Identification results of rare Jurkat cells among 293 T cells with artificially created batch effects: average F1 score over 10 independent runs.
Nb. rare . | Batch type . | scCross . | MNN . | Seurat v3 . | Scanorama . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | |||
20 | Global | 0.95 | 0.79 | 0.83 | 0.14 | 0.71 | 1.00 | 0.10 | 0.63 | 0.22 | 0.53 |
20 | Gene-specific | 0.97 | 0.98 | 0.46 | 0.23 | 0.52 | 0.47 | 0.16 | 0.84 | 0.43 | 0.51 |
20 | Value-specific | 0.96 | 0.98 | 0.87 | 0.07 | 0.16 | 0.31 | 1.00 | 0.35 | 0.66 | 0.39 |
12 | Global | 0.92 | 0.74 | 0.22 | 0.07 | 0.63 | 0.68 | 0.06 | 0.37 | 0.05 | 0.14 |
12 | Gene-specific | 0.90 | 0.72 | 0.32 | 0.21 | 0.47 | 0.34 | 0.08 | 0.46 | 0.10 | 0.26 |
12 | Value-specific | 0.92 | 0.82 | 0.81 | 0.05 | 0.12 | 0.47 | 0.95 | 0.37 | 0.08 | 0.14 |
6 | Global | 0.92 | 0.50 | 0.07 | 0.03 | 0.55 | 0.59 | 0.09 | 0.39 | 0.12 | 0.03 |
6 | Gene-specific | 0.92 | 0.56 | 0.14 | 0.06 | 0.60 | 0.62 | 0.09 | 0.23 | 0.04 | 0.05 |
6 | Value-specific | 0.93 | 0.80 | 0.26 | 0.02 | 0.60 | 0.59 | 0.20 | 0.35 | 0.08 | 0.05 |
Nb. rare . | Batch type . | scCross . | MNN . | Seurat v3 . | Scanorama . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | |||
20 | Global | 0.95 | 0.79 | 0.83 | 0.14 | 0.71 | 1.00 | 0.10 | 0.63 | 0.22 | 0.53 |
20 | Gene-specific | 0.97 | 0.98 | 0.46 | 0.23 | 0.52 | 0.47 | 0.16 | 0.84 | 0.43 | 0.51 |
20 | Value-specific | 0.96 | 0.98 | 0.87 | 0.07 | 0.16 | 0.31 | 1.00 | 0.35 | 0.66 | 0.39 |
12 | Global | 0.92 | 0.74 | 0.22 | 0.07 | 0.63 | 0.68 | 0.06 | 0.37 | 0.05 | 0.14 |
12 | Gene-specific | 0.90 | 0.72 | 0.32 | 0.21 | 0.47 | 0.34 | 0.08 | 0.46 | 0.10 | 0.26 |
12 | Value-specific | 0.92 | 0.82 | 0.81 | 0.05 | 0.12 | 0.47 | 0.95 | 0.37 | 0.08 | 0.14 |
6 | Global | 0.92 | 0.50 | 0.07 | 0.03 | 0.55 | 0.59 | 0.09 | 0.39 | 0.12 | 0.03 |
6 | Gene-specific | 0.92 | 0.56 | 0.14 | 0.06 | 0.60 | 0.62 | 0.09 | 0.23 | 0.04 | 0.05 |
6 | Value-specific | 0.93 | 0.80 | 0.26 | 0.02 | 0.60 | 0.59 | 0.20 | 0.35 | 0.08 | 0.05 |
Note: Bold results indicate which method outperforms the others for each experiment according to a paired t-test with significance threshold of 0.05 (multiple bold values for the same experiment indicates there is no significant difference between them).
Identification results of rare Jurkat cells among 293 T cells with artificially created batch effects: average F1 score over 10 independent runs.
Nb. rare . | Batch type . | scCross . | MNN . | Seurat v3 . | Scanorama . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | |||
20 | Global | 0.95 | 0.79 | 0.83 | 0.14 | 0.71 | 1.00 | 0.10 | 0.63 | 0.22 | 0.53 |
20 | Gene-specific | 0.97 | 0.98 | 0.46 | 0.23 | 0.52 | 0.47 | 0.16 | 0.84 | 0.43 | 0.51 |
20 | Value-specific | 0.96 | 0.98 | 0.87 | 0.07 | 0.16 | 0.31 | 1.00 | 0.35 | 0.66 | 0.39 |
12 | Global | 0.92 | 0.74 | 0.22 | 0.07 | 0.63 | 0.68 | 0.06 | 0.37 | 0.05 | 0.14 |
12 | Gene-specific | 0.90 | 0.72 | 0.32 | 0.21 | 0.47 | 0.34 | 0.08 | 0.46 | 0.10 | 0.26 |
12 | Value-specific | 0.92 | 0.82 | 0.81 | 0.05 | 0.12 | 0.47 | 0.95 | 0.37 | 0.08 | 0.14 |
6 | Global | 0.92 | 0.50 | 0.07 | 0.03 | 0.55 | 0.59 | 0.09 | 0.39 | 0.12 | 0.03 |
6 | Gene-specific | 0.92 | 0.56 | 0.14 | 0.06 | 0.60 | 0.62 | 0.09 | 0.23 | 0.04 | 0.05 |
6 | Value-specific | 0.93 | 0.80 | 0.26 | 0.02 | 0.60 | 0.59 | 0.20 | 0.35 | 0.08 | 0.05 |
Nb. rare . | Batch type . | scCross . | MNN . | Seurat v3 . | Scanorama . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | RaceID3 . | GiniClust3 . | scAIDE . | |||
20 | Global | 0.95 | 0.79 | 0.83 | 0.14 | 0.71 | 1.00 | 0.10 | 0.63 | 0.22 | 0.53 |
20 | Gene-specific | 0.97 | 0.98 | 0.46 | 0.23 | 0.52 | 0.47 | 0.16 | 0.84 | 0.43 | 0.51 |
20 | Value-specific | 0.96 | 0.98 | 0.87 | 0.07 | 0.16 | 0.31 | 1.00 | 0.35 | 0.66 | 0.39 |
12 | Global | 0.92 | 0.74 | 0.22 | 0.07 | 0.63 | 0.68 | 0.06 | 0.37 | 0.05 | 0.14 |
12 | Gene-specific | 0.90 | 0.72 | 0.32 | 0.21 | 0.47 | 0.34 | 0.08 | 0.46 | 0.10 | 0.26 |
12 | Value-specific | 0.92 | 0.82 | 0.81 | 0.05 | 0.12 | 0.47 | 0.95 | 0.37 | 0.08 | 0.14 |
6 | Global | 0.92 | 0.50 | 0.07 | 0.03 | 0.55 | 0.59 | 0.09 | 0.39 | 0.12 | 0.03 |
6 | Gene-specific | 0.92 | 0.56 | 0.14 | 0.06 | 0.60 | 0.62 | 0.09 | 0.23 | 0.04 | 0.05 |
6 | Value-specific | 0.93 | 0.80 | 0.26 | 0.02 | 0.60 | 0.59 | 0.20 | 0.35 | 0.08 | 0.05 |
Note: Bold results indicate which method outperforms the others for each experiment according to a paired t-test with significance threshold of 0.05 (multiple bold values for the same experiment indicates there is no significant difference between them).
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