 0.12 to 0.43 | 38.5 | 28.6 to 54.2 |
4-methylbenzotriazole | 1.3 | 0.96 to 1.8 | 23.3 | 20.4 to 26.9 |
PFBS | 0.82 | 0.68 to 0.99 | 8.3 | 7.6 to 9.0 |
PFHxS | 3.4×10−2 | 2.8×10−2 to 4.2×10−2 | 0.27 | 0.25 to 0.29 |
PFOS | 4.7×10−2 | 4.1×10−2 to 5.3×10−2 | 0.21 | 0.20 to 0.22 |
PFHxA | 0.20 | 0.13 to 0.32 | 2.6 | 2.1 to 3.2 |
PFOA | 5.3×10−2 | 4.6×10−2 to 6.1×10−2 | 0.28 | 0.27 to 0.30 |
GenX | 1.9 | 1.3 to 2.9 | 31.9 | 26.8 to 38.4 |
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