Adjusted Odds Ratios and 95% CIs for the Associations of Continued Antifungal Prophylaxis With Patient Characteristics
. | No. . | Multivariate Analysis . | ||
---|---|---|---|---|
. | C-AFPx . | N-AFPx . | Adjusted ORa (95% CI) . | P Valueb . |
Recipient sex | ||||
Female | 95 | 86 | 1 [Reference] | |
Male | 122 | 84 | 1.56 (.96–2.53) | .072 |
Primary diagnosis | ||||
Acute lymphocytic leukemia | 47 | 38 | 1 [Reference] | |
Acute myeloid leukemia | 116 | 67 | 1.92 (1.02–3.61) | .045 |
Myelodysplastic syndrome | 19 | 16 | 0.68 (.26–1.81) | .440 |
Others | 35 | 49 | 0.52 (.25–1.09) | .083 |
>30 d length of stay | ||||
No | 92 | 130 | 1 [Reference] | |
Yes | 125 | 40 | 3.22 (1.93–5.39) | <.0001 |
Maximum grade of GVHD onset from transplant to discharge | ||||
0–1 | 147 | 163 | 1 [Reference] | |
2–4 | 70 | 7 | 5.69 (2.33–13.89) | .0001 |
>5 d of corticosteroids | ||||
No | 129 | 155 | 1 [Reference] | |
Yes | 88 | 15 | 5.21 (2.69–10.11) | <.001 |
. | No. . | Multivariate Analysis . | ||
---|---|---|---|---|
. | C-AFPx . | N-AFPx . | Adjusted ORa (95% CI) . | P Valueb . |
Recipient sex | ||||
Female | 95 | 86 | 1 [Reference] | |
Male | 122 | 84 | 1.56 (.96–2.53) | .072 |
Primary diagnosis | ||||
Acute lymphocytic leukemia | 47 | 38 | 1 [Reference] | |
Acute myeloid leukemia | 116 | 67 | 1.92 (1.02–3.61) | .045 |
Myelodysplastic syndrome | 19 | 16 | 0.68 (.26–1.81) | .440 |
Others | 35 | 49 | 0.52 (.25–1.09) | .083 |
>30 d length of stay | ||||
No | 92 | 130 | 1 [Reference] | |
Yes | 125 | 40 | 3.22 (1.93–5.39) | <.0001 |
Maximum grade of GVHD onset from transplant to discharge | ||||
0–1 | 147 | 163 | 1 [Reference] | |
2–4 | 70 | 7 | 5.69 (2.33–13.89) | .0001 |
>5 d of corticosteroids | ||||
No | 129 | 155 | 1 [Reference] | |
Yes | 88 | 15 | 5.21 (2.69–10.11) | <.001 |
Abbreviations: GVHD, graft-vs-host disease; C-AFPx, continued antifungal prophylaxis; N-AFPx, no antifungal prophylaxis; OR, odds ratio.
aORs (95% CIs) are from multivariate logistic regression model. Characteristics listed in the table are mutually adjusted.
bBased on Wald test. Bold indicates P < .05.
Adjusted Odds Ratios and 95% CIs for the Associations of Continued Antifungal Prophylaxis With Patient Characteristics
. | No. . | Multivariate Analysis . | ||
---|---|---|---|---|
. | C-AFPx . | N-AFPx . | Adjusted ORa (95% CI) . | P Valueb . |
Recipient sex | ||||
Female | 95 | 86 | 1 [Reference] | |
Male | 122 | 84 | 1.56 (.96–2.53) | .072 |
Primary diagnosis | ||||
Acute lymphocytic leukemia | 47 | 38 | 1 [Reference] | |
Acute myeloid leukemia | 116 | 67 | 1.92 (1.02–3.61) | .045 |
Myelodysplastic syndrome | 19 | 16 | 0.68 (.26–1.81) | .440 |
Others | 35 | 49 | 0.52 (.25–1.09) | .083 |
>30 d length of stay | ||||
No | 92 | 130 | 1 [Reference] | |
Yes | 125 | 40 | 3.22 (1.93–5.39) | <.0001 |
Maximum grade of GVHD onset from transplant to discharge | ||||
0–1 | 147 | 163 | 1 [Reference] | |
2–4 | 70 | 7 | 5.69 (2.33–13.89) | .0001 |
>5 d of corticosteroids | ||||
No | 129 | 155 | 1 [Reference] | |
Yes | 88 | 15 | 5.21 (2.69–10.11) | <.001 |
. | No. . | Multivariate Analysis . | ||
---|---|---|---|---|
. | C-AFPx . | N-AFPx . | Adjusted ORa (95% CI) . | P Valueb . |
Recipient sex | ||||
Female | 95 | 86 | 1 [Reference] | |
Male | 122 | 84 | 1.56 (.96–2.53) | .072 |
Primary diagnosis | ||||
Acute lymphocytic leukemia | 47 | 38 | 1 [Reference] | |
Acute myeloid leukemia | 116 | 67 | 1.92 (1.02–3.61) | .045 |
Myelodysplastic syndrome | 19 | 16 | 0.68 (.26–1.81) | .440 |
Others | 35 | 49 | 0.52 (.25–1.09) | .083 |
>30 d length of stay | ||||
No | 92 | 130 | 1 [Reference] | |
Yes | 125 | 40 | 3.22 (1.93–5.39) | <.0001 |
Maximum grade of GVHD onset from transplant to discharge | ||||
0–1 | 147 | 163 | 1 [Reference] | |
2–4 | 70 | 7 | 5.69 (2.33–13.89) | .0001 |
>5 d of corticosteroids | ||||
No | 129 | 155 | 1 [Reference] | |
Yes | 88 | 15 | 5.21 (2.69–10.11) | <.001 |
Abbreviations: GVHD, graft-vs-host disease; C-AFPx, continued antifungal prophylaxis; N-AFPx, no antifungal prophylaxis; OR, odds ratio.
aORs (95% CIs) are from multivariate logistic regression model. Characteristics listed in the table are mutually adjusted.
bBased on Wald test. Bold indicates P < .05.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.