Comparison of characteristics of UC patients with and without any type of vascular lesion
| . | At least 1 vascular lesion . | No vascular lesions . | Univariate analysis . | Multivariate analysis . | ||
|---|---|---|---|---|---|---|
| OR (95% CI) . | P . | OR (95% CI) . | P . | |||
| Age, y | 42.37 ± 7.65 | 35.27 ± 8.1 | 1.1 (1.03-1.16) | .0006 | 1.1 (0.99-1.25 | .06 |
| Male | 58.3 (14/24) | 50 (18/36) | 1.4 (0.48-4.01) | .52 | ||
| Body mass index, kg/m2 | 24.82 ± 3.32 | 23.2 ± 3.48 | 1.16 (0.99-1.34) | .06 | ||
| Extensive colitis | 58.3 (14/24) | 33.3 (12/36) | 2.81 (1.01-8.5) | .05 | 3.64 (0.72-18.27) | .1 |
| Disease duration, y | 13.12 ± 7.92 | 6.3 ± 5.76 | 1.13 (1.05-1.21) | .0001 | 1.13 (1.01-1.37) | .05 |
| Mucosal healing | 41.6 (10/24) | 63.8 (23/36) | 0.4 (0.14-1.16) | .1 | ||
| UC medication use | ||||||
| Mesalamine | 83.3 (20/24) | 66.67 (24/36) | 2.5 (0.67-9.27) | .15 | ||
| Thiopurines | 37.5 (9/24) | 22.2 (8/36) | 2.1 (0.65-6.74) | .19 | ||
| Systemic steroids | 8.3 (2/24) | 16.67 (6/36) | 0.45 (0.08-2.53) | .35 | ||
| Biologics | 33.3 (8/24) | 16.67 (6/36) | 1.67 (0.35-7.92) | .31 | ||
| Dyslipidemia | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Hypertension | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Total cholesterol, mg/dL | 212.1 ± 35.23 | 209.87 ± 30.48 | 1.03 (0.97-1.23) | .1 | ||
| HDL Cholesterol, mg/dL | 54.75 ± 14.51 | 60 ± 17.39 | 0.98 (0.94-1.01) | .14 | ||
| LDL cholesterol, mg/dL | 131 ± 13.03 | 118.1 ± 27.84 | 1.02 (0.97-1.05) | .09 | ||
| Triglycerides, mg/dL | 95.5 ± 44.84 | 105.72 ± 44.64 | 0.99 (0.97-1) | .18 | ||
| C-reactive protein, mg/L | 6.8 ± 6.6 | 3.2 ± 2.9 | 3.66 (1.29-10.39) | .01 | 25.13 (1.6-394.38) | .01 |
| . | At least 1 vascular lesion . | No vascular lesions . | Univariate analysis . | Multivariate analysis . | ||
|---|---|---|---|---|---|---|
| OR (95% CI) . | P . | OR (95% CI) . | P . | |||
| Age, y | 42.37 ± 7.65 | 35.27 ± 8.1 | 1.1 (1.03-1.16) | .0006 | 1.1 (0.99-1.25 | .06 |
| Male | 58.3 (14/24) | 50 (18/36) | 1.4 (0.48-4.01) | .52 | ||
| Body mass index, kg/m2 | 24.82 ± 3.32 | 23.2 ± 3.48 | 1.16 (0.99-1.34) | .06 | ||
| Extensive colitis | 58.3 (14/24) | 33.3 (12/36) | 2.81 (1.01-8.5) | .05 | 3.64 (0.72-18.27) | .1 |
| Disease duration, y | 13.12 ± 7.92 | 6.3 ± 5.76 | 1.13 (1.05-1.21) | .0001 | 1.13 (1.01-1.37) | .05 |
| Mucosal healing | 41.6 (10/24) | 63.8 (23/36) | 0.4 (0.14-1.16) | .1 | ||
| UC medication use | ||||||
| Mesalamine | 83.3 (20/24) | 66.67 (24/36) | 2.5 (0.67-9.27) | .15 | ||
| Thiopurines | 37.5 (9/24) | 22.2 (8/36) | 2.1 (0.65-6.74) | .19 | ||
| Systemic steroids | 8.3 (2/24) | 16.67 (6/36) | 0.45 (0.08-2.53) | .35 | ||
| Biologics | 33.3 (8/24) | 16.67 (6/36) | 1.67 (0.35-7.92) | .31 | ||
| Dyslipidemia | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Hypertension | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Total cholesterol, mg/dL | 212.1 ± 35.23 | 209.87 ± 30.48 | 1.03 (0.97-1.23) | .1 | ||
| HDL Cholesterol, mg/dL | 54.75 ± 14.51 | 60 ± 17.39 | 0.98 (0.94-1.01) | .14 | ||
| LDL cholesterol, mg/dL | 131 ± 13.03 | 118.1 ± 27.84 | 1.02 (0.97-1.05) | .09 | ||
| Triglycerides, mg/dL | 95.5 ± 44.84 | 105.72 ± 44.64 | 0.99 (0.97-1) | .18 | ||
| C-reactive protein, mg/L | 6.8 ± 6.6 | 3.2 ± 2.9 | 3.66 (1.29-10.39) | .01 | 25.13 (1.6-394.38) | .01 |
Values are mean ± SD or % (n/n).
Abbreviations: CI, confidence interval; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OR, odds ratio; UC, ulcerative colitis.
