Table 1

Study characteristics

StudyCountryNumber of centresStudy intervalPatient selectionOperation typeOperative indication
Alder et al. 202119UK1July 2015–July 2016Inclusion: all patients over the age of 70 years who underwent emergency laparotomy
Exclusion: not stated
Emergency laparotomy and major laparoscopic casesNot further specified
Carter et al. 202020UK4920 March–19 June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: not stated
Emergency laparotomy and major laparoscopy casesGastrointestinal pathology or return to theatre for complication
Ethiraj et al. 202221India1March 2021–December 2021Inclusion: > 60 years undergoing emergency laparotomy for acute surgical conditions
Exclusion: patients lost to follow-up, poly trauma patients, and patients with associated medical emergencies
Emergency laparotomyEmergency laparotomy for acute surgical conditions (obstruction, perforation, abdominal abscess, ischaemia)
Hajibandeh et al. 202422UK1January 2017–January 2022Inclusion: all patients aged over 18 who underwent emergency laparotomy due to non-traumatic abdominal pathology during the time interval
Exclusion: patients who underwent emergency laparotomy due to abdominal trauma
Emergency laparotomySmall and large bowel obstruction, perforated peptic ulcer, small and colonic bowel perforation, ischaemia, intra-abdominal collection, colitis, anastomotic leak
Isand et al. 202323UK1January 2018–June 2021Inclusion: patients who underwent a major emergency abdominal operation corresponded to the NELA inclusion criteria from the same time interval
Exclusion: duplicates or missing critical data, not enough information to calculate P-POSSUM score, or NELA score
Emergency laparotomy and major laparoscopic casesMajor emergency abdominal operation corresponded to the NELA inclusion criteria
Palaniappan et al. 202225UK18November 2017–October 2018Inclusion: patients aged 18 and above; admitted or underwent expedited, urgent, or emergency open laparotomy, laparoscopic abdominal procedures
Exclusion: <18 years, diagnostic or elective laparotomy/laparoscopy, emergency hernia repair without bowel resection or division of adhesions, all oesophageal, pancreatic, splenic, hepatobiliary, appendiceal, urological, vascular, organ transplant, trauma, obstetric or gynaecological complications
Emergency laparotomy and major laparoscopic casesMajor procedures limited to the stomach, small intestine, large intestine, rectum, intraperitoneal haematomas and abscesses, incarcerated hernias, substantial abdominal wound dehiscence and returns to theatre for elective general surgery complications
Parmar et al. 202126UK49March 2017–June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: <18; elective; diagnostic where no subsequent procedure is performed; appendicectomy; cholecystectomy; non-elective hernia repair without bowel resection or division of adhesions; minor abdominal wound dehiscence; non-elective formation of a colostomy or ileostomy as laparoscopic; vascular surgery; caesarean section or obstetric laparotomies
Emergency laparotomy and major laparoscopic casesGastrointestinal pathology and/or return to theatre for any major postoperative complication/dehiscence
Ramsay et al. 202227UK17November 2017–October 2018Inclusion: patients undergoing emergency laparotomy
Exclusion: previous surgical procedures during same admission
Emergency laparotomy and major laparoscopic casesNot further specified
Vilches-Moraga et al. 202028UK1September 2014–March 2017Inclusion: aged 75 years or older undergoing emergency laparotomy within the time interval
Exclusion: remaining an inpatient > 90 days before the final date of data collection. Patients who had more than one laparotomy on separate admissions were only included for index admission
Emergency laparotomy and major laparoscopic casesBowel obstruction/perforation, hernias, peritonitis, ulcers, diverticulitis, ischaemia
Youssef et al. 202229UK1December 2018–May 2021Inclusion: all patients aged 65 years and older who underwent emergency laparotomy
Exclusion: patients who had previously undergone surgical procedures during the same admission were excluded
Emergency laparotomy and major laparoscopic casesNot further specified
Park et al. 202430New Zealand4August 2017–September 2022Inclusion: adult patients aged 55 years or older who were undergoing emergency laparotomy with a recorded CFS
