Presenting mSOFA score among nonelderly patients (ages 18-64 y) admitted to New York University Langone Health (complete-case model) during the peak period of the COVID-19 pandemic (n = 1794), New York, New York, March 1-June 30, 2020.
| Patient characteristic . | Total no. of patients . | mSOFA score . | P value . | |||
|---|---|---|---|---|---|---|
| Overall . | 0-3 . | 4-7 . | >7 . | |||
| (n = 1794) . | (n = 1350; 75.3%) . | (n = 326; 18.2%) . | (n = 118; 6.6%) . | |||
| No. (%) of deaths | 1794 | 194 (11) | 68 (5.0) | 71 (22) | 55 (47) | <.001 |
| Median (IQR) length of stay, d | 1794 | 6 (3-11) | 5 (3-9) | 9 (5-17) | 12 (6-26) | <.001 |
| Median (IQR) nondeath length of stay, d | 1600 | 5 (3-10) | 5 (3-8) | 9 (5-16) | 18 (8-41) | <.001 |
| Type of health-care coverage, no. (%) | 1794 | |||||
| Private | 881 (49) | 674 (50) | 153 (47) | 54 (46) | .5 | |
| Medicare | 188 (10) | 115 (8.5) | 64 (20) | 9 (7.6) | <.001 | |
| Medicaid | 413 (23) | 323 (24) | 67 (21) | 23 (19) | .3 | |
| Uninsured | 312 (17) | 238 (18) | 42 (13) | 32 (27) | .002 | |
| Median (IQR) age, y | 1794 | 52 (42-59) | 51 (41-58) | 56 (47-60) | 54 (46-59) | <.001 |
| Male sex, no. (%) | 1794 | 1173 (65) | 835 (62) | 248 (76) | 90 (76) | <.001 |
| Race and ethnicity, no. (%) | 1794 | .07 | ||||
| Asian or Pacific Islander | 129 (7.2) | 99 (7.3) | 23 (7.1) | 7 (5.9) | .8 | |
| Hispanic | 657 (37) | 508 (38) | 101 (31) | 48 (41) | .052 | |
| Non-Hispanic Black | 315 (18) | 223 (17) | 77 (24) | 15 (13) | .004 | |
| Non-Hispanic White | 490 (27) | 372 (28) | 87 (27) | 31 (26) | >.9 | |
| Other | 203 (11) | 148 (11) | 38 (12) | 17 (14) | .5 | |
| Median (IQR) calendar week of admission | 1794 | 12 (11-14) | 12 (11-14) | 12 (12-14) | 12 (11-13) | .05 |
| Hour of admission, no. (%) | 1794 | |||||
| 12 am-4 am | 160 (8.9) | 114 (8.4) | 35 (11) | 11 (9.3) | .4 | |
| 5 am-9 am | 203 (11) | 152 (11) | 40 (12) | 11 (9.3) | .7 | |
| 10 am-2 pm | 564 (31) | 395 (29) | 121 (37) | 48 (41) | .002 | |
| 3 pm-7 pm | 558 (31) | 448 (33) | 75 (23) | 35 (30) | .002 | |
| 8 pm-11 pm | 309 (17) | 241 (18) | 55 (17) | 13 (11) | .2 | |
| Median (IQR) body mass indexa | 1697 | 30 (26-35) | 30 (26-34) | 29 (26-35) | 30 (26-35) | .5 |
| Preexisting conditions, no. (%) | 1794 | |||||
| Diabetes | 577 (32) | 400 (30) | 132 (40) | 45 (38) | <.001 | |
| Hypertension | 819 (46) | 555 (41) | 198 (61) | 66 (56) | <.001 | |
| Cardiac disease | 332 (19) | 214 (16) | 92 (28) | 26 (22) | <.001 | |
| Peripheral vascular disorder | 125 (7.0) | 76 (5.6) | 40 (12) | 9 (7.6) | <.001 | |
| Pulmonary disease | 389 (22) | 283 (21) | 80 (25) | 26 (22) | .4 | |
| Cancer | 109 (6.1) | 80 (5.9) | 26 (8.0) | 3 (2.5) | .1 | |
| Renal failure | 219 (12) | 91 (6.7) | 106 (33) | 22 (19) | <.001 | |
| Liver disease | 145 (8.1) | 99 (7.3) | 36 (11) | 10 (8.5) | .087 | |
| Coagulation | 158 (8.8) | 98 (7.3) | 45 (14) | 15 (13) | <.001 | |
