| . | Patient #1 . | Patient #2 . | Patient #3 . | Reference ranges . |
|---|---|---|---|---|
| 25(OH)D | aDeficiency: ≤ 20 (≤ 50 nmol/L) | |||
| Before VitD | 11.7 ng/mL (29 nmol/L) | 10.8 ng/mL (27 nmol/L) | 12.3 (30.7 nmol/L) | Insufficiency: 21-29 (52-72 nmol/L) |
| After VitD | 31.7 (79.1 nmol/L) | 31.8 (79.4 nmol/L) | 33.8 (84.4 nmol/L) | Sufficiency: ≥ 30 (75 nmol/L) |
| 1,25(OH)2D | ||||
| Before VitD | 51 pg/mL (127 pmol/L) | 33 pg/mL (82 pmol/L) | 19 pg/mL (47 pmol/L) | Adults: |
| After VitD | 34 (85 pmol/L) | 29 (72 pmol/L) | 22 (55 pmol/L) | 18-72 pg/mL (45-180 pmol/L) |
| 24,25(OH)2D | ||||
| Before VitD | 0.5 ng/mL (1.3 nmol/L) | 0.8 ng/mL (2 nmol/L) | 0.9 ng/mL (2.3 nmol/L) | ̶ |
| After VitD | 2.9 ng/mL (7.2 nmol/L) | 2.8 ng/mL (7 nmol/L) | 4.1 ng/mL (10.2 nmol/L) | |
| Calcium | ||||
| Before VitD | 9.3 mg/dL (2.32 mmol/L) | 9.6 mg/dL (2.395 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | Males ≥ 20 yrs: |
| After VitD | 9.1 (2.27 mmol/L) | 9.4 mg/dL (2.345 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | 8.6-10.3 mg/dL (2.2-2.6 mmol/L) |
| Phosphorus | ||||
| Before VitD | 3.1 (1 mmol/L) | 3.3 (1.1 mmol/L) | 4.2 (1.36 mmol/L) | 2.5-4.5 mg/dL (0.8-1.5 mmol/L) |
| After VitD | 3.2 (1 mmol/L) | 4 (1.3 mmol/L) | 4.4 (1.42 mmol/L) | |
| iPTH | ||||
| Before VitD | 62 pg/mL (6.6 pmol/L) | 29 pg/mL (3.1 pmol/L) | 51 pg/mL (5.4 pmol/L) | ≥19 yrs: |
| After VitD | 41 pg/mL (4.4 pmol/L) | 30 pg/mL (3.2 pmol/L) | 54 pg/mL (5.7 pmol/L) | 14-64 pg/mL (1.5-6.8 pmol/L) |
| iFGF23 | ||||
| Before VitD | 50.4 pg/mL) | 59.9 pg/mL) | 57.1 pg/mL) | 18.6-59.8 pg/mL |
| After VitD | 60.5 pg/mL) | 67.6 pg/mL) | 62.6 pg/mL) | |
| ßCTX | Males: 30-39 yrs (70-780 pg/mL) | |||
| Before VitD | 425 pg/mL | 189 pg/mL | 365 pg/mL | 40-49 yrs (60-700 pg/mL) |
| After VitD | 578 pg/mL | 182 pg/mL | 317 pg/mL | 50-68 yrs (87-345 pg/mL) |
| P1NP | Males: | |||
| Before VitD | 32 mcg/L | 23 mcg/L | 40 mcg/L | 23-60 yrs (30-110 mcg/L) |
| After VitD | 31 mcg/L | 25 mcg/L | 35 mcg/L | > 60 yrs (not stablished) |
| . | Patient #1 . | Patient #2 . | Patient #3 . | Reference ranges . |
|---|---|---|---|---|
| 25(OH)D | aDeficiency: ≤ 20 (≤ 50 nmol/L) | |||
