Table 3. Open in new tab Distribution of...

	Total (n = 3 874 307)	3–7 d (n = 1 557 743)	8–14 d (n = 2 316 564)
First-line	2 010 316	100	507 635	25.3	1 502 681	74.7
Amoxicillin-clavulanate	1 492 202	100	411 746	27.6	1 080 456	72.4
Amoxicillin	518 114	100	95 889	18.5	422 225	81.5
Second-line	480 246	100	175 621	36.6	304 625	63.4
Doxycycline	350 403	100	129 975	37.1	220 428	62.9
Fluoroquinolones^a	129 843	100	45 646	35.2	84 197	64.8
Guideline discordant	1 383 745	100	874 487	63.2	509 258	36.8
Macrolides^b	852 274	100	791 794	92.9	60 480	7.1
Cephalosporins^c	425 176	100	57 599	13.5	367 577	86.5
Other^d	106 295	100	25 094	23.6	81 201	76.4

	Total (n = 3 874 307)	3–7 d (n = 1 557 743)	8–14 d (n = 2 316 564)
First-line	2 010 316	100	507 635	25.3	1 502 681	74.7
Amoxicillin-clavulanate	1 492 202	100	411 746	27.6	1 080 456	72.4
Amoxicillin	518 114	100	95 889	18.5	422 225	81.5
Second-line	480 246	100	175 621	36.6	304 625	63.4
Doxycycline	350 403	100	129 975	37.1	220 428	62.9
Fluoroquinolones^a	129 843	100	45 646	35.2	84 197	64.8
Guideline discordant	1 383 745	100	874 487	63.2	509 258	36.8
Macrolides^b	852 274	100	791 794	92.9	60 480	7.1
Cephalosporins^c	425 176	100	57 599	13.5	367 577	86.5
Other^d	106 295	100	25 094	23.6	81 201	76.4

Table 3.

Distribution of Antibiotics Prescribed in Outpatient Encounters of Commercially Insured Adults With Acute Sinusitis by Duration, United States, 2016–2020

	Total (n = 3 874 307)		3–7 d (n = 1 557 743)		8–14 d (n = 2 316 564)
Antibiotic Agent	No.	%	No.	%	No.	%
First-line	2 010 316	100	507 635	25.3	1 502 681	74.7
Amoxicillin-clavulanate	1 492 202	100	411 746	27.6	1 080 456	72.4
Amoxicillin	518 114	100	95 889	18.5	422 225	81.5
Second-line	480 246	100	175 621	36.6	304 625	63.4
Doxycycline	350 403	100	129 975	37.1	220 428	62.9
Fluoroquinolones^a	129 843	100	45 646	35.2	84 197	64.8
Guideline discordant	1 383 745	100	874 487	63.2	509 258	36.8
Macrolides^b	852 274	100	791 794	92.9	60 480	7.1
Cephalosporins^c	425 176	100	57 599	13.5	367 577	86.5
Other^d	106 295	100	25 094	23.6	81 201	76.4

	Total (n = 3 874 307)		3–7 d (n = 1 557 743)		8–14 d (n = 2 316 564)
Antibiotic Agent	No.	%	No.	%	No.	%
First-line	2 010 316	100	507 635	25.3	1 502 681	74.7
Amoxicillin-clavulanate	1 492 202	100	411 746	27.6	1 080 456	72.4
Amoxicillin	518 114	100	95 889	18.5	422 225	81.5
Second-line	480 246	100	175 621	36.6	304 625	63.4
Doxycycline	350 403	100	129 975	37.1	220 428	62.9
Fluoroquinolones^a	129 843	100	45 646	35.2	84 197	64.8
Guideline discordant	1 383 745	100	874 487	63.2	509 258	36.8
Macrolides^b	852 274	100	791 794	92.9	60 480	7.1
Cephalosporins^c	425 176	100	57 599	13.5	367 577	86.5
Other^d	106 295	100	25 094	23.6	81 201	76.4

^aFluoroquinolones include levofloxacin and moxifloxacin.

^bMacrolides include azithromycin and clarithromycin.

^cCephalosporins include cefaclor, cefadroxil, cefdinir, cefixime, cefpodoxime, cefprozil, ceftibuten, cefuroxime, and cephalexin.

^dOther includes ciprofloxacin, clindamycin, dicloxacillin, erythromycin, fosfomycin, linezolid, metronidazole, minocycline, nitrofurantoin, ofloxacin, penicillin, rifampin, sulfamethoxazole-trimethoprim, tetracycline, trimethoprim, and vancomycin.

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