Results of univariate and multivariate analyses of the significant factors for systemic recurrence in patients with esophageal cancer
. | . | Univariate . | Multivariate . | ||||
---|---|---|---|---|---|---|---|
HR . | 95%CI . | P-value . | HR . | 95%CI . | P-value . | ||
Age | ≥70 vs. 70> | 1.19 | 0.79–1.80 | 0.402 | — | — | — |
Sex | female vs. male | 0.79 | 0.49–1.28 | 0.342 | — | — | — |
Tumor location | lower vs. middle/upper | 1.27 | 0.87–1.85 | 0.218 | — | — | — |
MIE or open | MIE vs. open | 0.70 | 0.44–1.10 | 0.119 | — | — | — |
Number of resected node | 50> vs. ≥50 | 1.18 | 0.75–1.85 | 0.471 | — | — | — |
Pathological response | 3–2 vs. 1b-0 | 2.67 | 1.72–4.13 | <0.0001 | 1.06 | 0.83–1.43 | 0.197 |
Tumor depth | ypT3–4 vs. ypT0–2 | 2.22 | 1.51–3.25 | <0.0001 | 1.03 | 0.63–1.69 | 0.894 |
Nodal status | ypN2–3 vs. ypN0–1 | 5.89 | 3.90–8.90 | <0.0001 | 4.56 | 2.92–7.10 | <0.0001 |
LV | LV(+) vs. LV(−) | 3.07 | 2.08–4.54 | <0.0001 | 1.56 | 0.97–2.59 | 0.066 |
. | . | Univariate . | Multivariate . | ||||
---|---|---|---|---|---|---|---|
HR . | 95%CI . | P-value . | HR . | 95%CI . | P-value . | ||
Age | ≥70 vs. 70> | 1.19 | 0.79–1.80 | 0.402 | — | — | — |
Sex | female vs. male | 0.79 | 0.49–1.28 | 0.342 | — | — | — |
Tumor location | lower vs. middle/upper | 1.27 | 0.87–1.85 | 0.218 | — | — | — |
MIE or open | MIE vs. open | 0.70 | 0.44–1.10 | 0.119 | — | — | — |
Number of resected node | 50> vs. ≥50 | 1.18 | 0.75–1.85 | 0.471 | — | — | — |
Pathological response | 3–2 vs. 1b-0 | 2.67 | 1.72–4.13 | <0.0001 | 1.06 | 0.83–1.43 | 0.197 |
Tumor depth | ypT3–4 vs. ypT0–2 | 2.22 | 1.51–3.25 | <0.0001 | 1.03 | 0.63–1.69 | 0.894 |
Nodal status | ypN2–3 vs. ypN0–1 | 5.89 | 3.90–8.90 | <0.0001 | 4.56 | 2.92–7.10 | <0.0001 |
LV | LV(+) vs. LV(−) | 3.07 | 2.08–4.54 | <0.0001 | 1.56 | 0.97–2.59 | 0.066 |
MIE, minimally invasive esophagectomy; LV, lymphovascular invasion.
Results of univariate and multivariate analyses of the significant factors for systemic recurrence in patients with esophageal cancer
. | . | Univariate . | Multivariate . | ||||
---|---|---|---|---|---|---|---|
HR . | 95%CI . | P-value . | HR . | 95%CI . | P-value . | ||
Age | ≥70 vs. 70> | 1.19 | 0.79–1.80 | 0.402 | — | — | — |
Sex | female vs. male | 0.79 | 0.49–1.28 | 0.342 | — | — | — |
Tumor location | lower vs. middle/upper | 1.27 | 0.87–1.85 | 0.218 | — | — | — |
MIE or open | MIE vs. open | 0.70 | 0.44–1.10 | 0.119 | — | — | — |
Number of resected node | 50> vs. ≥50 | 1.18 | 0.75–1.85 | 0.471 | — | — | — |
Pathological response | 3–2 vs. 1b-0 | 2.67 | 1.72–4.13 | <0.0001 | 1.06 | 0.83–1.43 | 0.197 |
Tumor depth | ypT3–4 vs. ypT0–2 | 2.22 | 1.51–3.25 | <0.0001 | 1.03 | 0.63–1.69 | 0.894 |
Nodal status | ypN2–3 vs. ypN0–1 | 5.89 | 3.90–8.90 | <0.0001 | 4.56 | 2.92–7.10 | <0.0001 |
LV | LV(+) vs. LV(−) | 3.07 | 2.08–4.54 | <0.0001 | 1.56 | 0.97–2.59 | 0.066 |
. | . | Univariate . | Multivariate . | ||||
---|---|---|---|---|---|---|---|
HR . | 95%CI . | P-value . | HR . | 95%CI . | P-value . | ||
Age | ≥70 vs. 70> | 1.19 | 0.79–1.80 | 0.402 | — | — | — |
Sex | female vs. male | 0.79 | 0.49–1.28 | 0.342 | — | — | — |
Tumor location | lower vs. middle/upper | 1.27 | 0.87–1.85 | 0.218 | — | — | — |
MIE or open | MIE vs. open | 0.70 | 0.44–1.10 | 0.119 | — | — | — |
Number of resected node | 50> vs. ≥50 | 1.18 | 0.75–1.85 | 0.471 | — | — | — |
Pathological response | 3–2 vs. 1b-0 | 2.67 | 1.72–4.13 | <0.0001 | 1.06 | 0.83–1.43 | 0.197 |
Tumor depth | ypT3–4 vs. ypT0–2 | 2.22 | 1.51–3.25 | <0.0001 | 1.03 | 0.63–1.69 | 0.894 |
Nodal status | ypN2–3 vs. ypN0–1 | 5.89 | 3.90–8.90 | <0.0001 | 4.56 | 2.92–7.10 | <0.0001 |
LV | LV(+) vs. LV(−) | 3.07 | 2.08–4.54 | <0.0001 | 1.56 | 0.97–2.59 | 0.066 |
MIE, minimally invasive esophagectomy; LV, lymphovascular invasion.
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