| Family . | Subfamily . | P. pacificus . | C. elegans . | p value . |
|---|---|---|---|---|
| HISTONE ACETYLTRANSFERASE | CBP/P300 | 12 | 7 | 0.170 |
| GNAT | 15 | 11 | ||
| MYST | 7 | 4 | ||
| Other | 2 | 1 | ||
| HISTONE DEACETYLASE | Class I | 4 | 3 | 1 |
| Class II | 4 | 5 | ||
| Class III | 5 | 4 | ||
| Class IV | 1 | 1 | ||
| HISTONE METHYLTRANSFERASE | PRMT | 12 | 3 | 0.052 |
| SET | 45 | 31 | ||
| DOT1 | 6 | 6 | ||
| Other | 1 | 1 | ||
| HISTONE DEMETHYLASE | JMJ | 20 | 12 | 0.399 |
| LSD | 2 | 3 | ||
| HISTONES | H1 | 5 | 9 | 0.004* |
| H2A | 13 | 19 | ||
| H2B | 12 | 17 | ||
| H3 | 19 | 24 | ||
| H4 | 12 | 16 | ||
| DNA METHYLATION | DNA methyltransferase | 1 | 0 | 1 |
| ALKB | 5 | 5 | ||
| DAMT-1 | 1 | 1 | ||
| NCRNA ASSOCIATED | Dicer | 1 | 1 | 0.609 |
| RdRP | 5 | 4 | ||
| Helicases | 7 | 4 | ||
| Argonautes | 23 | 20 | ||
| Drosha | 1 | 1 | ||
| Microprocessor complex | 2 | 1 | ||
| CHROMATIN REMODELERS | SWI/SNF | 2 | 2 | 1 |
| ISWI | 2 | 1 | ||
| INO80 | 1 | 1 | ||
| CHD | 3 | 4 | ||
| OTHERS | Histone kinase | 17 | 22 | 0.475 |
| Histone phosphatase | 5 | 6 | ||
| Histone ubiquitin transferase | 9 | 7 | ||
| Histone deubiquitinase | 6 | 6 | ||
| Misc. | 3 | 2 | ||
| TOTAL | 291 | 265 |
| Family . | Subfamily . | P. pacificus . | C. elegans . | p value . |
|---|---|---|---|---|
| HISTONE ACETYLTRANSFERASE | CBP/P300 | 12 | 7 | 0.170 |
| GNAT | 15 | 11 | ||
| MYST | 7 | 4 | ||
| Other | 2 | 1 | ||
| HISTONE DEACETYLASE | Class I | 4 | 3 | 1 |
| Class II | 4 | 5 | ||
| Class III | 5 | 4 | ||
| Class IV | 1 | 1 | ||
| HISTONE METHYLTRANSFERASE | PRMT | 12 | 3 | 0.052 |
| SET | 45 | 31 | ||
| DOT1 | 6 | 6 | ||
| Other | 1 | 1 | ||
| HISTONE DEMETHYLASE | JMJ | 20 | 12 | 0.399 |
| LSD | 2 | 3 | ||
| HISTONES | H1 | 5 | 9 | 0.004* |
| H2A | 13 | 19 | ||
| H2B | 12 | 17 | ||
| H3 | 19 | 24 | ||
| H4 | 12 | 16 | ||
| DNA METHYLATION | DNA methyltransferase | 1 | 0 | 1 |
| ALKB | 5 | 5 | ||
| DAMT-1 | 1 | 1 | ||
| NCRNA ASSOCIATED | Dicer | 1 | 1 | 0.609 |
| RdRP | 5 | 4 | ||
| Helicases | 7 | 4 | ||
| Argonautes | 23 | 20 | ||
| Drosha | 1 | 1 | ||
| Microprocessor complex | 2 | 1 | ||
| CHROMATIN REMODELERS | SWI/SNF | 2 | 2 | 1 |
| ISWI | 2 | 1 | ||
| INO80 | 1 | 1 | ||
| CHD | 3 | 4 | ||
| OTHERS | Histone kinase | 17 | 22 | 0.475 |
| Histone phosphatase | 5 | 6 | ||
| Histone ubiquitin transferase | 9 | 7 | ||
| Histone deubiquitinase | 6 | 6 | ||
| Misc. | 3 | 2 | ||
| TOTAL | 291 | 265 |
Table summary of epigenetic genes identified in P. pacificus and C. elegans. Values indicate number of genes recovered by our bioinformatic pipeline. Proteins were classified into families and subfamilies based on domain composition. P-values were calculated using Fisher's exact tests on 2 × 2 contingency tables of P. pacificus and C. elegans protein family sums vs the sum of the remaining epigenetic genes. *P < 0.05 (remains significant after Bonferroni correction).
