Table 3.
Open in new tab

EC10/IC10 values and EC50/IC50 values (μM) of compounds showing agonism or antagonism toward the ER.

ER agonism
ER antagonism
EC1095% CI of EC10EC5095% CI of EC50IC1095% CI of IC10IC5095% CI of IC50
E27.4 × 10−74.9 × 10−7, 1.1 × 10−63.7 × 10−62.9 × 10−6, 4.5 × 10−6
ICI-182.7806.0 × 10−64.9 × 10−6 to 7.4 × 10−62.8 × 10−52.5 × 10−5 to 3.0 × 10−5
Ametryn30.924.8 to 38.210899.5 to 119
Bitertanol0.530.2 to 1.39.36.2 to 14.7
Fenbuconazole6.95.5 to 8.624.021.9 to 26.4
Tebuconazole16.612.1 to 23.245.437.8 to 54.8
Cyproconazole26.411.6 to 46.9227140 to 650
Difenoconazole0.550.33 to 0.942.21.7 to 2.8
Propiconazole9.66.0 to 15.536.028.5 to 45.7
Paclobutrazol13.68.5 to 21.284.568.7 to 109
Triadimenol3.40.65 to 12.612856.8 to 880
ER agonism
ER antagonism
EC1095% CI of EC10EC5095% CI of EC50IC1095% CI of IC10IC5095% CI of IC50
E27.4 × 10−74.9 × 10−7, 1.1 × 10−63.7 × 10−62.9 × 10−6, 4.5 × 10−6
ICI-182.7806.0 × 10−64.9 × 10−6 to 7.4 × 10−62.8 × 10−52.5 × 10−5 to 3.0 × 10−5
Ametryn30.924.8 to 38.210899.5 to 119
Bitertanol0.530.2 to 1.39.36.2 to 14.7
Fenbuconazole6.95.5 to 8.624.021.9 to 26.4
Tebuconazole16.612.1 to 23.245.437.8 to 54.8
Cyproconazole26.411.6 to 46.9227140 to 650
Difenoconazole0.550.33 to 0.942.21.7 to 2.8
Propiconazole9.66.0 to 15.536.028.5 to 45.7
Paclobutrazol13.68.5 to 21.284.568.7 to 109
Triadimenol3.40.65 to 12.612856.8 to 880
Table 3.
Open in new tab

EC10/IC10 values and EC50/IC50 values (μM) of compounds showing agonism or antagonism toward the ER.

ER agonism
ER antagonism
EC1095% CI of EC10EC5095% CI of EC50IC1095% CI of IC10IC5095% CI of IC50
E27.4 × 10−74.9 × 10−7, 1.1 × 10−63.7 × 10−62.9 × 10−6, 4.5 × 10−6
ICI-182.7806.0 × 10−64.9 × 10−6 to 7.4 × 10−62.8 × 10−52.5 × 10−5 to 3.0 × 10−5
Ametryn30.924.8 to 38.210899.5 to 119
Bitertanol0.530.2 to 1.39.36.2 to 14.7
Fenbuconazole6.95.5 to 8.624.021.9 to 26.4
Tebuconazole16.612.1 to 23.245.437.8 to 54.8
Cyproconazole26.411.6 to 46.9227140 to 650
Difenoconazole0.550.33 to 0.942.21.7 to 2.8
Propiconazole9.66.0 to 15.536.028.5 to 45.7
Paclobutrazol13.68.5 to 21.284.568.7 to 109
Triadimenol3.40.65 to 12.612856.8 to 880
ER agonism
ER antagonism
EC1095% CI of EC10EC5095% CI of EC50IC1095% CI of IC10IC5095% CI of IC50
E27.4 × 10−74.9 × 10−7, 1.1 × 10−63.7 × 10−62.9 × 10−6, 4.5 × 10−6
ICI-182.7806.0 × 10−64.9 × 10−6 to 7.4 × 10−62.8 × 10−52.5 × 10−5 to 3.0 × 10−5
Ametryn30.924.8 to 38.210899.5 to 119
Bitertanol0.530.2 to 1.39.36.2 to 14.7
Fenbuconazole6.95.5 to 8.624.021.9 to 26.4
Tebuconazole16.612.1 to 23.245.437.8 to 54.8
Cyproconazole26.411.6 to 46.9227140 to 650
Difenoconazole0.550.33 to 0.942.21.7 to 2.8
Propiconazole9.66.0 to 15.536.028.5 to 45.7
Paclobutrazol13.68.5 to 21.284.568.7 to 109
Triadimenol3.40.65 to 12.612856.8 to 880
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