Exclusion: < 55, elective laparotomy or laparoscopic procedures, appendicectomy, cholecystectomy, non-elective (urgent or emergent) hernia repair without bowel resection, vascular, gynaecological, urological or transplant procedures
Emergency laparotomy and major laparoscopic casesObstruction, perforation, ischaemia, peritonitis, volvulus, haemorrhage, anastomotic leak, relook, abdominal wall abscess, wound dehiscence, fistula, stricture
Mak et al. 202424UK1January 2013–December 2016Inclusion: all patients with colorectal cancer admitted as emergency, not diagnosed via GP referral and elective investigation, and had emergency colorectal cancer operations as primary intervention within the time interval
Exclusion: not specified
Emergency laparotomy and major laparoscopic casesEmergency operations for colorectal cancer including for perforation. Not further specified
StudyCountryNumber of centresStudy intervalPatient selectionOperation typeOperative indication
Alder et al. 202119UK1July 2015–July 2016Inclusion: all patients over the age of 70 years who underwent emergency laparotomy
Exclusion: not stated
Emergency laparotomy and major laparoscopic casesNot further specified
Carter et al. 202020UK4920 March–19 June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: not stated
Emergency laparotomy and major laparoscopy casesGastrointestinal pathology or return to theatre for complication
Ethiraj et al. 202221India1March 2021–December 2021Inclusion: > 60 years undergoing emergency laparotomy for acute surgical conditions
Exclusion: patients lost to follow-up, poly trauma patients, and patients with associated medical emergencies
Emergency laparotomyEmergency laparotomy for acute surgical conditions (obstruction, perforation, abdominal abscess, ischaemia)
Hajibandeh et al. 202422UK1January 2017–January 2022Inclusion: all patients aged over 18 who underwent emergency laparotomy due to non-traumatic abdominal pathology during the time interval
Exclusion: patients who underwent emergency laparotomy due to abdominal trauma
Emergency laparotomySmall and large bowel obstruction, perforated peptic ulcer, small and colonic bowel perforation, ischaemia, intra-abdominal collection, colitis, anastomotic leak
Isand et al. 202323UK1January 2018–June 2021Inclusion: patients who underwent a major emergency abdominal operation corresponded to the NELA inclusion criteria from the same time interval
Exclusion: duplicates or missing critical data, not enough information to calculate P-POSSUM score, or NELA score
Emergency laparotomy and major laparoscopic casesMajor emergency abdominal operation corresponded to the NELA inclusion criteria
Palaniappan et al. 202225UK18November 2017–October 2018Inclusion: patients aged 18 and above; admitted or underwent expedited, urgent, or emergency open laparotomy, laparoscopic abdominal procedures
Exclusion: <18 years, diagnostic or elective laparotomy/laparoscopy, emergency hernia repair without bowel resection or division of adhesions, all oesophageal, pancreatic, splenic, hepatobiliary, appendiceal, urological, vascular, organ transplant, trauma, obstetric or gynaecological complications
Emergency laparotomy and major laparoscopic casesMajor procedures limited to the stomach, small intestine, large intestine, rectum, intraperitoneal haematomas and abscesses, incarcerated hernias, substantial abdominal wound dehiscence and returns to theatre for elective general surgery complications
Parmar et al. 202126UK49March 2017–June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: <18; elective; diagnostic where no subsequent procedure is performed; appendicectomy; cholecystectomy; non-elective hernia repair without bowel resection or division of adhesions; minor abdominal wound dehiscence; non-elective formation of a colostomy or ileostomy as laparoscopic; vascular surgery; caesarean section or obstetric laparotomies
Emergency laparotomy and major laparoscopic casesGastrointestinal pathology and/or return to theatre for any major postoperative complication/dehiscence
Ramsay et al. 202227UK17November 2017–October 2018Inclusion: patients undergoing emergency laparotomy
Exclusion: previous surgical procedures during same admission