| Before VitD | 11.7 ng/mL (29 nmol/L) | 10.8 ng/mL (27 nmol/L) | 12.3 (30.7 nmol/L) | Insufficiency: 21-29 (52-72 nmol/L) |
| After VitD | 31.7 (79.1 nmol/L) | 31.8 (79.4 nmol/L) | 33.8 (84.4 nmol/L) | Sufficiency: ≥ 30 (75 nmol/L) |
| 1,25(OH)2D | ||||
| Before VitD | 51 pg/mL (127 pmol/L) | 33 pg/mL (82 pmol/L) | 19 pg/mL (47 pmol/L) | Adults: |
| After VitD | 34 (85 pmol/L) | 29 (72 pmol/L) | 22 (55 pmol/L) | 18-72 pg/mL (45-180 pmol/L) |
| 24,25(OH)2D | ||||
| Before VitD | 0.5 ng/mL (1.3 nmol/L) | 0.8 ng/mL (2 nmol/L) | 0.9 ng/mL (2.3 nmol/L) | ̶ |
| After VitD | 2.9 ng/mL (7.2 nmol/L) | 2.8 ng/mL (7 nmol/L) | 4.1 ng/mL (10.2 nmol/L) | |
| Calcium | ||||
| Before VitD | 9.3 mg/dL (2.32 mmol/L) | 9.6 mg/dL (2.395 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | Males ≥ 20 yrs: |
| After VitD | 9.1 (2.27 mmol/L) | 9.4 mg/dL (2.345 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | 8.6-10.3 mg/dL (2.2-2.6 mmol/L) |
| Phosphorus | ||||
| Before VitD | 3.1 (1 mmol/L) | 3.3 (1.1 mmol/L) | 4.2 (1.36 mmol/L) | 2.5-4.5 mg/dL (0.8-1.5 mmol/L) |
| After VitD | 3.2 (1 mmol/L) | 4 (1.3 mmol/L) | 4.4 (1.42 mmol/L) | |
| iPTH | ||||
| Before VitD | 62 pg/mL (6.6 pmol/L) | 29 pg/mL (3.1 pmol/L) | 51 pg/mL (5.4 pmol/L) | ≥19 yrs: |
| After VitD | 41 pg/mL (4.4 pmol/L) | 30 pg/mL (3.2 pmol/L) | 54 pg/mL (5.7 pmol/L) | 14-64 pg/mL (1.5-6.8 pmol/L) |
| iFGF23 | ||||
| Before VitD | 50.4 pg/mL) | 59.9 pg/mL) | 57.1 pg/mL) | 18.6-59.8 pg/mL |
| After VitD | 60.5 pg/mL) | 67.6 pg/mL) | 62.6 pg/mL) | |
| ßCTX | Males: 30-39 yrs (70-780 pg/mL) | |||
| Before VitD | 425 pg/mL | 189 pg/mL | 365 pg/mL | 40-49 yrs (60-700 pg/mL) |
| After VitD | 578 pg/mL | 182 pg/mL | 317 pg/mL | 50-68 yrs (87-345 pg/mL) |
| P1NP | Males: | |||
| Before VitD | 32 mcg/L | 23 mcg/L | 40 mcg/L | 23-60 yrs (30-110 mcg/L) |
| After VitD | 31 mcg/L | 25 mcg/L | 35 mcg/L | > 60 yrs (not stablished) |
Abbreviations: 1,25(OH)2D, 1,25-dihydroxyvitamin D; 24,25(OH)2D, 24,25-dihydroxyvitamin D; 25(OH)D, 25-hydroxyvitamin D; βCTX, type I collagen C-terminal telopeptide; iFGF23, fibroblast growth factor 23; iPTH, intact parathyroid hormone; P1NP, procollagen type 1 amino-terminal propeptide-1; PTH, parathyroid hormone; VitD, vitamin D.
aThe Endocrine Society's proposed cutoffs to define VitD status.
