Auxological data and hormonal results in males with CPP divided according to MRI findings at the time of diagnosis
| Parameter . | Group 1 N°167, mean ± SD (range) . | Group 2 N° 15, mean ± SD (range) . | Group 3 N° 11, mean ± SD (range) . | |||
|---|---|---|---|---|---|---|
| Age at diagnosis, years | N° 167 | 8.9 ± 1.1(4–11) | N° 15 | 9.4 ± 0.7 (8.4–10.6) | N° 11 | 7.5 ± 2.8 (1.1–10.4)* |
| Age at onset symptoms, years | 160 | 8.2 ± 0.8 | 15 | 8.5 ± 0.4 | 11 | 6.5 ± 2.8* |
| Height SDS | 158 | 0.8 ± 1.2 | 12 | 0.9 ± 1.4 | 10 | 1.3 ± 1.7 |
| BMI SDS | 158 | 0.7 ± 1.9 | 12 | 0.9 ± 0.8 | 10 | 1.3 ± 1.1 |
| BA/CA ratio | 153 | 1.2 ± 0.1 | 13 | 1.2 ± 0.2 | 9 | 1.4 ± 1.2 (0.9–2.8) |
| Testicular Volume, ml | 167 | 6.9 ± 3.1 | 15 | 7.4 ± 3.4 | 11 | 8.6 ± 3.8 |
| Basal LH, IU/L | 167 | 1.5 ± 1.7 | 15 | 1.5 ± 1.4 | 11 | 3.7 ± 3.6* |
| Peak LH at GnRH test, IU/L | 167 | 15.3 ± 0.3 | 15 | 16 ± 6.8 | 11 | 16.1 ± 6.4 |
| Basal LH > 0.3 IU/L (%) | 167 | 76.7% | 15 | 91.6% | 11 | 100% |
| Peak LH > 5 IU/L (%) | 167 | 91.4% | 15 | 100% | 11 | 100% |
| Pubertal testosterone levels (%) | 150 | 71.0% | 12 | 75.0% | 9 | 100% |
| Parameter . | Group 1 N°167, mean ± SD (range) . | Group 2 N° 15, mean ± SD (range) . | Group 3 N° 11, mean ± SD (range) . | |||
|---|---|---|---|---|---|---|
| Age at diagnosis, years | N° 167 | 8.9 ± 1.1(4–11) | N° 15 | 9.4 ± 0.7 (8.4–10.6) | N° 11 | 7.5 ± 2.8 (1.1–10.4)* |
| Age at onset symptoms, years | 160 | 8.2 ± 0.8 | 15 | 8.5 ± 0.4 | 11 | 6.5 ± 2.8* |
| Height SDS | 158 | 0.8 ± 1.2 | 12 | 0.9 ± 1.4 | 10 | 1.3 ± 1.7 |
| BMI SDS | 158 | 0.7 ± 1.9 | 12 | 0.9 ± 0.8 | 10 | 1.3 ± 1.1 |
| BA/CA ratio | 153 | 1.2 ± 0.1 | 13 | 1.2 ± 0.2 | 9 | 1.4 ± 1.2 (0.9–2.8) |
| Testicular Volume, ml | 167 | 6.9 ± 3.1 | 15 | 7.4 ± 3.4 | 11 | 8.6 ± 3.8 |
| Basal LH, IU/L | 167 | 1.5 ± 1.7 | 15 | 1.5 ± 1.4 | 11 | 3.7 ± 3.6* |
| Peak LH at GnRH test, IU/L | 167 | 15.3 ± 0.3 | 15 | 16 ± 6.8 | 11 | 16.1 ± 6.4 |
| Basal LH > 0.3 IU/L (%) | 167 | 76.7% | 15 | 91.6% | 11 | 100% |
| Peak LH > 5 IU/L (%) | 167 | 91.4% | 15 | 100% | 11 | 100% |
| Pubertal testosterone levels (%) | 150 | 71.0% | 12 | 75.0% | 9 | 100% |
*P < .05 vs groups 1 and 2.