| Elixhauser AHQR Index score, no. (%) | 1794 | |||||
| <0 | 552 (31) | 445 (33) | 77 (24) | 30 (25) | .002 | |
| 0 | 406 (23) | 343 (25) | 47 (14) | 16 (14) | <.001 | |
| 1-4 | 155 (8.6) | 125 (9.3) | 23 (7.1) | 7 (5.9) | .2 | |
| ≥5 | 681 (38) | 437 (32) | 179 (55) | 65 (55) | <.001 | |
| No. (%) of prior outpatient visits | 1794 | |||||
| 0 | 1130 (63) | 857 (63) | 192 (59) | 81 (69) | .13 | |
| 1-3 | 262 (15) | 206 (15) | 45 (14) | 11 (9.3) | .2 | |
| >3 | 402 (22) | 287 (21) | 89 (27) | 26 (22) | .06 | |
| No. (%) of prior inpatient visits | 1794 | 232 (13) | 162 (12) | 55 (17) | 15 (13) | .06 |
| Median (IQR) distance from hospital, milesb | 1794 | 3.7 (2.0-6.3) | 3.7 (2.0-6.3) | 3.9 (2.3-6.4) | 3.6 (1.8-5.8) | .4 |
| Patient characteristic . | Total no. of patients . | mSOFA score . | P value . | |||
|---|---|---|---|---|---|---|
| Overall . | 0-3 . | 4-7 . | >7 . | |||
| (n = 1794) . | (n = 1350; 75.3%) . | (n = 326; 18.2%) . | (n = 118; 6.6%) . | |||
| No. (%) of deaths | 1794 | 194 (11) | 68 (5.0) | 71 (22) | 55 (47) | <.001 |
| Median (IQR) length of stay, d | 1794 | 6 (3-11) | 5 (3-9) | 9 (5-17) | 12 (6-26) | <.001 |
| Median (IQR) nondeath length of stay, d | 1600 | 5 (3-10) | 5 (3-8) | 9 (5-16) | 18 (8-41) | <.001 |
| Type of health-care coverage, no. (%) | 1794 | |||||
| Private | 881 (49) | 674 (50) | 153 (47) | 54 (46) | .5 | |
| Medicare | 188 (10) | 115 (8.5) | 64 (20) | 9 (7.6) | <.001 | |
| Medicaid | 413 (23) | 323 (24) | 67 (21) | 23 (19) | .3 | |
| Uninsured | 312 (17) | 238 (18) | 42 (13) | 32 (27) | .002 | |
| Median (IQR) age, y | 1794 | 52 (42-59) | 51 (41-58) | 56 (47-60) | 54 (46-59) | <.001 |
| Male sex, no. (%) | 1794 | 1173 (65) | 835 (62) | 248 (76) | 90 (76) | <.001 |
| Race and ethnicity, no. (%) | 1794 | .07 | ||||
| Asian or Pacific Islander | 129 (7.2) | 99 (7.3) | 23 (7.1) | 7 (5.9) | .8 | |
| Hispanic | 657 (37) | 508 (38) | 101 (31) | 48 (41) | .052 | |
| Non-Hispanic Black | 315 (18) | 223 (17) | 77 (24) | 15 (13) | .004 | |
| Non-Hispanic White | 490 (27) | 372 (28) | 87 (27) | 31 (26) | >.9 | |
| Other | 203 (11) | 148 (11) | 38 (12) | 17 (14) | .5 | |
| Median (IQR) calendar week of admission | 1794 | 12 (11-14) | 12 (11-14) | 12 (12-14) | 12 (11-13) | .05 |
| Hour of admission, no. (%) | 1794 | |||||
| 12 am-4 am | 160 (8.9) | 114 (8.4) | 35 (11) | 11 (9.3) | .4 | |
| 5 am-9 am | 203 (11) | 152 (11) | 40 (12) | 11 (9.3) | .7 | |
| 10 am-2 pm | 564 (31) | 395 (29) | 121 (37) | 48 (41) | .002 | |
| 3 pm-7 pm | 558 (31) | 448 (33) | 75 (23) | 35 (30) | .002 | |
| 8 pm-11 pm | 309 (17) | 241 (18) | 55 (17) | 13 (11) | .2 | |
| Median (IQR) body mass indexa | 1697 | 30 (26-35) | 30 (26-34) | 29 (26-35) | 30 (26-35) | .5 |
| Preexisting conditions, no. (%) | 1794 | |||||
| Diabetes | 577 (32) | 400 (30) | 132 (40) | 45 (38) | <.001 | |
| Hypertension | 819 (46) | 555 (41) | 198 (61) | 66 (56) | <.001 | |
