Multinomial Logistic Regression Analysis of Ischemic Heart Disease (IHD) in the MARK-AGE Population
| Variables . | Categories . | IHD . | p Value . |
|---|---|---|---|
| OR (95% CI) . | |||
| Age | 1.0 (0.97–1.05) | NS | |
| Sex | Males | 3.45 (1.81–6.59) | <.0001 |
| Females | 1 (reference) | ||
| Countries | 0.91 (0.80–1.03) | NS | |
| BMI | 1.01 (0.96–1.08) | NS | |
| Cu/Zn | 3.71 (1.63–8.42) | .002 | |
| CMV-IgG | 1.00 (0.99–1.01) | NS | |
| CRP | 1.00 (0.94–1.07) | NS | |
| TTV viremia | <4 log | 1 (reference) | |
| ≥4 log | 2.51 (1.42–4.43) | .002 | |
| Diabetes | Yes | 2.54 (1.22–5.26) | .012 |
| No | 1 (reference) | ||
| Hypertension | Yes | 2.34 (1.37–3.99) | .002 |
| No | 1 (reference) | ||
| Hypercholesterolemia | Yes | 0.68 (0.39–1.16) | NS |
| No | 1 (reference) | ||
| Smoking | Current | 2.08 (1.13–3.84) | .019 |
| No | 1 (reference) |
| Variables . | Categories . | IHD . | p Value . |
|---|---|---|---|
| OR (95% CI) . | |||
| Age | 1.0 (0.97–1.05) | NS | |
| Sex | Males | 3.45 (1.81–6.59) | <.0001 |
| Females | 1 (reference) | ||
| Countries | 0.91 (0.80–1.03) | NS | |
| BMI | 1.01 (0.96–1.08) | NS | |
| Cu/Zn | 3.71 (1.63–8.42) | .002 | |
| CMV-IgG | 1.00 (0.99–1.01) | NS | |
| CRP | 1.00 (0.94–1.07) | NS | |
| TTV viremia | <4 log | 1 (reference) | |
| ≥4 log | 2.51 (1.42–4.43) | .002 | |
| Diabetes | Yes | 2.54 (1.22–5.26) | .012 |
| No | 1 (reference) | ||
| Hypertension | Yes | 2.34 (1.37–3.99) | .002 |
| No | 1 (reference) | ||
| Hypercholesterolemia | Yes | 0.68 (0.39–1.16) | NS |
| No | 1 (reference) | ||
| Smoking | Current | 2.08 (1.13–3.84) | .019 |
| No | 1 (reference) |
Notes: Gender was categorized as follows: 1 = males and 0 = females. BMI = body mass index; CI = confidence interval; CMV-IgG = cytomegalovirus IgG; CRP = C-reactive protein; Cu/Zn = copper/zinc ratio; IgG = immunoglobulin G; NS = not significant; OR = odds ratio; TTV = Torquetenovirus.
Multinomial Logistic Regression Analysis of Ischemic Heart Disease (IHD) in the MARK-AGE Population
| Variables . | Categories . | IHD . | p Value . |
|---|---|---|---|
| OR (95% CI) . | |||
| Age | 1.0 (0.97–1.05) | NS | |
| Sex | Males | 3.45 (1.81–6.59) | <.0001 |
| Females | 1 (reference) | ||
| Countries | 0.91 (0.80–1.03) | NS | |
| BMI | 1.01 (0.96–1.08) | NS | |
| Cu/Zn | 3.71 (1.63–8.42) | .002 | |
| CMV-IgG | 1.00 (0.99–1.01) | NS | |
| CRP | 1.00 (0.94–1.07) | NS | |
| TTV viremia | <4 log | 1 (reference) | |
| ≥4 log | 2.51 (1.42–4.43) | .002 | |
| Diabetes | Yes | 2.54 (1.22–5.26) | .012 |
| No | 1 (reference) | ||
| Hypertension | Yes | 2.34 (1.37–3.99) | .002 |
| No | 1 (reference) | ||
| Hypercholesterolemia | Yes | 0.68 (0.39–1.16) | NS |
| No | 1 (reference) | ||
| Smoking | Current | 2.08 (1.13–3.84) | .019 |
| No | 1 (reference) |
| Variables . | Categories . | IHD . | p Value . |
|---|---|---|---|
| OR (95% CI) . | |||
| Age | 1.0 (0.97–1.05) | NS | |
| Sex | Males | 3.45 (1.81–6.59) | <.0001 |
| Females | 1 (reference) | ||
| Countries | 0.91 (0.80–1.03) | NS | |
| BMI | 1.01 (0.96–1.08) | NS | |
| Cu/Zn | 3.71 (1.63–8.42) | .002 | |
| CMV-IgG | 1.00 (0.99–1.01) | NS | |
| CRP | 1.00 (0.94–1.07) | NS | |
| TTV viremia | <4 log | 1 (reference) | |
| ≥4 log | 2.51 (1.42–4.43) | .002 | |
| Diabetes | Yes | 2.54 (1.22–5.26) | .012 |
| No | 1 (reference) | ||
| Hypertension | Yes | 2.34 (1.37–3.99) | .002 |
| No | 1 (reference) | ||
| Hypercholesterolemia | Yes | 0.68 (0.39–1.16) | NS |
| No | 1 (reference) | ||
| Smoking | Current | 2.08 (1.13–3.84) | .019 |
| No | 1 (reference) |
Notes: Gender was categorized as follows: 1 = males and 0 = females. BMI = body mass index; CI = confidence interval; CMV-IgG = cytomegalovirus IgG; CRP = C-reactive protein; Cu/Zn = copper/zinc ratio; IgG = immunoglobulin G; NS = not significant; OR = odds ratio; TTV = Torquetenovirus.
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