Auxological data and hormonal results in males with CPP divided according to MRI findings at the time of diagnosis
| Parameter . | Group 1 N°167, mean ± SD (range) . | Group 2 N° 15, mean ± SD (range) . | Group 3 N° 11, mean ± SD (range) . | |||
|---|---|---|---|---|---|---|
| Age at diagnosis, years | N° 167 | 8.9 ± 1.1(4–11) | N° 15 | 9.4 ± 0.7 (8.4–10.6) | N° 11 | 7.5 ± 2.8 (1.1–10.4)* |
| Age at onset symptoms, years | 160 | 8.2 ± 0.8 | 15 | 8.5 ± 0.4 | 11 | 6.5 ± 2.8* |
| Height SDS | 158 | 0.8 ± 1.2 | 12 | 0.9 ± 1.4 | 10 | 1.3 ± 1.7 |
| BMI SDS | 158 | 0.7 ± 1.9 | 12 | 0.9 ± 0.8 | 10 | 1.3 ± 1.1 |
| BA/CA ratio | 153 | 1.2 ± 0.1 | 13 | 1.2 ± 0.2 | 9 | 1.4 ± 1.2 (0.9–2.8) |
| Testicular Volume, ml | 167 | 6.9 ± 3.1 | 15 | 7.4 ± 3.4 | 11 | 8.6 ± 3.8 |
| Basal LH, IU/L | 167 | 1.5 ± 1.7 | 15 | 1.5 ± 1.4 | 11 | 3.7 ± 3.6* |
| Peak LH at GnRH test, IU/L | 167 | 15.3 ± 0.3 | 15 | 16 ± 6.8 | 11 | 16.1 ± 6.4 |
| Basal LH > 0.3 IU/L (%) | 167 | 76.7% | 15 | 91.6% | 11 | 100% |
| Peak LH > 5 IU/L (%) | 167 | 91.4% | 15 | 100% | 11 | 100% |
| Pubertal testosterone levels (%) | 150 | 71.0% | 12 | 75.0% | 9 | 100% |
| Parameter . | Group 1 N°167, mean ± SD (range) . | Group 2 N° 15, mean ± SD (range) . | Group 3 N° 11, mean ± SD (range) . | |||
|---|---|---|---|---|---|---|
| Age at diagnosis, years | N° 167 | 8.9 ± 1.1(4–11) | N° 15 | 9.4 ± 0.7 (8.4–10.6) | N° 11 | 7.5 ± 2.8 (1.1–10.4)* |
| Age at onset symptoms, years | 160 | 8.2 ± 0.8 | 15 | 8.5 ± 0.4 | 11 | 6.5 ± 2.8* |
| Height SDS | 158 | 0.8 ± 1.2 | 12 | 0.9 ± 1.4 | 10 | 1.3 ± 1.7 |
| BMI SDS | 158 | 0.7 ± 1.9 | 12 | 0.9 ± 0.8 | 10 | 1.3 ± 1.1 |
| BA/CA ratio | 153 | 1.2 ± 0.1 | 13 | 1.2 ± 0.2 | 9 | 1.4 ± 1.2 (0.9–2.8) |
| Testicular Volume, ml | 167 | 6.9 ± 3.1 | 15 | 7.4 ± 3.4 | 11 | 8.6 ± 3.8 |
| Basal LH, IU/L | 167 | 1.5 ± 1.7 | 15 | 1.5 ± 1.4 | 11 | 3.7 ± 3.6* |
| Peak LH at GnRH test, IU/L | 167 | 15.3 ± 0.3 | 15 | 16 ± 6.8 | 11 | 16.1 ± 6.4 |
| Basal LH > 0.3 IU/L (%) | 167 | 76.7% | 15 | 91.6% | 11 | 100% |
| Peak LH > 5 IU/L (%) | 167 | 91.4% | 15 | 100% | 11 | 100% |
| Pubertal testosterone levels (%) | 150 | 71.0% | 12 | 75.0% | 9 | 100% |
*P < .05 vs groups 1 and 2.
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