| Characteristics Mean, (SD) Unless Indicated) . | HIV-negative VL, N = 14 . | HIV-positive VL, N = 7 . | Healthy Controls, N = 5 . | HIV Controls, N = 5 . |
|---|---|---|---|---|
| Age (y) | 24.50 (6.09) | 37.29 (5.38) | 30.60 (12.90) | 41.00 (12.12) |
| Body mass index | 17.43 (2.21) | 15.61 (2.55) | 19.38 (3.27) | 20.44 (1.96) |
| Male sex (n, %) | 13 (92.86%) | 7 (100.00%) | 4 (80.00%) | 5 (100%) |
| Hemoglobin (g/dL) | 8.64 (2.42) | 8.73 (1.14) | ND | ND |
| Duration of illness (d) | 71.46 (55.25) | 63.00 (37.99) | N/A | N/A |
| Spleen size (cm below CM) | 8.64 (5.72) | 13.14 (5.01) | N/A | N/A |
| Liver size (cm below CM) | 4.00 (1.27) | 6.50 (2.12) | N/A | N/A |
| Parasite load (median, IQR) | 1.00 (1.00) | 6.00 (1.00) | N/A | N/A |
| Platelet count | 57 290 (25 130) | 101 570 (16 630) | ND | ND |
| T, NK, and NKT cell percentages in peripheral blood (mean %, ±SD) | ||||
| CD3 T cells | 7.68 (5.92) | 3.26 (1.76) | 3.76 (2.26) | 5.07 (3.70) |
| CD4 T cells | 5.03 (4.01) | 1.11 (0.87) | 2.22 (1.04) | 1.65 (1.24) |
| CD8 T cells | 1.42 (1.80) | 1.65 (1.07) | 0.53 (0.23) | N/D |
| NK cells | 0.91 (0.87) | 0.86 (0.54) | 1.10 (0.90) | 0.97 (0.71) |
| NKT cells | 0.25 (0.28) | 0.22 (0.12) | 0.23 (0.24) | 0.31 (0.33) |
| Clinical outcomesa (n, %) | ||||
| Died | 3 (21.43%) | 1 (14.29%) | N/A | N/A |
| Survived | 11 (78.57%) | 5 (71.43%) | N/A | N/A |
| Characteristics Mean, (SD) Unless Indicated) . | HIV-negative VL, N = 14 . | HIV-positive VL, N = 7 . | Healthy Controls, N = 5 . | HIV Controls, N = 5 . |
|---|---|---|---|---|
| Age (y) | 24.50 (6.09) | 37.29 (5.38) | 30.60 (12.90) | 41.00 (12.12) |
| Body mass index | 17.43 (2.21) | 15.61 (2.55) | 19.38 (3.27) | 20.44 (1.96) |
| Male sex (n, %) | 13 (92.86%) | 7 (100.00%) | 4 (80.00%) | 5 (100%) |
| Hemoglobin (g/dL) | 8.64 (2.42) | 8.73 (1.14) | ND | ND |
| Duration of illness (d) | 71.46 (55.25) | 63.00 (37.99) | N/A | N/A |
| Spleen size (cm below CM) | 8.64 (5.72) | 13.14 (5.01) | N/A | N/A |
| Liver size (cm below CM) | 4.00 (1.27) | 6.50 (2.12) | N/A | N/A |
| Parasite load (median, IQR) | 1.00 (1.00) | 6.00 (1.00) | N/A | N/A |
| Platelet count | 57 290 (25 130) | 101 570 (16 630) | ND | ND |
| T, NK, and NKT cell percentages in peripheral blood (mean %, ±SD) | ||||
| CD3 T cells | 7.68 (5.92) | 3.26 (1.76) | 3.76 (2.26) | 5.07 (3.70) |
| CD4 T cells | 5.03 (4.01) | 1.11 (0.87) | 2.22 (1.04) | 1.65 (1.24) |
| CD8 T cells | 1.42 (1.80) | 1.65 (1.07) | 0.53 (0.23) | N/D |
| NK cells | 0.91 (0.87) | 0.86 (0.54) | 1.10 (0.90) | 0.97 (0.71) |
| NKT cells | 0.25 (0.28) | 0.22 (0.12) | 0.23 (0.24) | 0.31 (0.33) |
| Clinical outcomesa (n, %) | ||||
| Died | 3 (21.43%) | 1 (14.29%) | N/A | N/A |
| Survived | 11 (78.57%) | 5 (71.43%) | N/A | N/A |
Abbreviations: CM, costal margin; IQR, interquartile range; N/A, not applicable; N/D, not done; NK, natural killer; VL, viral load.
aThe clinical outcome of 1 VL-HIV patient who defaulted is unknown.