| Cardiac disease | 332 (19) | 214 (16) | 92 (28) | 26 (22) | <.001 | |
| Peripheral vascular disorder | 125 (7.0) | 76 (5.6) | 40 (12) | 9 (7.6) | <.001 | |
| Pulmonary disease | 389 (22) | 283 (21) | 80 (25) | 26 (22) | .4 | |
| Cancer | 109 (6.1) | 80 (5.9) | 26 (8.0) | 3 (2.5) | .1 | |
| Renal failure | 219 (12) | 91 (6.7) | 106 (33) | 22 (19) | <.001 | |
| Liver disease | 145 (8.1) | 99 (7.3) | 36 (11) | 10 (8.5) | .087 | |
| Coagulation | 158 (8.8) | 98 (7.3) | 45 (14) | 15 (13) | <.001 | |
| Elixhauser AHQR Index score, no. (%) | 1794 | |||||
| <0 | 552 (31) | 445 (33) | 77 (24) | 30 (25) | .002 | |
| 0 | 406 (23) | 343 (25) | 47 (14) | 16 (14) | <.001 | |
| 1-4 | 155 (8.6) | 125 (9.3) | 23 (7.1) | 7 (5.9) | .2 | |
| ≥5 | 681 (38) | 437 (32) | 179 (55) | 65 (55) | <.001 | |
| No. (%) of prior outpatient visits | 1794 | |||||
| 0 | 1130 (63) | 857 (63) | 192 (59) | 81 (69) | .13 | |
| 1-3 | 262 (15) | 206 (15) | 45 (14) | 11 (9.3) | .2 | |
| >3 | 402 (22) | 287 (21) | 89 (27) | 26 (22) | .06 | |
| No. (%) of prior inpatient visits | 1794 | 232 (13) | 162 (12) | 55 (17) | 15 (13) | .06 |
| Median (IQR) distance from hospital, milesb | 1794 | 3.7 (2.0-6.3) | 3.7 (2.0-6.3) | 3.9 (2.3-6.4) | 3.6 (1.8-5.8) | .4 |
Abbreviations: AHQR, Agency for Healthcare Research and Quality; IQR, interquartile range; mSOFA, modified sequential organ failure assessment.
a Weight (kg)/height (m)2.
b 1 mile = 1.6 km.
Presenting mSOFA score among nonelderly patients (ages 18-64 y) admitted to New York University Langone Health (complete-case model) during the peak period of the COVID-19 pandemic (n = 1794), New York, New York, March 1-June 30, 2020.
| Patient characteristic . | Total no. of patients . | mSOFA score . | P value . | |||
|---|---|---|---|---|---|---|
| Overall . | 0-3 . | 4-7 . | >7 . | |||
| (n = 1794) . | (n = 1350; 75.3%) . | (n = 326; 18.2%) . | (n = 118; 6.6%) . | |||
| No. (%) of deaths | 1794 | 194 (11) | 68 (5.0) | 71 (22) | 55 (47) | <.001 |
| Median (IQR) length of stay, d | 1794 | 6 (3-11) | 5 (3-9) | 9 (5-17) | 12 (6-26) | <.001 |
| Median (IQR) nondeath length of stay, d | 1600 | 5 (3-10) | 5 (3-8) | 9 (5-16) | 18 (8-41) | <.001 |
| Type of health-care coverage, no. (%) | 1794 | |||||
| Private | 881 (49) | 674 (50) | 153 (47) | 54 (46) | .5 | |
| Medicare | 188 (10) | 115 (8.5) | 64 (20) | 9 (7.6) | <.001 | |
| Medicaid | 413 (23) | 323 (24) | 67 (21) | 23 (19) | .3 | |
| Uninsured | 312 (17) | 238 (18) | 42 (13) | 32 (27) | .002 | |
| Median (IQR) age, y | 1794 | 52 (42-59) | 51 (41-58) | 56 (47-60) | 54 (46-59) | <.001 |
| Male sex, no. (%) | 1794 | 1173 (65) | 835 (62) | 248 (76) | 90 (76) | <.001 |
| Race and ethnicity, no. (%) | 1794 | .07 | ||||
| Asian or Pacific Islander | 129 (7.2) | 99 (7.3) | 23 (7.1) | 7 (5.9) | .8 | |
| Hispanic | 657 (37) | 508 (38) | 101 (31) | 48 (41) | .052 | |
| Non-Hispanic Black | 315 (18) | 223 (17) | 77 (24) | 15 (13) | .004 | |
