. | No response . | Weak response . | Strong response . |
---|---|---|---|
Receptor activity assays | No response | EC10 or IC10 > 5 μM | EC10 or IC10 < 5 μM |
TTR binding | No response | EC10 or IC10 > 100 nM | EC10 or IC10 < 100 nM |
H295R | No response | ECIR1.5 > 2 μM | ECIR1.5 < 2 μM |
. | No response . | Weak response . | Strong response . |
---|---|---|---|
Receptor activity assays | No response | EC10 or IC10 > 5 μM | EC10 or IC10 < 5 μM |
TTR binding | No response | EC10 or IC10 > 100 nM | EC10 or IC10 < 100 nM |
H295R | No response | ECIR1.5 > 2 μM | ECIR1.5 < 2 μM |
. | No response . | Weak response . | Strong response . |
---|---|---|---|
Receptor activity assays | No response | EC10 or IC10 > 5 μM | EC10 or IC10 < 5 μM |
TTR binding | No response | EC10 or IC10 > 100 nM | EC10 or IC10 < 100 nM |
H295R | No response | ECIR1.5 > 2 μM | ECIR1.5 < 2 μM |
. | No response . | Weak response . | Strong response . |
---|---|---|---|
Receptor activity assays | No response | EC10 or IC10 > 5 μM | EC10 or IC10 < 5 μM |
TTR binding | No response | EC10 or IC10 > 100 nM | EC10 or IC10 < 100 nM |
H295R | No response | ECIR1.5 > 2 μM | ECIR1.5 < 2 μM |
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