Table 3

Results of univariate and multivariate analyses of the significant factors for systemic recurrence in patients with esophageal cancer

UnivariateMultivariate
HR95%CIP-valueHR95%CIP-value
Age≥70 vs. 70>1.190.79–1.800.402
Sexfemale vs. male0.790.49–1.280.342
Tumor locationlower vs. middle/upper1.270.87–1.850.218
MIE or openMIE vs. open0.700.44–1.100.119
Number of resected node50> vs. ≥501.180.75–1.850.471
Pathological response3–2 vs. 1b-02.671.72–4.13<0.00011.060.83–1.430.197
Tumor depthypT3–4 vs. ypT0–22.221.51–3.25<0.00011.030.63–1.690.894
Nodal statusypN2–3 vs. ypN0–15.893.90–8.90<0.00014.562.92–7.10<0.0001
LVLV(+) vs. LV(−)3.072.08–4.54<0.00011.560.97–2.590.066
UnivariateMultivariate
HR95%CIP-valueHR95%CIP-value
Age≥70 vs. 70>1.190.79–1.800.402
Sexfemale vs. male0.790.49–1.280.342
Tumor locationlower vs. middle/upper1.270.87–1.850.218
MIE or openMIE vs. open0.700.44–1.100.119
Number of resected node50> vs. ≥501.180.75–1.850.471
Pathological response3–2 vs. 1b-02.671.72–4.13<0.00011.060.83–1.430.197
Tumor depthypT3–4 vs. ypT0–22.221.51–3.25<0.00011.030.63–1.690.894
Nodal statusypN2–3 vs. ypN0–15.893.90–8.90<0.00014.562.92–7.10<0.0001
LVLV(+) vs. LV(−)3.072.08–4.54<0.00011.560.97–2.590.066

MIE, minimally invasive esophagectomy; LV, lymphovascular invasion.

Table 3

Results of univariate and multivariate analyses of the significant factors for systemic recurrence in patients with esophageal cancer

UnivariateMultivariate
HR95%CIP-valueHR95%CIP-value
Age≥70 vs. 70>1.190.79–1.800.402
Sexfemale vs. male0.790.49–1.280.342
Tumor locationlower vs. middle/upper1.270.87–1.850.218
MIE or openMIE vs. open0.700.44–1.100.119
Number of resected node50> vs. ≥501.180.75–1.850.471
Pathological response3–2 vs. 1b-02.671.72–4.13<0.00011.060.83–1.430.197
Tumor depthypT3–4 vs. ypT0–22.221.51–3.25<0.00011.030.63–1.690.894
Nodal statusypN2–3 vs. ypN0–15.893.90–8.90<0.00014.562.92–7.10<0.0001
LVLV(+) vs. LV(−)3.072.08–4.54<0.00011.560.97–2.590.066
UnivariateMultivariate
HR95%CIP-valueHR95%CIP-value
Age≥70 vs. 70>1.190.79–1.800.402
Sexfemale vs. male0.790.49–1.280.342
Tumor locationlower vs. middle/upper1.270.87–1.850.218
MIE or openMIE vs. open0.700.44–1.100.119
Number of resected node50> vs. ≥501.180.75–1.850.471
Pathological response3–2 vs. 1b-02.671.72–4.13<0.00011.060.83–1.430.197
Tumor depthypT3–4 vs. ypT0–22.221.51–3.25<0.00011.030.63–1.690.894
Nodal statusypN2–3 vs. ypN0–15.893.90–8.90<0.00014.562.92–7.10<0.0001
LVLV(+) vs. LV(−)3.072.08–4.54<0.00011.560.97–2.590.066

MIE, minimally invasive esophagectomy; LV, lymphovascular invasion.

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