Table 4
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Poisson regression analysis for the association between FRAX risk factors and 10-year probability of major osteoporotic fracture.

Univariable analysisMultivariable analysis
10-Year probability
[95% CI]		p10-Year probability
[95% CI]		p
Age (per 1-year)1.03 [1.02, 1.04]<.0011.02 [1.01, 1.03].045
Weight (kg)0.96 [0.95, 0.99].0180.99 [0.97, 1.01].888
Height (cm)0.99 [0.98, 1.01].2690.99 [0.98, 1.01].863
Ever smoked1.18 [0.85, 1.65].5941.14 [0.58, 2.22].710
Current alcohol intake1.20 [0.90, 1.62].2241.14 [0.83, 1.57].427
HIV infection1.26 [1.14, 1.41].0071.03 [0.86, 1.25].703
FN T-score0.46 [0.44, 0.57]<.0010.86 [0.79, 0.94].001
Parental hip fracture2.18 [1.91, 2.46]<.0012.12 [1.66, 2.66]<.001
Prior fracture2.07 [1.82, 2.36]<.0011.79 [1.43, 2.22]<.001
Univariable analysisMultivariable analysis
10-Year probability
[95% CI]		p10-Year probability
[95% CI]		p
Age (per 1-year)1.03 [1.02, 1.04]<.0011.02 [1.01, 1.03].045
Weight (kg)0.96 [0.95, 0.99].0180.99 [0.97, 1.01].888
Height (cm)0.99 [0.98, 1.01].2690.99 [0.98, 1.01].863
Ever smoked1.18 [0.85, 1.65].5941.14 [0.58, 2.22].710
Current alcohol intake1.20 [0.90, 1.62].2241.14 [0.83, 1.57].427
HIV infection1.26 [1.14, 1.41].0071.03 [0.86, 1.25].703
FN T-score0.46 [0.44, 0.57]<.0010.86 [0.79, 0.94].001
Parental hip fracture2.18 [1.91, 2.46]<.0012.12 [1.66, 2.66]<.001
Prior fracture2.07 [1.82, 2.36]<.0011.79 [1.43, 2.22]<.001

The expected probabilities are presented as rate = eβ; with the β coefficients calculated from the Poisson models. BMD T-scores were calculated using the NHANES III reference values. FRAX calculation included HIV as a secondary cause for osteoporosis. The socioeconomic status (SES) coefficient represents the SD change in outcome for each quintile increase in SES.

Abbreviation: NHANES, National Health and Nutrition Examination Survey

Table 4
Open in new tab

Poisson regression analysis for the association between FRAX risk factors and 10-year probability of major osteoporotic fracture.

Univariable analysisMultivariable analysis
10-Year probability
[95% CI]		p10-Year probability
[95% CI]		p
Age (per 1-year)1.03 [1.02, 1.04]<.0011.02 [1.01, 1.03].045
Weight (kg)0.96 [0.95, 0.99].0180.99 [0.97, 1.01].888
Height (cm)0.99 [0.98, 1.01].2690.99 [0.98, 1.01].863
Ever smoked1.18 [0.85, 1.65].5941.14 [0.58, 2.22].710
Current alcohol intake1.20 [0.90, 1.62].2241.14 [0.83, 1.57].427
HIV infection1.26 [1.14, 1.41].0071.03 [0.86, 1.25].703
FN T-score0.46 [0.44, 0.57]<.0010.86 [0.79, 0.94].001
Parental hip fracture2.18 [1.91, 2.46]<.0012.12 [1.66, 2.66]<.001
Prior fracture2.07 [1.82, 2.36]<.0011.79 [1.43, 2.22]<.001
Univariable analysisMultivariable analysis
10-Year probability
[95% CI]		p10-Year probability
[95% CI]		p
Age (per 1-year)1.03 [1.02, 1.04]<.0011.02 [1.01, 1.03].045
Weight (kg)0.96 [0.95, 0.99].0180.99 [0.97, 1.01].888
Height (cm)0.99 [0.98, 1.01].2690.99 [0.98, 1.01].863
Ever smoked1.18 [0.85, 1.65].5941.14 [0.58, 2.22].710
Current alcohol intake1.20 [0.90, 1.62].2241.14 [0.83, 1.57].427
HIV infection1.26 [1.14, 1.41].0071.03 [0.86, 1.25].703
FN T-score0.46 [0.44, 0.57]<.0010.86 [0.79, 0.94].001
Parental hip fracture2.18 [1.91, 2.46]<.0012.12 [1.66, 2.66]<.001
Prior fracture2.07 [1.82, 2.36]<.0011.79 [1.43, 2.22]<.001

The expected probabilities are presented as rate = eβ; with the β coefficients calculated from the Poisson models. BMD T-scores were calculated using the NHANES III reference values. FRAX calculation included HIV as a secondary cause for osteoporosis. The socioeconomic status (SES) coefficient represents the SD change in outcome for each quintile increase in SES.

Abbreviation: NHANES, National Health and Nutrition Examination Survey

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