| . | Patient #1 . | Patient #2 . | Patient #3 . | Reference ranges . |
|---|---|---|---|---|
| 25(OH)D | aDeficiency: ≤ 20 (≤ 50 nmol/L) | |||
| Before VitD | 11.7 ng/mL (29 nmol/L) | 10.8 ng/mL (27 nmol/L) | 12.3 (30.7 nmol/L) | Insufficiency: 21-29 (52-72 nmol/L) |
| After VitD | 31.7 (79.1 nmol/L) | 31.8 (79.4 nmol/L) | 33.8 (84.4 nmol/L) | Sufficiency: ≥ 30 (75 nmol/L) |
| 1,25(OH)2D | ||||
| Before VitD | 51 pg/mL (127 pmol/L) | 33 pg/mL (82 pmol/L) | 19 pg/mL (47 pmol/L) | Adults: |
| After VitD | 34 (85 pmol/L) | 29 (72 pmol/L) | 22 (55 pmol/L) | 18-72 pg/mL (45-180 pmol/L) |
| 24,25(OH)2D | ||||
| Before VitD | 0.5 ng/mL (1.3 nmol/L) | 0.8 ng/mL (2 nmol/L) | 0.9 ng/mL (2.3 nmol/L) | ̶ |
| After VitD | 2.9 ng/mL (7.2 nmol/L) | 2.8 ng/mL (7 nmol/L) | 4.1 ng/mL (10.2 nmol/L) | |
| Calcium | ||||
| Before VitD | 9.3 mg/dL (2.32 mmol/L) | 9.6 mg/dL (2.395 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | Males ≥ 20 yrs: |
| After VitD | 9.1 (2.27 mmol/L) | 9.4 mg/dL (2.345 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | 8.6-10.3 mg/dL (2.2-2.6 mmol/L) |
| Phosphorus | ||||
| Before VitD | 3.1 (1 mmol/L) | 3.3 (1.1 mmol/L) | 4.2 (1.36 mmol/L) | 2.5-4.5 mg/dL (0.8-1.5 mmol/L) |
| After VitD | 3.2 (1 mmol/L) | 4 (1.3 mmol/L) | 4.4 (1.42 mmol/L) | |
| iPTH | ||||
| Before VitD | 62 pg/mL (6.6 pmol/L) | 29 pg/mL (3.1 pmol/L) | 51 pg/mL (5.4 pmol/L) | ≥19 yrs: |
| After VitD | 41 pg/mL (4.4 pmol/L) | 30 pg/mL (3.2 pmol/L) | 54 pg/mL (5.7 pmol/L) | 14-64 pg/mL (1.5-6.8 pmol/L) |
| iFGF23 | ||||
| Before VitD | 50.4 pg/mL) | 59.9 pg/mL) | 57.1 pg/mL) | 18.6-59.8 pg/mL |
| After VitD | 60.5 pg/mL) | 67.6 pg/mL) | 62.6 pg/mL) | |
| ßCTX | Males: 30-39 yrs (70-780 pg/mL) | |||
| Before VitD | 425 pg/mL | 189 pg/mL | 365 pg/mL | 40-49 yrs (60-700 pg/mL) |
| After VitD | 578 pg/mL | 182 pg/mL | 317 pg/mL | 50-68 yrs (87-345 pg/mL) |
| P1NP | Males: | |||
| Before VitD | 32 mcg/L | 23 mcg/L | 40 mcg/L | 23-60 yrs (30-110 mcg/L) |
| After VitD | 31 mcg/L | 25 mcg/L | 35 mcg/L | > 60 yrs (not stablished) |
| . | Patient #1 . | Patient #2 . | Patient #3 . | Reference ranges . |
|---|---|---|---|---|
| 25(OH)D | aDeficiency: ≤ 20 (≤ 50 nmol/L) | |||
| Before VitD | 11.7 ng/mL (29 nmol/L) | 10.8 ng/mL (27 nmol/L) | 12.3 (30.7 nmol/L) | Insufficiency: 21-29 (52-72 nmol/L) |
