Table 3.

Univariate and multivariate analysis of factors for overall survival (OS)

CharacteristicAHR95% CIUnivariate PAHR95% CIMultivariate P
Age
<55 y1<.00011
≥55 y2.5761.997-3.3231.6441.268-2.133<.0001
Sex
Male1
Female1.1410.861-1.510.359
Histopathology
PTC11
FTC2.0491.570-2.675<.00010.7530.595-1.068.091
HTC3.2231.750-5.9341.3950.753-2.587
Surgery
Total thyroidectomy1
Less than total thyroidectomy1.1720.907-1.515.224
Metastases
Lung only11
Bone only4.8523.257-7.229<.00012.4851.590-3.882<.0001
Multiple organs5.5313.657-8.3652.5261.618-3.943
Groups
A11
B2.3711.662-3.384<.0011.1500.795-1.665.059
C2.5581.826-3.5840.8160.567-1.174
Radiotherapy
No1
Yes1.2150.932-1.582.150
Last 131I WBS
Negative11
Positive12.0987.381-19.831<.00018.9075.249-15.112<.0001
CharacteristicAHR95% CIUnivariate PAHR95% CIMultivariate P
Age
<55 y1<.00011
≥55 y2.5761.997-3.3231.6441.268-2.133<.0001
Sex
Male1
Female1.1410.861-1.510.359
Histopathology
PTC11
FTC2.0491.570-2.675<.00010.7530.595-1.068.091
HTC3.2231.750-5.9341.3950.753-2.587
Surgery
Total thyroidectomy1
Less than total thyroidectomy1.1720.907-1.515.224
Metastases
Lung only11
Bone only4.8523.257-7.229<.00012.4851.590-3.882<.0001
Multiple organs5.5313.657-8.3652.5261.618-3.943
Groups
A11
B2.3711.662-3.384<.0011.1500.795-1.665.059
C2.5581.826-3.5840.8160.567-1.174
Radiotherapy
No1
Yes1.2150.932-1.582.150
Last 131I WBS
Negative11
Positive12.0987.381-19.831<.00018.9075.249-15.112<.0001

Only those variables with P < .05 in univariate analysis were included in the multivariable analysis. Total numbers are highlighted as bold.

Abbreviations: AHR, adjusted hazard ratio; FTC, follicular thyroid cancer; HTC, Hurtle cell thyroid cancer; PTC, papillary thyroid cancer; WBS, whole body scan.

Table 3.

Univariate and multivariate analysis of factors for overall survival (OS)

CharacteristicAHR95% CIUnivariate PAHR95% CIMultivariate P
Age
<55 y1<.00011
≥55 y2.5761.997-3.3231.6441.268-2.133<.0001
Sex
Male1
Female1.1410.861-1.510.359
Histopathology
PTC11
FTC2.0491.570-2.675<.00010.7530.595-1.068.091
HTC3.2231.750-5.9341.3950.753-2.587
Surgery
Total thyroidectomy1
Less than total thyroidectomy1.1720.907-1.515.224
Metastases
Lung only11
Bone only4.8523.257-7.229<.00012.4851.590-3.882<.0001
Multiple organs5.5313.657-8.3652.5261.618-3.943
Groups
A11
B2.3711.662-3.384<.0011.1500.795-1.665.059
C2.5581.826-3.5840.8160.567-1.174
Radiotherapy
No1
Yes1.2150.932-1.582.150
Last 131I WBS
Negative11
Positive12.0987.381-19.831<.00018.9075.249-15.112<.0001
CharacteristicAHR95% CIUnivariate PAHR95% CIMultivariate P
Age
<55 y1<.00011
≥55 y2.5761.997-3.3231.6441.268-2.133<.0001
Sex
Male1
Female1.1410.861-1.510.359
Histopathology
PTC11
FTC2.0491.570-2.675<.00010.7530.595-1.068.091
HTC3.2231.750-5.9341.3950.753-2.587
Surgery
Total thyroidectomy1
Less than total thyroidectomy1.1720.907-1.515.224
Metastases
Lung only11
Bone only4.8523.257-7.229<.00012.4851.590-3.882<.0001
Multiple organs5.5313.657-8.3652.5261.618-3.943
Groups
A11
B2.3711.662-3.384<.0011.1500.795-1.665.059
C2.5581.826-3.5840.8160.567-1.174
Radiotherapy
No1
Yes1.2150.932-1.582.150
Last 131I WBS
Negative11
Positive12.0987.381-19.831<.00018.9075.249-15.112<.0001

Only those variables with P < .05 in univariate analysis were included in the multivariable analysis. Total numbers are highlighted as bold.

Abbreviations: AHR, adjusted hazard ratio; FTC, follicular thyroid cancer; HTC, Hurtle cell thyroid cancer; PTC, papillary thyroid cancer; WBS, whole body scan.

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