Comparison of characteristics of UC patients with and without any type of vascular lesion
| . | At least 1 vascular lesion . | No vascular lesions . | Univariate analysis . | Multivariate analysis . | ||
|---|---|---|---|---|---|---|
| OR (95% CI) . | P . | OR (95% CI) . | P . | |||
| Age, y | 42.37 ± 7.65 | 35.27 ± 8.1 | 1.1 (1.03-1.16) | .0006 | 1.1 (0.99-1.25 | .06 |
| Male | 58.3 (14/24) | 50 (18/36) | 1.4 (0.48-4.01) | .52 | ||
| Body mass index, kg/m2 | 24.82 ± 3.32 | 23.2 ± 3.48 | 1.16 (0.99-1.34) | .06 | ||
| Extensive colitis | 58.3 (14/24) | 33.3 (12/36) | 2.81 (1.01-8.5) | .05 | 3.64 (0.72-18.27) | .1 |
| Disease duration, y | 13.12 ± 7.92 | 6.3 ± 5.76 | 1.13 (1.05-1.21) | .0001 | 1.13 (1.01-1.37) | .05 |
| Mucosal healing | 41.6 (10/24) | 63.8 (23/36) | 0.4 (0.14-1.16) | .1 | ||
| UC medication use | ||||||
| Mesalamine | 83.3 (20/24) | 66.67 (24/36) | 2.5 (0.67-9.27) | .15 | ||
| Thiopurines | 37.5 (9/24) | 22.2 (8/36) | 2.1 (0.65-6.74) | .19 | ||
| Systemic steroids | 8.3 (2/24) | 16.67 (6/36) | 0.45 (0.08-2.53) | .35 | ||
| Biologics | 33.3 (8/24) | 16.67 (6/36) | 1.67 (0.35-7.92) | .31 | ||
| Dyslipidemia | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Hypertension | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Total cholesterol, mg/dL | 212.1 ± 35.23 | 209.87 ± 30.48 | 1.03 (0.97-1.23) | .1 | ||
| HDL Cholesterol, mg/dL | 54.75 ± 14.51 | 60 ± 17.39 | 0.98 (0.94-1.01) | .14 | ||
| LDL cholesterol, mg/dL | 131 ± 13.03 | 118.1 ± 27.84 | 1.02 (0.97-1.05) | .09 | ||
| Triglycerides, mg/dL | 95.5 ± 44.84 | 105.72 ± 44.64 | 0.99 (0.97-1) | .18 | ||
| C-reactive protein, mg/L | 6.8 ± 6.6 | 3.2 ± 2.9 | 3.66 (1.29-10.39) | .01 | 25.13 (1.6-394.38) | .01 |
| . | At least 1 vascular lesion . | No vascular lesions . | Univariate analysis . | Multivariate analysis . | ||
|---|---|---|---|---|---|---|
| OR (95% CI) . | P . | OR (95% CI) . | P . | |||
| Age, y | 42.37 ± 7.65 | 35.27 ± 8.1 | 1.1 (1.03-1.16) | .0006 | 1.1 (0.99-1.25 | .06 |
| Male | 58.3 (14/24) | 50 (18/36) | 1.4 (0.48-4.01) | .52 | ||
| Body mass index, kg/m2 | 24.82 ± 3.32 | 23.2 ± 3.48 | 1.16 (0.99-1.34) | .06 | ||
| Extensive colitis | 58.3 (14/24) | 33.3 (12/36) | 2.81 (1.01-8.5) | .05 | 3.64 (0.72-18.27) | .1 |
| Disease duration, y | 13.12 ± 7.92 | 6.3 ± 5.76 | 1.13 (1.05-1.21) | .0001 | 1.13 (1.01-1.37) | .05 |
| Mucosal healing | 41.6 (10/24) | 63.8 (23/36) | 0.4 (0.14-1.16) | .1 | ||
| UC medication use | ||||||
| Mesalamine | 83.3 (20/24) | 66.67 (24/36) | 2.5 (0.67-9.27) | .15 | ||
| Thiopurines | 37.5 (9/24) | 22.2 (8/36) | 2.1 (0.65-6.74) | .19 | ||
| Systemic steroids | 8.3 (2/24) | 16.67 (6/36) | 0.45 (0.08-2.53) | .35 | ||
| Biologics | 33.3 (8/24) | 16.67 (6/36) | 1.67 (0.35-7.92) | .31 | ||
| Dyslipidemia | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Hypertension | 8.3 (2/24) | 5.56 (2/36) | 1.54 (0.19-12.03) | .67 | ||
| Total cholesterol, mg/dL | 212.1 ± 35.23 | 209.87 ± 30.48 | 1.03 (0.97-1.23) | .1 | ||
| HDL Cholesterol, mg/dL | 54.75 ± 14.51 | 60 ± 17.39 | 0.98 (0.94-1.01) | .14 | ||
| LDL cholesterol, mg/dL | 131 ± 13.03 | 118.1 ± 27.84 | 1.02 (0.97-1.05) | .09 | ||
| Triglycerides, mg/dL | 95.5 ± 44.84 | 105.72 ± 44.64 | 0.99 (0.97-1) | .18 | ||
| C-reactive protein, mg/L | 6.8 ± 6.6 | 3.2 ± 2.9 | 3.66 (1.29-10.39) | .01 | 25.13 (1.6-394.38) | .01 |
Values are mean ± SD or % (n/n).
Abbreviations: CI, confidence interval; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OR, odds ratio; UC, ulcerative colitis.
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