Trends in clinical risk and patterns of myocardial perfusion scintigraphy in women, over the last 20 years from 2000 to 2020
| . | 2000–04 . | 2004–09 . | 2009–14 . | 2014–19 . | 2019–20 . | P-value . | P-value trend . |
|---|---|---|---|---|---|---|---|
| Typical angina | 305 (27) | 809 (54) | 870 (50) | 885 (47) | 131 (49) | <0.001 | <0.001 |
| Dyspnoea | 749 (66) | 1161 (77) | 1432 (83) | 1583 (84) | 185 (70) | <0.001 | <0.001 |
| Family history | 635 (56) | 908 (61) | 850 (49) | 908 (48) | 128 (48) | <0.001 | <0.001 |
| Smoking history | 448 (40) | 666 (44) | 613 (35) | 810 (43) | 91 (34) | <0.001 | |
| Diabetes | 531 (47) | 831 (55) | 848 (49) | 917 (49) | 117 (44) | <0.001 | 0.857 |
| Hypertension | 613 (54) | 989 (66) | 1125 (65) | 1265 (67) | 142 (54) | <0.001 | <0.001 |
| Hypercholesterolaemia | 606 (53) | 873 (58) | 1002 (58) | 1055 (56) | 149 (56) | 0.13 | 0.605 |
| Previous revascularization | 201 (18) | 261 (17) | 302 (17) | 320 (17) | 49 (18) | 0.976 | 0.617 |
| EF rest | 59 (48.2–65) | 61 (51–67) | 68 (60–74) | 70 (62–76) | 72 (65–75) | <0.001 | <0.001 |
| EF stress | 58 (46–65) | 60 (50–68) | 68 (60–74) | 69 (62–76) | 71 (64–78) | <0.001 | <0.001 |
| EDV rest | 101 (82.8–138) | 100 (77–132) | 75 (61–94) | 71 (59–87) | 65 (55–81) | <0.001 | <0.001 |
| EDV stress | 102 (82–140) | 94 (77–125) | 73 (60–91) | 69 (56–84) | 62 (52–78) | <0.001 | <0.001 |
| ESV rest | 42 (30–68) | 39 (26–65) | 24 (17–37) | 22 (15–32) | 18 (13–28) | <0.001 | <0.001 |
| ESV stress | 43 (29–73) | 37 (25–63) | 23 (17–35) | 21 (14–31) | 17 (13–30) | <0.001 | <0.001 |
| SSS | 8 (4–12) | 6 (3–12) | 4 (1–8) | 4 (2–7) | 3 (2–5) | <0.001 | <0.001 |
| SRS | 2 (0–5) | 1 (0–4) | 0 (0–3) | 0 (0–2) | 0 (0–1) | <0.001 | <0.001 |
| SDS | 4 (2–7) | 4 (2–7) | 3 (1–5) | 3 (1–5) | 3 (1.5–5) | <0.001 | <0.001 |
| . | 2000–04 . | 2004–09 . | 2009–14 . | 2014–19 . | 2019–20 . | P-value . | P-value trend . |
|---|---|---|---|---|---|---|---|
| Typical angina | 305 (27) | 809 (54) | 870 (50) | 885 (47) | 131 (49) | <0.001 | <0.001 |
| Dyspnoea | 749 (66) | 1161 (77) | 1432 (83) | 1583 (84) | 185 (70) | <0.001 | <0.001 |
| Family history | 635 (56) | 908 (61) | 850 (49) | 908 (48) | 128 (48) | <0.001 | <0.001 |
| Smoking history | 448 (40) | 666 (44) | 613 (35) | 810 (43) | 91 (34) | <0.001 | |
| Diabetes | 531 (47) | 831 (55) | 848 (49) | 917 (49) | 117 (44) | <0.001 | 0.857 |
| Hypertension | 613 (54) | 989 (66) | 1125 (65) | 1265 (67) | 142 (54) | <0.001 | <0.001 |