Emergency laparotomy and major laparoscopic casesNot further specified
Vilches-Moraga et al. 202028UK1September 2014–March 2017Inclusion: aged 75 years or older undergoing emergency laparotomy within the time interval
Exclusion: remaining an inpatient > 90 days before the final date of data collection. Patients who had more than one laparotomy on separate admissions were only included for index admission
Emergency laparotomy and major laparoscopic casesBowel obstruction/perforation, hernias, peritonitis, ulcers, diverticulitis, ischaemia
Youssef et al. 202229UK1December 2018–May 2021Inclusion: all patients aged 65 years and older who underwent emergency laparotomy
Exclusion: patients who had previously undergone surgical procedures during the same admission were excluded
Emergency laparotomy and major laparoscopic casesNot further specified
Park et al. 202430New Zealand4August 2017–September 2022Inclusion: adult patients aged 55 years or older who were undergoing emergency laparotomy with a recorded CFS
Exclusion: < 55, elective laparotomy or laparoscopic procedures, appendicectomy, cholecystectomy, non-elective (urgent or emergent) hernia repair without bowel resection, vascular, gynaecological, urological or transplant procedures
Emergency laparotomy and major laparoscopic casesObstruction, perforation, ischaemia, peritonitis, volvulus, haemorrhage, anastomotic leak, relook, abdominal wall abscess, wound dehiscence, fistula, stricture
Mak et al. 202424UK1January 2013–December 2016Inclusion: all patients with colorectal cancer admitted as emergency, not diagnosed via GP referral and elective investigation, and had emergency colorectal cancer operations as primary intervention within the time interval
Exclusion: not specified
Emergency laparotomy and major laparoscopic casesEmergency operations for colorectal cancer including for perforation. Not further specified

NELA, National Emergency Laparotomy Audit; P-POSSUM, Portsmouth-Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM); CFS, Clinical Frailty Scale; GP, General Practitioner.

Table 1

Study characteristics

StudyCountryNumber of centresStudy intervalPatient selectionOperation typeOperative indication
Alder et al. 202119UK1July 2015–July 2016Inclusion: all patients over the age of 70 years who underwent emergency laparotomy
Exclusion: not stated
Emergency laparotomy and major laparoscopic casesNot further specified
Carter et al. 202020UK4920 March–19 June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: not stated
Emergency laparotomy and major laparoscopy casesGastrointestinal pathology or return to theatre for complication
Ethiraj et al. 202221India1March 2021–December 2021Inclusion: > 60 years undergoing emergency laparotomy for acute surgical conditions
Exclusion: patients lost to follow-up, poly trauma patients, and patients with associated medical emergencies
Emergency laparotomyEmergency laparotomy for acute surgical conditions (obstruction, perforation, abdominal abscess, ischaemia)
Hajibandeh et al. 202422UK1January 2017–January 2022Inclusion: all patients aged over 18 who underwent emergency laparotomy due to non-traumatic abdominal pathology during the time interval
Exclusion: patients who underwent emergency laparotomy due to abdominal trauma
Emergency laparotomySmall and large bowel obstruction, perforated peptic ulcer, small and colonic bowel perforation, ischaemia, intra-abdominal collection, colitis, anastomotic leak
Isand et al. 202323UK1January 2018–June 2021Inclusion: patients who underwent a major emergency abdominal operation corresponded to the NELA inclusion criteria from the same time interval
Exclusion: duplicates or missing critical data, not enough information to calculate P-POSSUM score, or NELA score
Emergency laparotomy and major laparoscopic casesMajor emergency abdominal operation corresponded to the NELA inclusion criteria
Palaniappan et al. 202225UK18November 2017–October 2018Inclusion: patients aged 18 and above; admitted or underwent expedited, urgent, or emergency open laparotomy, laparoscopic abdominal procedures
Exclusion: <18 years, diagnostic or elective laparotomy/laparoscopy, emergency hernia repair without bowel resection or division of adhesions, all oesophageal, pancreatic, splenic, hepatobiliary, appendiceal, urological, vascular, organ transplant, trauma, obstetric or gynaecological complications