| Characteristics Mean, (SD) Unless Indicated) . | HIV-negative VL, N = 14 . | HIV-positive VL, N = 7 . | Healthy Controls, N = 5 . | HIV Controls, N = 5 . |
|---|---|---|---|---|
| Age (y) | 24.50 (6.09) | 37.29 (5.38) | 30.60 (12.90) | 41.00 (12.12) |
| Body mass index | 17.43 (2.21) | 15.61 (2.55) | 19.38 (3.27) | 20.44 (1.96) |
| Male sex (n, %) | 13 (92.86%) | 7 (100.00%) | 4 (80.00%) | 5 (100%) |
| Hemoglobin (g/dL) | 8.64 (2.42) | 8.73 (1.14) | ND | ND |
| Duration of illness (d) | 71.46 (55.25) | 63.00 (37.99) | N/A | N/A |
| Spleen size (cm below CM) | 8.64 (5.72) | 13.14 (5.01) | N/A | N/A |
| Liver size (cm below CM) | 4.00 (1.27) | 6.50 (2.12) | N/A | N/A |
| Parasite load (median, IQR) | 1.00 (1.00) | 6.00 (1.00) | N/A | N/A |
| Platelet count | 57 290 (25 130) | 101 570 (16 630) | ND | ND |
| T, NK, and NKT cell percentages in peripheral blood (mean %, ±SD) | ||||
| CD3 T cells | 7.68 (5.92) | 3.26 (1.76) | 3.76 (2.26) | 5.07 (3.70) |
| CD4 T cells | 5.03 (4.01) | 1.11 (0.87) | 2.22 (1.04) | 1.65 (1.24) |
| CD8 T cells | 1.42 (1.80) | 1.65 (1.07) | 0.53 (0.23) | N/D |
| NK cells | 0.91 (0.87) | 0.86 (0.54) | 1.10 (0.90) | 0.97 (0.71) |
| NKT cells | 0.25 (0.28) | 0.22 (0.12) | 0.23 (0.24) | 0.31 (0.33) |
| Clinical outcomesa (n, %) | ||||
| Died | 3 (21.43%) | 1 (14.29%) | N/A | N/A |
| Survived | 11 (78.57%) | 5 (71.43%) | N/A | N/A |
| Characteristics Mean, (SD) Unless Indicated) . | HIV-negative VL, N = 14 . | HIV-positive VL, N = 7 . | Healthy Controls, N = 5 . | HIV Controls, N = 5 . |
|---|---|---|---|---|
| Age (y) | 24.50 (6.09) | 37.29 (5.38) | 30.60 (12.90) | 41.00 (12.12) |
| Body mass index | 17.43 (2.21) | 15.61 (2.55) | 19.38 (3.27) | 20.44 (1.96) |
| Male sex (n, %) | 13 (92.86%) | 7 (100.00%) | 4 (80.00%) | 5 (100%) |
| Hemoglobin (g/dL) | 8.64 (2.42) | 8.73 (1.14) | ND | ND |
| Duration of illness (d) | 71.46 (55.25) | 63.00 (37.99) | N/A | N/A |
| Spleen size (cm below CM) | 8.64 (5.72) | 13.14 (5.01) | N/A | N/A |
| Liver size (cm below CM) | 4.00 (1.27) | 6.50 (2.12) | N/A | N/A |
| Parasite load (median, IQR) | 1.00 (1.00) | 6.00 (1.00) | N/A | N/A |
| Platelet count | 57 290 (25 130) | 101 570 (16 630) | ND | ND |
| T, NK, and NKT cell percentages in peripheral blood (mean %, ±SD) | ||||
| CD3 T cells | 7.68 (5.92) | 3.26 (1.76) | 3.76 (2.26) | 5.07 (3.70) |
| CD4 T cells | 5.03 (4.01) | 1.11 (0.87) | 2.22 (1.04) | 1.65 (1.24) |
| CD8 T cells | 1.42 (1.80) | 1.65 (1.07) | 0.53 (0.23) | N/D |
| NK cells | 0.91 (0.87) | 0.86 (0.54) | 1.10 (0.90) | 0.97 (0.71) |
| NKT cells | 0.25 (0.28) | 0.22 (0.12) | 0.23 (0.24) | 0.31 (0.33) |
| Clinical outcomesa (n, %) | ||||
| Died | 3 (21.43%) | 1 (14.29%) | N/A | N/A |
| Survived | 11 (78.57%) | 5 (71.43%) | N/A | N/A |
Abbreviations: CM, costal margin; IQR, interquartile range; N/A, not applicable; N/D, not done; NK, natural killer; VL, viral load.
aThe clinical outcome of 1 VL-HIV patient who defaulted is unknown.
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