| Hypercholesterolaemia | 606 (53) | 873 (58) | 1002 (58) | 1055 (56) | 149 (56) | 0.13 | 0.605 |
| Previous revascularization | 201 (18) | 261 (17) | 302 (17) | 320 (17) | 49 (18) | 0.976 | 0.617 |
| EF rest | 59 (48.2–65) | 61 (51–67) | 68 (60–74) | 70 (62–76) | 72 (65–75) | <0.001 | <0.001 |
| EF stress | 58 (46–65) | 60 (50–68) | 68 (60–74) | 69 (62–76) | 71 (64–78) | <0.001 | <0.001 |
| EDV rest | 101 (82.8–138) | 100 (77–132) | 75 (61–94) | 71 (59–87) | 65 (55–81) | <0.001 | <0.001 |
| EDV stress | 102 (82–140) | 94 (77–125) | 73 (60–91) | 69 (56–84) | 62 (52–78) | <0.001 | <0.001 |
| ESV rest | 42 (30–68) | 39 (26–65) | 24 (17–37) | 22 (15–32) | 18 (13–28) | <0.001 | <0.001 |
| ESV stress | 43 (29–73) | 37 (25–63) | 23 (17–35) | 21 (14–31) | 17 (13–30) | <0.001 | <0.001 |
| SSS | 8 (4–12) | 6 (3–12) | 4 (1–8) | 4 (2–7) | 3 (2–5) | <0.001 | <0.001 |
| SRS | 2 (0–5) | 1 (0–4) | 0 (0–3) | 0 (0–2) | 0 (0–1) | <0.001 | <0.001 |
| SDS | 4 (2–7) | 4 (2–7) | 3 (1–5) | 3 (1–5) | 3 (1.5–5) | <0.001 | <0.001 |
EF, ejection fraction; EDV, end diastolic volume; ESV, end systolic volume; SSS, summed stress score; SRS, summed rest score; SDS, summed difference score.
Trends in clinical risk and patterns of myocardial perfusion scintigraphy in women, over the last 20 years from 2000 to 2020
| . | 2000–04 . | 2004–09 . | 2009–14 . | 2014–19 . | 2019–20 . | P-value . | P-value trend . |
|---|---|---|---|---|---|---|---|
| Typical angina | 305 (27) | 809 (54) | 870 (50) | 885 (47) | 131 (49) | <0.001 | <0.001 |
| Dyspnoea | 749 (66) | 1161 (77) | 1432 (83) | 1583 (84) | 185 (70) | <0.001 | <0.001 |
| Family history | 635 (56) | 908 (61) | 850 (49) | 908 (48) | 128 (48) | <0.001 | <0.001 |
| Smoking history | 448 (40) | 666 (44) | 613 (35) | 810 (43) | 91 (34) | <0.001 | |
| Diabetes | 531 (47) | 831 (55) | 848 (49) | 917 (49) | 117 (44) | <0.001 | 0.857 |
| Hypertension | 613 (54) | 989 (66) | 1125 (65) | 1265 (67) | 142 (54) | <0.001 | <0.001 |
| Hypercholesterolaemia | 606 (53) | 873 (58) | 1002 (58) | 1055 (56) | 149 (56) | 0.13 | 0.605 |
| Previous revascularization | 201 (18) | 261 (17) | 302 (17) | 320 (17) | 49 (18) | 0.976 | 0.617 |
| EF rest | 59 (48.2–65) | 61 (51–67) | 68 (60–74) | 70 (62–76) | 72 (65–75) | <0.001 | <0.001 |
| EF stress | 58 (46–65) | 60 (50–68) | 68 (60–74) | 69 (62–76) | 71 (64–78) | <0.001 | <0.001 |
| EDV rest | 101 (82.8–138) | 100 (77–132) | 75 (61–94) | 71 (59–87) | 65 (55–81) | <0.001 | <0.001 |