| After VitD | 31.7 (79.1 nmol/L) | 31.8 (79.4 nmol/L) | 33.8 (84.4 nmol/L) | Sufficiency: ≥ 30 (75 nmol/L) |
| 1,25(OH)2D | ||||
| Before VitD | 51 pg/mL (127 pmol/L) | 33 pg/mL (82 pmol/L) | 19 pg/mL (47 pmol/L) | Adults: |
| After VitD | 34 (85 pmol/L) | 29 (72 pmol/L) | 22 (55 pmol/L) | 18-72 pg/mL (45-180 pmol/L) |
| 24,25(OH)2D | ||||
| Before VitD | 0.5 ng/mL (1.3 nmol/L) | 0.8 ng/mL (2 nmol/L) | 0.9 ng/mL (2.3 nmol/L) | ̶ |
| After VitD | 2.9 ng/mL (7.2 nmol/L) | 2.8 ng/mL (7 nmol/L) | 4.1 ng/mL (10.2 nmol/L) | |
| Calcium | ||||
| Before VitD | 9.3 mg/dL (2.32 mmol/L) | 9.6 mg/dL (2.395 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | Males ≥ 20 yrs: |
| After VitD | 9.1 (2.27 mmol/L) | 9.4 mg/dL (2.345 mmol/L) | 9.7 mg/dL (2.4 mmol/L) | 8.6-10.3 mg/dL (2.2-2.6 mmol/L) |
| Phosphorus | ||||
| Before VitD | 3.1 (1 mmol/L) | 3.3 (1.1 mmol/L) | 4.2 (1.36 mmol/L) | 2.5-4.5 mg/dL (0.8-1.5 mmol/L) |
| After VitD | 3.2 (1 mmol/L) | 4 (1.3 mmol/L) | 4.4 (1.42 mmol/L) | |
| iPTH | ||||
| Before VitD | 62 pg/mL (6.6 pmol/L) | 29 pg/mL (3.1 pmol/L) | 51 pg/mL (5.4 pmol/L) | ≥19 yrs: |
| After VitD | 41 pg/mL (4.4 pmol/L) | 30 pg/mL (3.2 pmol/L) | 54 pg/mL (5.7 pmol/L) | 14-64 pg/mL (1.5-6.8 pmol/L) |
| iFGF23 | ||||
| Before VitD | 50.4 pg/mL) | 59.9 pg/mL) | 57.1 pg/mL) | 18.6-59.8 pg/mL |
| After VitD | 60.5 pg/mL) | 67.6 pg/mL) | 62.6 pg/mL) | |
| ßCTX | Males: 30-39 yrs (70-780 pg/mL) | |||
| Before VitD | 425 pg/mL | 189 pg/mL | 365 pg/mL | 40-49 yrs (60-700 pg/mL) |
| After VitD | 578 pg/mL | 182 pg/mL | 317 pg/mL | 50-68 yrs (87-345 pg/mL) |
| P1NP | Males: | |||
| Before VitD | 32 mcg/L | 23 mcg/L | 40 mcg/L | 23-60 yrs (30-110 mcg/L) |
| After VitD | 31 mcg/L | 25 mcg/L | 35 mcg/L | > 60 yrs (not stablished) |
Abbreviations: 1,25(OH)2D, 1,25-dihydroxyvitamin D; 24,25(OH)2D, 24,25-dihydroxyvitamin D; 25(OH)D, 25-hydroxyvitamin D; βCTX, type I collagen C-terminal telopeptide; iFGF23, fibroblast growth factor 23; iPTH, intact parathyroid hormone; P1NP, procollagen type 1 amino-terminal propeptide-1; PTH, parathyroid hormone; VitD, vitamin D.
aThe Endocrine Society's proposed cutoffs to define VitD status.
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