Associations between hair cortisol and cortisone concentrations and first-trimester growth.
| Mixed models (n = 107) . | Model 1 . | Model 2 . | ||||
|---|---|---|---|---|---|---|
| β . | 95% CI . | P-value . | β . | 95% CI . | P-value . | |
| Crown–rump length (√mm) | ||||||
| Cortisol (pg/mg) | –0.003 | –0.016 to 0.010 | 0.620 | –0.007 | –0.019 to 0.006 | 0.312 |
| Cortisone (pg/mg) | 0.001 | –0.004 to 0.008 | 0.555 | 0.001 | –0.005 to 0.007 | 0.820 |
| Embryonic volume (3√cm3) | ||||||
| Cortisol (pg/mg) | –0.008 | –0.016 to 0.000 | 0.057 | –0.010 | –0.017 to –0.002 | 0.011 |
| Cortisone (pg/mg) | 0.001 | –0.003 to 0.004 | 0.767 | 0.000 | –0.004 to 0.004 | 0.964 |
| Mixed models (n = 107) . | Model 1 . | Model 2 . | ||||
|---|---|---|---|---|---|---|
| β . | 95% CI . | P-value . | β . | 95% CI . | P-value . | |
| Crown–rump length (√mm) | ||||||
| Cortisol (pg/mg) | –0.003 | –0.016 to 0.010 | 0.620 | –0.007 | –0.019 to 0.006 | 0.312 |
| Cortisone (pg/mg) | 0.001 | –0.004 to 0.008 | 0.555 | 0.001 | –0.005 to 0.007 | 0.820 |
| Embryonic volume (3√cm3) | ||||||
| Cortisol (pg/mg) | –0.008 | –0.016 to 0.000 | 0.057 | –0.010 | –0.017 to –0.002 | 0.011 |
| Cortisone (pg/mg) | 0.001 | –0.003 to 0.004 | 0.767 | 0.000 | –0.004 to 0.004 | 0.964 |
Model 1 was adjusted for gestational age at the 3D ultrasound scan visit. Model 2 was additionally adjusted for corticosteroid use within the last 3 months, natural hair color, age, BMI, smoking, vegetable intake, and fetal sex. Values are presented in bold where P ≤ 0.05.
Associations between hair cortisol and cortisone concentrations and first-trimester growth.
| Mixed models (n = 107) . | Model 1 . | Model 2 . | ||||
|---|---|---|---|---|---|---|
| β . | 95% CI . | P-value . | β . | 95% CI . | P-value . | |
| Crown–rump length (√mm) | ||||||
| Cortisol (pg/mg) | –0.003 | –0.016 to 0.010 | 0.620 | –0.007 | –0.019 to 0.006 | 0.312 |
| Cortisone (pg/mg) | 0.001 | –0.004 to 0.008 | 0.555 | 0.001 | –0.005 to 0.007 | 0.820 |
| Embryonic volume (3√cm3) | ||||||
| Cortisol (pg/mg) | –0.008 | –0.016 to 0.000 | 0.057 | –0.010 | –0.017 to –0.002 | 0.011 |
| Cortisone (pg/mg) | 0.001 | –0.003 to 0.004 | 0.767 | 0.000 | –0.004 to 0.004 | 0.964 |
| Mixed models (n = 107) . | Model 1 . | Model 2 . | ||||
|---|---|---|---|---|---|---|
| β . | 95% CI . | P-value . | β . | 95% CI . | P-value . | |
| Crown–rump length (√mm) | ||||||
| Cortisol (pg/mg) | –0.003 | –0.016 to 0.010 | 0.620 | –0.007 | –0.019 to 0.006 | 0.312 |
| Cortisone (pg/mg) | 0.001 | –0.004 to 0.008 | 0.555 | 0.001 | –0.005 to 0.007 | 0.820 |
| Embryonic volume (3√cm3) | ||||||
| Cortisol (pg/mg) | –0.008 | –0.016 to 0.000 | 0.057 | –0.010 | –0.017 to –0.002 | 0.011 |
| Cortisone (pg/mg) | 0.001 | –0.003 to 0.004 | 0.767 | 0.000 | –0.004 to 0.004 | 0.964 |
Model 1 was adjusted for gestational age at the 3D ultrasound scan visit. Model 2 was additionally adjusted for corticosteroid use within the last 3 months, natural hair color, age, BMI, smoking, vegetable intake, and fetal sex. Values are presented in bold where P ≤ 0.05.
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