| Non-Hispanic White | 490 (27) | 372 (28) | 87 (27) | 31 (26) | >.9 | |
| Other | 203 (11) | 148 (11) | 38 (12) | 17 (14) | .5 | |
| Median (IQR) calendar week of admission | 1794 | 12 (11-14) | 12 (11-14) | 12 (12-14) | 12 (11-13) | .05 |
| Hour of admission, no. (%) | 1794 | |||||
| 12 am-4 am | 160 (8.9) | 114 (8.4) | 35 (11) | 11 (9.3) | .4 | |
| 5 am-9 am | 203 (11) | 152 (11) | 40 (12) | 11 (9.3) | .7 | |
| 10 am-2 pm | 564 (31) | 395 (29) | 121 (37) | 48 (41) | .002 | |
| 3 pm-7 pm | 558 (31) | 448 (33) | 75 (23) | 35 (30) | .002 | |
| 8 pm-11 pm | 309 (17) | 241 (18) | 55 (17) | 13 (11) | .2 | |
| Median (IQR) body mass indexa | 1697 | 30 (26-35) | 30 (26-34) | 29 (26-35) | 30 (26-35) | .5 |
| Preexisting conditions, no. (%) | 1794 | |||||
| Diabetes | 577 (32) | 400 (30) | 132 (40) | 45 (38) | <.001 | |
| Hypertension | 819 (46) | 555 (41) | 198 (61) | 66 (56) | <.001 | |
| Cardiac disease | 332 (19) | 214 (16) | 92 (28) | 26 (22) | <.001 | |
| Peripheral vascular disorder | 125 (7.0) | 76 (5.6) | 40 (12) | 9 (7.6) | <.001 | |
| Pulmonary disease | 389 (22) | 283 (21) | 80 (25) | 26 (22) | .4 | |
| Cancer | 109 (6.1) | 80 (5.9) | 26 (8.0) | 3 (2.5) | .1 | |
| Renal failure | 219 (12) | 91 (6.7) | 106 (33) | 22 (19) | <.001 | |
| Liver disease | 145 (8.1) | 99 (7.3) | 36 (11) | 10 (8.5) | .087 | |
| Coagulation | 158 (8.8) | 98 (7.3) | 45 (14) | 15 (13) | <.001 | |
| Elixhauser AHQR Index score, no. (%) | 1794 | |||||
| <0 | 552 (31) | 445 (33) | 77 (24) | 30 (25) | .002 | |
| 0 | 406 (23) | 343 (25) | 47 (14) | 16 (14) | <.001 | |
| 1-4 | 155 (8.6) | 125 (9.3) | 23 (7.1) | 7 (5.9) | .2 | |
| ≥5 | 681 (38) | 437 (32) | 179 (55) | 65 (55) | <.001 | |
| No. (%) of prior outpatient visits | 1794 | |||||
| 0 | 1130 (63) | 857 (63) | 192 (59) | 81 (69) | .13 | |
| 1-3 | 262 (15) | 206 (15) | 45 (14) | 11 (9.3) | .2 | |
| >3 | 402 (22) | 287 (21) | 89 (27) | 26 (22) | .06 | |
| No. (%) of prior inpatient visits | 1794 | 232 (13) | 162 (12) | 55 (17) | 15 (13) | .06 |
| Median (IQR) distance from hospital, milesb | 1794 | 3.7 (2.0-6.3) | 3.7 (2.0-6.3) | 3.9 (2.3-6.4) | 3.6 (1.8-5.8) | .4 |
| Patient characteristic . | Total no. of patients . | mSOFA score . | P value . | |||
|---|---|---|---|---|---|---|
| Overall . | 0-3 . | 4-7 . | >7 . | |||
| (n = 1794) . | (n = 1350; 75.3%) . | (n = 326; 18.2%) . | (n = 118; 6.6%) . | |||
| No. (%) of deaths | 1794 | 194 (11) | 68 (5.0) | 71 (22) | 55 (47) | <.001 |
| Median (IQR) length of stay, d | 1794 | 6 (3-11) | 5 (3-9) | 9 (5-17) | 12 (6-26) | <.001 |
| Median (IQR) nondeath length of stay, d | 1600 | 5 (3-10) | 5 (3-8) | 9 (5-16) | 18 (8-41) | <.001 |
| Type of health-care coverage, no. (%) | 1794 | |||||
| Private | 881 (49) | 674 (50) | 153 (47) | 54 (46) | .5 | |
| Medicare | 188 (10) | 115 (8.5) | 64 (20) | 9 (7.6) | <.001 | |
| Medicaid | 413 (23) | 323 (24) | 67 (21) | 23 (19) | .3 | |
