Table 3.

Multivariable Logistic Regression Model for Diagnosed PASC (n = 41 160)

CharacteristicTotal With PASC, No. (%)aOR95% CIP Value
Age, per 10 y1.171.14–1.19<.001
 0–17110 (1.6)
 18–39730 (5.2)
 40–64984 (7.4)
 ≥651033 (15.0)
Sex
 Male1100 (6.0)
 Female1757 (7.7)1.511.38–1.64<.001
Race
 White2639 (7.1)
 Asian67 (5.4)1.07.81–1.39.6
 Black99 (6.0)1.07.85–1.33.5
 Other52 (5.5)1.01.74–1.36>.9
COVID-19 variant era
 Ancestral351 (8.1)
 Alpha78 (7.4)0.90.67–1.18.5
 Delta1179 (7.2)0.97.84–1.12.7
 Omicron1249 (6.5)0.67.58–.78<.001
Hospitalization for COVID-19
 No1567 (4.1)
 Hospitalized, no ICU909 (37.4)10.19.06–11.2<.001
 Hospitalized, ICU381 (40.3)11.09.43–12.8<.001
 CCI, severity weighted, per increase of 11.051.03–1.07<.001
 01337 (4.5)
 ≥11520 (13.6)
Vaccination status at time of SARS-CoV-2 infection
 Unvaccinated1654 (6.9)
 2 mRNA doses584 (6.1)0.98.87–1.09.7
 >2 mRNA doses619 (8.2)1.10.97–1.24.14
CharacteristicTotal With PASC, No. (%)aOR95% CIP Value
Age, per 10 y1.171.14–1.19<.001
 0–17110 (1.6)
 18–39730 (5.2)
 40–64984 (7.4)
 ≥651033 (15.0)
Sex
 Male1100 (6.0)
 Female1757 (7.7)1.511.38–1.64<.001
Race
 White2639 (7.1)
 Asian67 (5.4)1.07.81–1.39.6
 Black99 (6.0)1.07.85–1.33.5
 Other52 (5.5)1.01.74–1.36>.9
COVID-19 variant era
 Ancestral351 (8.1)
 Alpha78 (7.4)0.90.67–1.18.5
 Delta1179 (7.2)0.97.84–1.12.7
 Omicron1249 (6.5)0.67.58–.78<.001
Hospitalization for COVID-19
 No1567 (4.1)
 Hospitalized, no ICU909 (37.4)10.19.06–11.2<.001
 Hospitalized, ICU381 (40.3)11.09.43–12.8<.001
 CCI, severity weighted, per increase of 11.051.03–1.07<.001
 01337 (4.5)
 ≥11520 (13.6)
Vaccination status at time of SARS-CoV-2 infection
 Unvaccinated1654 (6.9)
 2 mRNA doses584 (6.1)0.98.87–1.09.7
 >2 mRNA doses619 (8.2)1.10.97–1.24.14

Multivariable model included only the terms shown. Interaction terms with vaccination status and the main effect of smoking were not included in this model for presentation purposes. PASC was diagnosed between 30 days and 6 months after infection.

Abbreviations: aOR, adjusted odds ratio; CCI, Charlson Comorbidity Index; ICU, intensive care unit; PASC, postacute sequelae of COVID-19.

Table 3.

Multivariable Logistic Regression Model for Diagnosed PASC (n = 41 160)

CharacteristicTotal With PASC, No. (%)aOR95% CIP Value
Age, per 10 y1.171.14–1.19<.001
 0–17110 (1.6)
 18–39730 (5.2)
 40–64984 (7.4)
 ≥651033 (15.0)
Sex
 Male1100 (6.0)
 Female1757 (7.7)1.511.38–1.64<.001
Race
 White2639 (7.1)
 Asian67 (5.4)1.07.81–1.39.6
 Black99 (6.0)1.07.85–1.33.5
 Other52 (5.5)1.01.74–1.36>.9
COVID-19 variant era
 Ancestral351 (8.1)
 Alpha78 (7.4)0.90.67–1.18.5
 Delta1179 (7.2)0.97.84–1.12.7
 Omicron1249 (6.5)0.67.58–.78<.001
Hospitalization for COVID-19
 No1567 (4.1)
 Hospitalized, no ICU909 (37.4)10.19.06–11.2<.001
 Hospitalized, ICU381 (40.3)11.09.43–12.8<.001
 CCI, severity weighted, per increase of 11.051.03–1.07<.001
 01337 (4.5)
 ≥11520 (13.6)
Vaccination status at time of SARS-CoV-2 infection
 Unvaccinated1654 (6.9)
 2 mRNA doses584 (6.1)0.98.87–1.09.7
 >2 mRNA doses619 (8.2)1.10.97–1.24.14
CharacteristicTotal With PASC, No. (%)aOR95% CIP Value
Age, per 10 y1.171.14–1.19<.001
 0–17110 (1.6)
 18–39730 (5.2)
 40–64984 (7.4)
 ≥651033 (15.0)
Sex
 Male1100 (6.0)
 Female1757 (7.7)1.511.38–1.64<.001
Race
 White2639 (7.1)
 Asian67 (5.4)1.07.81–1.39.6
 Black99 (6.0)1.07.85–1.33.5
 Other52 (5.5)1.01.74–1.36>.9
COVID-19 variant era
 Ancestral351 (8.1)
 Alpha78 (7.4)0.90.67–1.18.5
 Delta1179 (7.2)0.97.84–1.12.7
 Omicron1249 (6.5)0.67.58–.78<.001
Hospitalization for COVID-19
 No1567 (4.1)
 Hospitalized, no ICU909 (37.4)10.19.06–11.2<.001
 Hospitalized, ICU381 (40.3)11.09.43–12.8<.001
 CCI, severity weighted, per increase of 11.051.03–1.07<.001
 01337 (4.5)
 ≥11520 (13.6)
Vaccination status at time of SARS-CoV-2 infection
 Unvaccinated1654 (6.9)
 2 mRNA doses584 (6.1)0.98.87–1.09.7
 >2 mRNA doses619 (8.2)1.10.97–1.24.14

Multivariable model included only the terms shown. Interaction terms with vaccination status and the main effect of smoking were not included in this model for presentation purposes. PASC was diagnosed between 30 days and 6 months after infection.

Abbreviations: aOR, adjusted odds ratio; CCI, Charlson Comorbidity Index; ICU, intensive care unit; PASC, postacute sequelae of COVID-19.

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