Association between the use of sodium-glucose cotransporter-2 inhibitors and the HR of AF
| Exposure . | Events, No. . | Person-years . | Incidence rate per 1,000 person-years (95% CI) . | Crude HR (95% CI) . | Adjusted HR (95% CI) . |
|---|---|---|---|---|---|
| Second-line to third-line antidiabetic drugs | 1504 | 149,798 | 10.04 (9.54–10.56) | Reference | Reference |
| Sodium-glucose cotransporter-2 inhibitors | 287 | 58,673 | 4.89 (4.36–5.49) | 0.48 (0.42–0.54) | 0.77 (0.68–0.88) |
| Exposure . | Events, No. . | Person-years . | Incidence rate per 1,000 person-years (95% CI) . | Crude HR (95% CI) . | Adjusted HR (95% CI) . |
|---|---|---|---|---|---|
| Second-line to third-line antidiabetic drugs | 1504 | 149,798 | 10.04 (9.54–10.56) | Reference | Reference |
| Sodium-glucose cotransporter-2 inhibitors | 287 | 58,673 | 4.89 (4.36–5.49) | 0.48 (0.42–0.54) | 0.77 (0.68–0.88) |
CI, confidence interval; HR, hazard ratio. Adjusted for age, sex, ischaemic heart disease (including acute myocardial infarction), heart failure, peripheral artery disease, hypertension, stroke, kidney function, duration of diabetes, smoking, HbA1C, body mass index, ICD/pacemaker, and number of cardiovascular drugs
Association between the use of sodium-glucose cotransporter-2 inhibitors and the HR of AF
| Exposure . | Events, No. . | Person-years . | Incidence rate per 1,000 person-years (95% CI) . | Crude HR (95% CI) . | Adjusted HR (95% CI) . |
|---|---|---|---|---|---|
| Second-line to third-line antidiabetic drugs | 1504 | 149,798 | 10.04 (9.54–10.56) | Reference | Reference |
| Sodium-glucose cotransporter-2 inhibitors | 287 | 58,673 | 4.89 (4.36–5.49) | 0.48 (0.42–0.54) | 0.77 (0.68–0.88) |
| Exposure . | Events, No. . | Person-years . | Incidence rate per 1,000 person-years (95% CI) . | Crude HR (95% CI) . | Adjusted HR (95% CI) . |
|---|---|---|---|---|---|
| Second-line to third-line antidiabetic drugs | 1504 | 149,798 | 10.04 (9.54–10.56) | Reference | Reference |
| Sodium-glucose cotransporter-2 inhibitors | 287 | 58,673 | 4.89 (4.36–5.49) | 0.48 (0.42–0.54) | 0.77 (0.68–0.88) |
CI, confidence interval; HR, hazard ratio. Adjusted for age, sex, ischaemic heart disease (including acute myocardial infarction), heart failure, peripheral artery disease, hypertension, stroke, kidney function, duration of diabetes, smoking, HbA1C, body mass index, ICD/pacemaker, and number of cardiovascular drugs
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