Table 3. Open in new tab Univariable and...

Category

Univariable

Multivariable

95% CI

P^a

95% CI

P value^a

Year

0.001

<.001

Per unit

1.47

1.18, 1.85

1.56

1.22, 2.01

Journal quantile ranking

0.28

Q1 (top 25%)

Reference

Q2–Q4

0.70

0.37, 1.34

Continent

0.01^a

.10^a

America

Reference

Europe

6.31

1.42, 28.17

4.99

1.03, 24.02

Asia/Other

3.14

0.71, 13.80

3.09

0.68, 14.13

No. of authors

0.63^a

1–3

Reference

4–5

1.42

0.69, 2.93

≥6

1.18

0.54, 2.59

Design

0.36^a

Parallel

Reference

Split mouth

0.86

0.40, 1.82

Cross over

2.31

0.67, 8.03

Methodologist

0.50

Reference

Yes

0.71

0.26, 1.92

Center

0.84

Single

Reference

Multi

1.09

0.48, 2.50

Type of outcome

0.02

.02

Efficacy

Reference

Safety

0.39

0.18, 0.86

0.38

0.17, 0.88

Statistical significance

0.61

Reference

Yes

0.86

0.48, 1.54

Funding

<0.001^a

.02^a

None/No information

Reference

Industry/Company

4.85

1.99, 11.82

2.76

0.98, 7.77

University/State

2.58

1.31, 5.08

2.82

1.39, 5.74

Both

4.90

1.47, 16.32

3.13

0.82, 12.00

Registration

0.02

Reference

Yes

2.20

1.15, 4.22

Table 3.

Open in new tab

Univariable and multivariable logistic regression with odds ratios and respective confidence intervals for the effect of year, journal quantile ranking, continent (geographical affiliation), no. of authors, design, no. of centres, type of outcome, funding, and registration on data sharing statement (n = 318).

Category	Univariable			Multivariable
	OR	95% CI	P^a	OR	95% CI	P value^a
Year			0.001			<.001
Per unit	1.47	1.18, 1.85		1.56	1.22, 2.01
Journal quantile ranking			0.28
Q1 (top 25%)	Reference
Q2–Q4	0.70	0.37, 1.34
Continent			0.01^a			.10^a
America	Reference			Reference
Europe	6.31	1.42, 28.17		4.99	1.03, 24.02
Asia/Other	3.14	0.71, 13.80		3.09	0.68, 14.13
No. of authors			0.63^a
1–3	Reference
4–5	1.42	0.69, 2.93
≥6	1.18	0.54, 2.59
Design			0.36^a
Parallel	Reference
Split mouth	0.86	0.40, 1.82
Cross over	2.31	0.67, 8.03
Methodologist			0.50
No	Reference
Yes	0.71	0.26, 1.92
Center			0.84
Single	Reference
Multi	1.09	0.48, 2.50
Type of outcome			0.02			.02
Efficacy	Reference			Reference
Safety	0.39	0.18, 0.86		0.38	0.17, 0.88
Statistical significance			0.61
No	Reference
Yes	0.86	0.48, 1.54
Funding			<0.001^a			.02^a
None/No information	Reference			Reference
Industry/Company	4.85	1.99, 11.82		2.76	0.98, 7.77
University/State	2.58	1.31, 5.08		2.82	1.39, 5.74
Both	4.90	1.47, 16.32		3.13	0.82, 12.00
Registration			0.02
No	Reference
Yes	2.20	1.15, 4.22

Category	Univariable			Multivariable
	OR	95% CI	P^a	OR	95% CI	P value^a
Year			0.001			<.001
Per unit	1.47	1.18, 1.85		1.56	1.22, 2.01
Journal quantile ranking			0.28
Q1 (top 25%)	Reference
Q2–Q4	0.70	0.37, 1.34
Continent			0.01^a			.10^a
America	Reference			Reference
Europe	6.31	1.42, 28.17		4.99	1.03, 24.02
Asia/Other	3.14	0.71, 13.80		3.09	0.68, 14.13
No. of authors			0.63^a
1–3	Reference
4–5	1.42	0.69, 2.93
≥6	1.18	0.54, 2.59
Design			0.36^a
Parallel	Reference
Split mouth	0.86	0.40, 1.82
Cross over	2.31	0.67, 8.03
Methodologist			0.50
No	Reference
Yes	0.71	0.26, 1.92
Center			0.84
Single	Reference
Multi	1.09	0.48, 2.50
Type of outcome			0.02			.02
Efficacy	Reference			Reference
Safety	0.39	0.18, 0.86		0.38	0.17, 0.88
Statistical significance			0.61
No	Reference
Yes	0.86	0.48, 1.54
Funding			<0.001^a			.02^a
None/No information	Reference			Reference
Industry/Company	4.85	1.99, 11.82		2.76	0.98, 7.77
University/State	2.58	1.31, 5.08		2.82	1.39, 5.74
Both	4.90	1.47, 16.32		3.13	0.82, 12.00
Registration			0.02
No	Reference
Yes	2.20	1.15, 4.22

^aWald test for overall statistical significance.

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