Table 2.
Open in new tab

ROC AUC results comparing the original PRS and the modified PRSs.a

CausesOutcomePRSoutcomeModified PRS
Hypertension, CHD, myocardial infarctionHeart failure0.5800.678
Hypertension, CHDMyocardial infarction0.6590.779
CHDAngina pectoris0.6550.784
CausesOutcomePRSoutcomeModified PRS
Hypertension, CHD, myocardial infarctionHeart failure0.5800.678
Hypertension, CHDMyocardial infarction0.6590.779
CHDAngina pectoris0.6550.784
a

Modified PRS refers to the PRS fitted using the outcome PRS and PRSs of the causes via logistic regression.

Table 2.
Open in new tab

ROC AUC results comparing the original PRS and the modified PRSs.a

CausesOutcomePRSoutcomeModified PRS
Hypertension, CHD, myocardial infarctionHeart failure0.5800.678
Hypertension, CHDMyocardial infarction0.6590.779
CHDAngina pectoris0.6550.784
CausesOutcomePRSoutcomeModified PRS
Hypertension, CHD, myocardial infarctionHeart failure0.5800.678
Hypertension, CHDMyocardial infarction0.6590.779
CHDAngina pectoris0.6550.784
a

Modified PRS refers to the PRS fitted using the outcome PRS and PRSs of the causes via logistic regression.

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