Emergency laparotomy and major laparoscopic casesMajor procedures limited to the stomach, small intestine, large intestine, rectum, intraperitoneal haematomas and abscesses, incarcerated hernias, substantial abdominal wound dehiscence and returns to theatre for elective general surgery complications
Parmar et al. 202126UK49March 2017–June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: <18; elective; diagnostic where no subsequent procedure is performed; appendicectomy; cholecystectomy; non-elective hernia repair without bowel resection or division of adhesions; minor abdominal wound dehiscence; non-elective formation of a colostomy or ileostomy as laparoscopic; vascular surgery; caesarean section or obstetric laparotomies
Emergency laparotomy and major laparoscopic casesGastrointestinal pathology and/or return to theatre for any major postoperative complication/dehiscence
Ramsay et al. 202227UK17November 2017–October 2018Inclusion: patients undergoing emergency laparotomy
Exclusion: previous surgical procedures during same admission
Emergency laparotomy and major laparoscopic casesNot further specified
Vilches-Moraga et al. 202028UK1September 2014–March 2017Inclusion: aged 75 years or older undergoing emergency laparotomy within the time interval
Exclusion: remaining an inpatient > 90 days before the final date of data collection. Patients who had more than one laparotomy on separate admissions were only included for index admission
Emergency laparotomy and major laparoscopic casesBowel obstruction/perforation, hernias, peritonitis, ulcers, diverticulitis, ischaemia
Youssef et al. 202229UK1December 2018–May 2021Inclusion: all patients aged 65 years and older who underwent emergency laparotomy
Exclusion: patients who had previously undergone surgical procedures during the same admission were excluded
Emergency laparotomy and major laparoscopic casesNot further specified
Park et al. 202430New Zealand4August 2017–September 2022Inclusion: adult patients aged 55 years or older who were undergoing emergency laparotomy with a recorded CFS
Exclusion: < 55, elective laparotomy or laparoscopic procedures, appendicectomy, cholecystectomy, non-elective (urgent or emergent) hernia repair without bowel resection, vascular, gynaecological, urological or transplant procedures
Emergency laparotomy and major laparoscopic casesObstruction, perforation, ischaemia, peritonitis, volvulus, haemorrhage, anastomotic leak, relook, abdominal wall abscess, wound dehiscence, fistula, stricture
Mak et al. 202424UK1January 2013–December 2016Inclusion: all patients with colorectal cancer admitted as emergency, not diagnosed via GP referral and elective investigation, and had emergency colorectal cancer operations as primary intervention within the time interval
Exclusion: not specified
Emergency laparotomy and major laparoscopic casesEmergency operations for colorectal cancer including for perforation. Not further specified
StudyCountryNumber of centresStudy intervalPatient selectionOperation typeOperative indication
Alder et al. 202119UK1July 2015–July 2016Inclusion: all patients over the age of 70 years who underwent emergency laparotomy
Exclusion: not stated
Emergency laparotomy and major laparoscopic casesNot further specified
Carter et al. 202020UK4920 March–19 June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: not stated
Emergency laparotomy and major laparoscopy casesGastrointestinal pathology or return to theatre for complication
Ethiraj et al. 202221India1March 2021–December 2021Inclusion: > 60 years undergoing emergency laparotomy for acute surgical conditions
Exclusion: patients lost to follow-up, poly trauma patients, and patients with associated medical emergencies
Emergency laparotomyEmergency laparotomy for acute surgical conditions (obstruction, perforation, abdominal abscess, ischaemia)
Hajibandeh et al. 202422UK1January 2017–January 2022Inclusion: all patients aged over 18 who underwent emergency laparotomy due to non-traumatic abdominal pathology during the time interval
Exclusion: patients who underwent emergency laparotomy due to abdominal trauma
Emergency laparotomySmall and large bowel obstruction, perforated peptic ulcer, small and colonic bowel perforation, ischaemia, intra-abdominal collection, colitis, anastomotic leak