| Uninsured | 312 (17) | 238 (18) | 42 (13) | 32 (27) | .002 | |
| Median (IQR) age, y | 1794 | 52 (42-59) | 51 (41-58) | 56 (47-60) | 54 (46-59) | <.001 |
| Male sex, no. (%) | 1794 | 1173 (65) | 835 (62) | 248 (76) | 90 (76) | <.001 |
| Race and ethnicity, no. (%) | 1794 | .07 | ||||
| Asian or Pacific Islander | 129 (7.2) | 99 (7.3) | 23 (7.1) | 7 (5.9) | .8 | |
| Hispanic | 657 (37) | 508 (38) | 101 (31) | 48 (41) | .052 | |
| Non-Hispanic Black | 315 (18) | 223 (17) | 77 (24) | 15 (13) | .004 | |
| Non-Hispanic White | 490 (27) | 372 (28) | 87 (27) | 31 (26) | >.9 | |
| Other | 203 (11) | 148 (11) | 38 (12) | 17 (14) | .5 | |
| Median (IQR) calendar week of admission | 1794 | 12 (11-14) | 12 (11-14) | 12 (12-14) | 12 (11-13) | .05 |
| Hour of admission, no. (%) | 1794 | |||||
| 12 am-4 am | 160 (8.9) | 114 (8.4) | 35 (11) | 11 (9.3) | .4 | |
| 5 am-9 am | 203 (11) | 152 (11) | 40 (12) | 11 (9.3) | .7 | |
| 10 am-2 pm | 564 (31) | 395 (29) | 121 (37) | 48 (41) | .002 | |
| 3 pm-7 pm | 558 (31) | 448 (33) | 75 (23) | 35 (30) | .002 | |
| 8 pm-11 pm | 309 (17) | 241 (18) | 55 (17) | 13 (11) | .2 | |
| Median (IQR) body mass indexa | 1697 | 30 (26-35) | 30 (26-34) | 29 (26-35) | 30 (26-35) | .5 |
| Preexisting conditions, no. (%) | 1794 | |||||
| Diabetes | 577 (32) | 400 (30) | 132 (40) | 45 (38) | <.001 | |
| Hypertension | 819 (46) | 555 (41) | 198 (61) | 66 (56) | <.001 | |
| Cardiac disease | 332 (19) | 214 (16) | 92 (28) | 26 (22) | <.001 | |
| Peripheral vascular disorder | 125 (7.0) | 76 (5.6) | 40 (12) | 9 (7.6) | <.001 | |
| Pulmonary disease | 389 (22) | 283 (21) | 80 (25) | 26 (22) | .4 | |
| Cancer | 109 (6.1) | 80 (5.9) | 26 (8.0) | 3 (2.5) | .1 | |
| Renal failure | 219 (12) | 91 (6.7) | 106 (33) | 22 (19) | <.001 | |
| Liver disease | 145 (8.1) | 99 (7.3) | 36 (11) | 10 (8.5) | .087 | |
| Coagulation | 158 (8.8) | 98 (7.3) | 45 (14) | 15 (13) | <.001 | |
| Elixhauser AHQR Index score, no. (%) | 1794 | |||||
| <0 | 552 (31) | 445 (33) | 77 (24) | 30 (25) | .002 | |
| 0 | 406 (23) | 343 (25) | 47 (14) | 16 (14) | <.001 | |
| 1-4 | 155 (8.6) | 125 (9.3) | 23 (7.1) | 7 (5.9) | .2 | |
| ≥5 | 681 (38) | 437 (32) | 179 (55) | 65 (55) | <.001 | |
| No. (%) of prior outpatient visits | 1794 | |||||
| 0 | 1130 (63) | 857 (63) | 192 (59) | 81 (69) | .13 | |
| 1-3 | 262 (15) | 206 (15) | 45 (14) | 11 (9.3) | .2 | |
| >3 | 402 (22) | 287 (21) | 89 (27) | 26 (22) | .06 | |
| No. (%) of prior inpatient visits | 1794 | 232 (13) | 162 (12) | 55 (17) | 15 (13) | .06 |
| Median (IQR) distance from hospital, milesb | 1794 | 3.7 (2.0-6.3) | 3.7 (2.0-6.3) | 3.9 (2.3-6.4) | 3.6 (1.8-5.8) | .4 |
Abbreviations: AHQR, Agency for Healthcare Research and Quality; IQR, interquartile range; mSOFA, modified sequential organ failure assessment.
a Weight (kg)/height (m)2.
b 1 mile = 1.6 km.
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