| EDV stress | 102 (82–140) | 94 (77–125) | 73 (60–91) | 69 (56–84) | 62 (52–78) | <0.001 | <0.001 |
| ESV rest | 42 (30–68) | 39 (26–65) | 24 (17–37) | 22 (15–32) | 18 (13–28) | <0.001 | <0.001 |
| ESV stress | 43 (29–73) | 37 (25–63) | 23 (17–35) | 21 (14–31) | 17 (13–30) | <0.001 | <0.001 |
| SSS | 8 (4–12) | 6 (3–12) | 4 (1–8) | 4 (2–7) | 3 (2–5) | <0.001 | <0.001 |
| SRS | 2 (0–5) | 1 (0–4) | 0 (0–3) | 0 (0–2) | 0 (0–1) | <0.001 | <0.001 |
| SDS | 4 (2–7) | 4 (2–7) | 3 (1–5) | 3 (1–5) | 3 (1.5–5) | <0.001 | <0.001 |
| . | 2000–04 . | 2004–09 . | 2009–14 . | 2014–19 . | 2019–20 . | P-value . | P-value trend . |
|---|---|---|---|---|---|---|---|
| Typical angina | 305 (27) | 809 (54) | 870 (50) | 885 (47) | 131 (49) | <0.001 | <0.001 |
| Dyspnoea | 749 (66) | 1161 (77) | 1432 (83) | 1583 (84) | 185 (70) | <0.001 | <0.001 |
| Family history | 635 (56) | 908 (61) | 850 (49) | 908 (48) | 128 (48) | <0.001 | <0.001 |
| Smoking history | 448 (40) | 666 (44) | 613 (35) | 810 (43) | 91 (34) | <0.001 | |
| Diabetes | 531 (47) | 831 (55) | 848 (49) | 917 (49) | 117 (44) | <0.001 | 0.857 |
| Hypertension | 613 (54) | 989 (66) | 1125 (65) | 1265 (67) | 142 (54) | <0.001 | <0.001 |
| Hypercholesterolaemia | 606 (53) | 873 (58) | 1002 (58) | 1055 (56) | 149 (56) | 0.13 | 0.605 |
| Previous revascularization | 201 (18) | 261 (17) | 302 (17) | 320 (17) | 49 (18) | 0.976 | 0.617 |
| EF rest | 59 (48.2–65) | 61 (51–67) | 68 (60–74) | 70 (62–76) | 72 (65–75) | <0.001 | <0.001 |
| EF stress | 58 (46–65) | 60 (50–68) | 68 (60–74) | 69 (62–76) | 71 (64–78) | <0.001 | <0.001 |
| EDV rest | 101 (82.8–138) | 100 (77–132) | 75 (61–94) | 71 (59–87) | 65 (55–81) | <0.001 | <0.001 |
| EDV stress | 102 (82–140) | 94 (77–125) | 73 (60–91) | 69 (56–84) | 62 (52–78) | <0.001 | <0.001 |
| ESV rest | 42 (30–68) | 39 (26–65) | 24 (17–37) | 22 (15–32) | 18 (13–28) | <0.001 | <0.001 |
| ESV stress | 43 (29–73) | 37 (25–63) | 23 (17–35) | 21 (14–31) | 17 (13–30) | <0.001 | <0.001 |
| SSS | 8 (4–12) | 6 (3–12) | 4 (1–8) | 4 (2–7) | 3 (2–5) | <0.001 | <0.001 |
| SRS | 2 (0–5) | 1 (0–4) | 0 (0–3) | 0 (0–2) | 0 (0–1) | <0.001 | <0.001 |
| SDS | 4 (2–7) | 4 (2–7) | 3 (1–5) | 3 (1–5) | 3 (1.5–5) | <0.001 | <0.001 |
EF, ejection fraction; EDV, end diastolic volume; ESV, end systolic volume; SSS, summed stress score; SRS, summed rest score; SDS, summed difference score.
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