Isand et al. 202323UK1January 2018–June 2021Inclusion: patients who underwent a major emergency abdominal operation corresponded to the NELA inclusion criteria from the same time interval
Exclusion: duplicates or missing critical data, not enough information to calculate P-POSSUM score, or NELA score
Emergency laparotomy and major laparoscopic casesMajor emergency abdominal operation corresponded to the NELA inclusion criteria
Palaniappan et al. 202225UK18November 2017–October 2018Inclusion: patients aged 18 and above; admitted or underwent expedited, urgent, or emergency open laparotomy, laparoscopic abdominal procedures
Exclusion: <18 years, diagnostic or elective laparotomy/laparoscopy, emergency hernia repair without bowel resection or division of adhesions, all oesophageal, pancreatic, splenic, hepatobiliary, appendiceal, urological, vascular, organ transplant, trauma, obstetric or gynaecological complications
Emergency laparotomy and major laparoscopic casesMajor procedures limited to the stomach, small intestine, large intestine, rectum, intraperitoneal haematomas and abscesses, incarcerated hernias, substantial abdominal wound dehiscence and returns to theatre for elective general surgery complications
Parmar et al. 202126UK49March 2017–June 2017Inclusion: if undergoing an expedited, urgent or emergency surgical abdominal procedure for gastrointestinal pathology (laparoscopic or open) and/or return to theatre for any major postoperative complication/dehiscence
Exclusion: <18; elective; diagnostic where no subsequent procedure is performed; appendicectomy; cholecystectomy; non-elective hernia repair without bowel resection or division of adhesions; minor abdominal wound dehiscence; non-elective formation of a colostomy or ileostomy as laparoscopic; vascular surgery; caesarean section or obstetric laparotomies
Emergency laparotomy and major laparoscopic casesGastrointestinal pathology and/or return to theatre for any major postoperative complication/dehiscence
Ramsay et al. 202227UK17November 2017–October 2018Inclusion: patients undergoing emergency laparotomy
Exclusion: previous surgical procedures during same admission
Emergency laparotomy and major laparoscopic casesNot further specified
Vilches-Moraga et al. 202028UK1September 2014–March 2017Inclusion: aged 75 years or older undergoing emergency laparotomy within the time interval
Exclusion: remaining an inpatient > 90 days before the final date of data collection. Patients who had more than one laparotomy on separate admissions were only included for index admission
Emergency laparotomy and major laparoscopic casesBowel obstruction/perforation, hernias, peritonitis, ulcers, diverticulitis, ischaemia
Youssef et al. 202229UK1December 2018–May 2021Inclusion: all patients aged 65 years and older who underwent emergency laparotomy
Exclusion: patients who had previously undergone surgical procedures during the same admission were excluded
Emergency laparotomy and major laparoscopic casesNot further specified
Park et al. 202430New Zealand4August 2017–September 2022Inclusion: adult patients aged 55 years or older who were undergoing emergency laparotomy with a recorded CFS
Exclusion: < 55, elective laparotomy or laparoscopic procedures, appendicectomy, cholecystectomy, non-elective (urgent or emergent) hernia repair without bowel resection, vascular, gynaecological, urological or transplant procedures
Emergency laparotomy and major laparoscopic casesObstruction, perforation, ischaemia, peritonitis, volvulus, haemorrhage, anastomotic leak, relook, abdominal wall abscess, wound dehiscence, fistula, stricture
Mak et al. 202424UK1January 2013–December 2016Inclusion: all patients with colorectal cancer admitted as emergency, not diagnosed via GP referral and elective investigation, and had emergency colorectal cancer operations as primary intervention within the time interval
Exclusion: not specified
Emergency laparotomy and major laparoscopic casesEmergency operations for colorectal cancer including for perforation. Not further specified

NELA, National Emergency Laparotomy Audit; P-POSSUM, Portsmouth-Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM); CFS, Clinical Frailty Scale; GP, General Practitioner.

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