| Family . | Subfamily . | P. pacificus . | C. elegans . | p value . |
|---|---|---|---|---|
| HISTONE ACETYLTRANSFERASE | CBP/P300 | 12 | 7 | 0.170 |
| GNAT | 15 | 11 | ||
| MYST | 7 | 4 | ||
| Other | 2 | 1 | ||
| HISTONE DEACETYLASE | Class I | 4 | 3 | 1 |
| Class II | 4 | 5 | ||
| Class III | 5 | 4 | ||
| Class IV | 1 | 1 | ||
| HISTONE METHYLTRANSFERASE | PRMT | 12 | 3 | 0.052 |
| SET | 45 | 31 | ||
| DOT1 | 6 | 6 | ||
| Other | 1 | 1 | ||
| HISTONE DEMETHYLASE | JMJ | 20 | 12 | 0.399 |
| LSD | 2 | 3 | ||
| HISTONES | H1 | 5 | 9 | 0.004* |
| H2A | 13 | 19 | ||
| H2B | 12 | 17 | ||
| H3 | 19 | 24 | ||
| H4 | 12 | 16 | ||
| DNA METHYLATION | DNA methyltransferase | 1 | 0 | 1 |
| ALKB | 5 | 5 | ||
| DAMT-1 | 1 | 1 | ||
| NCRNA ASSOCIATED | Dicer | 1 | 1 | 0.609 |
| RdRP | 5 | 4 | ||
| Helicases | 7 | 4 | ||
| Argonautes | 23 | 20 | ||
| Drosha | 1 | 1 | ||
| Microprocessor complex | 2 | 1 | ||
| CHROMATIN REMODELERS | SWI/SNF | 2 | 2 | 1 |
| ISWI | 2 | 1 | ||
| INO80 | 1 | 1 | ||
| CHD | 3 | 4 | ||
| OTHERS | Histone kinase | 17 | 22 | 0.475 |
| Histone phosphatase | 5 | 6 | ||
| Histone ubiquitin transferase | 9 | 7 | ||
| Histone deubiquitinase | 6 | 6 | ||
| Misc. | 3 | 2 | ||
| TOTAL | 291 | 265 |
| Family . | Subfamily . | P. pacificus . | C. elegans . | p value . |
|---|---|---|---|---|
| HISTONE ACETYLTRANSFERASE | CBP/P300 | 12 | 7 | 0.170 |
| GNAT | 15 | 11 | ||
| MYST | 7 | 4 | ||
| Other | 2 | 1 | ||
| HISTONE DEACETYLASE | Class I | 4 | 3 | 1 |
| Class II | 4 | 5 | ||
| Class III | 5 | 4 | ||
| Class IV | 1 | 1 | ||
| HISTONE METHYLTRANSFERASE | PRMT | 12 | 3 | 0.052 |
| SET | 45 | 31 | ||
| DOT1 | 6 | 6 | ||
| Other | 1 | 1 | ||
| HISTONE DEMETHYLASE | JMJ | 20 | 12 | 0.399 |
| LSD | 2 | 3 | ||
| HISTONES | H1 | 5 | 9 | 0.004* |
| H2A | 13 | 19 | ||
| H2B | 12 | 17 | ||
| H3 | 19 | 24 | ||
| H4 | 12 | 16 | ||
| DNA METHYLATION | DNA methyltransferase | 1 | 0 | 1 |
| ALKB | 5 | 5 | ||
| DAMT-1 | 1 | 1 | ||
| NCRNA ASSOCIATED | Dicer | 1 | 1 | 0.609 |
| RdRP | 5 | 4 | ||
| Helicases | 7 | 4 | ||
| Argonautes | 23 | 20 | ||
| Drosha | 1 | 1 | ||
| Microprocessor complex | 2 | 1 | ||
| CHROMATIN REMODELERS | SWI/SNF | 2 | 2 | 1 |
| ISWI | 2 | 1 | ||
| INO80 | 1 | 1 | ||
| CHD | 3 | 4 | ||
| OTHERS | Histone kinase | 17 | 22 | 0.475 |
| Histone phosphatase | 5 | 6 | ||
| Histone ubiquitin transferase | 9 | 7 | ||
| Histone deubiquitinase | 6 | 6 | ||
| Misc. | 3 | 2 | ||
| TOTAL | 291 | 265 |
Table summary of epigenetic genes identified in P. pacificus and C. elegans. Values indicate number of genes recovered by our bioinformatic pipeline. Proteins were classified into families and subfamilies based on domain composition. P-values were calculated using Fisher's exact tests on 2 × 2 contingency tables of P. pacificus and C. elegans protein family sums vs the sum of the remaining epigenetic genes. *P < 0.05 (remains significant after Bonferroni correction).
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